Activation of an S6/H4 Kinase (PAK 65) from Human Placenta by Intramolecular and Intermolecular Autophosphorylation (open access)

Activation of an S6/H4 Kinase (PAK 65) from Human Placenta by Intramolecular and Intermolecular Autophosphorylation

Article proposing a model in which phosphorylation of sites 1 and 2 occurs sequentially. The model proposes that trypsin treatment of the inactive holoenzyme removes an inhibitory rac-binding domain which blocks MgATP access to the catalytic site. The pseudosubstrate domain at site 1 is autophosphorylated and subsequent bimolecular autophosphorylation at site 2 fully opens the catalytic site.
Date: September 8, 1995
Creator: Benner, Gretchen E.; Dennis, Patrick B. & Masaracchia, Ruthann A.
System: The UNT Digital Library
Activation of an S6 Kinase From Human Placenta by Autophosphorylation (open access)

Activation of an S6 Kinase From Human Placenta by Autophosphorylation

Article describing a novel S6 kinase isolated from human placenta which autoactivates through autophosphorylation in vitro. The data supports the hypothesis that this previously uncharacterized S6 kinase belongs to a unique family of protein kinases which utilize autophosphorylation as part of their in vivo activation mechanism.
Date: September 15, 1993
Creator: Dennis, Patrick B. & Masaracchia, Ruthann A.
System: The UNT Digital Library
Altered embryonic development in northern bobwhite quail (Colinus virginianus) induced by pre-incubation oscillatory thermal stresses mimicking global warming predictions (open access)

Altered embryonic development in northern bobwhite quail (Colinus virginianus) induced by pre-incubation oscillatory thermal stresses mimicking global warming predictions

This article describes the exposure of freshly laid bobwhite quail eggs to one of five thermal regimes during a 12 day pre-incubation period.
Date: March 31, 2017
Creator: Reyna, Kelly S. & Burggren, Warren W.
System: The UNT Digital Library
Brain Inflammation, Blood Brain Barrier dysfunction and Neuronal Synaptophysin Decrease after Inhalation Exposure to Titanium Dioxide Nano-aerosol in Aging Rats (open access)

Brain Inflammation, Blood Brain Barrier dysfunction and Neuronal Synaptophysin Decrease after Inhalation Exposure to Titanium Dioxide Nano-aerosol in Aging Rats

This article focuses on the consequences of TiO₂ distribution on the central nervous system and particularly on the blood-brain barrier functions.
Date: June 15, 2017
Creator: Disdier, Clémence; Chalansonnet, Monique; Gagnaire, François; Gaté, Laurent; Cosnier, Frédéric; Devoy, Jérôme et al.
System: The UNT Digital Library
A Combined Metabolomics and Fluxomics Analysis Identifies Steps Limiting Oil Synthesis in Maize Embryos (open access)

A Combined Metabolomics and Fluxomics Analysis Identifies Steps Limiting Oil Synthesis in Maize Embryos

Article comparing the metabolism of embryos from two different maize lines, Alex and LH59, to test the hypothesis that directly changing their carbon metabolism may be the key to increasing oil content in maize kernels without affecting yield.
Date: September 17, 2019
Creator: Alonso, Ana Paula; Cocuron, Jean-Christophe; Koubaa, Mohamed; Kimmelfield, Rebecca & Ross, Zacchary
System: The UNT Digital Library
Complete Genome Sequences of the Novel Cluster BP Phages Infecting Streptomyces sanglieri, AxeJC, Cumberbatch, Eastland, Eklok, HFrancette, Ignacio, Piccadilly, and Vondra (open access)

Complete Genome Sequences of the Novel Cluster BP Phages Infecting Streptomyces sanglieri, AxeJC, Cumberbatch, Eastland, Eklok, HFrancette, Ignacio, Piccadilly, and Vondra

Article describes the Streptomyces sanglieri bacteriophages AxeJC, Cumberbatch, Eastland,Eklok, HFrancette, Ignacio, Piccadilly, and Vondra form a novel actinobacteriophage cluster,BP. These siphoviruses have circularly permuted genomes with an average size of 37,700 bp and a GC content of 71%. Each genome contains approximately 58 protein-coding genes, with no tRNAs.
Date: September 14, 2022
Creator: Nath, Sreemoye; Sulaiman, Ahmad; Maneekul, Jindanuch; Bhuiyan, Swapan; Layton, Sonya R.; Menchaca, Carolina et al.
System: The UNT Digital Library
Computational design of environmental sensors for the potent opioid fentanyl (open access)

Computational design of environmental sensors for the potent opioid fentanyl

This article describes the computational design of proteins that bind the potent analgesic fentanyl.
Date: September 19, 2017
Creator: Bick, Matthew J.; Greisen, Per J.; Morey, Kevin J.; Antunes, Mauricio S.; La, David; Sankaran, Banumathi et al.
System: The UNT Digital Library
Convective oxygen transport during development in embryos of the snapping turtle Chelydra serpentina (open access)

Convective oxygen transport during development in embryos of the snapping turtle Chelydra serpentina

This article describes a study investigating the maturation of convective oxygen transport in embryos of the snapping turtle (Chelydra serpentina). Measurements included: mass, oxygen consumption, heart rate, blood oxygen content and affinity and blood flow distribution at 50%, 70% and 90% of the incubation period.
Date: September 24, 2018
Creator: Sartori, Marina R.; Kohl, Zachary F.; Taylor, Edwin W.; Abe, Augusto S. & Crossley, Dane A., II
System: The UNT Digital Library
Critical Developmental Windows for Morphology and Hematology Revealed by Intermittent and Continuous Hypoxic Incubation in Embryos of Quail (Coturnix Coturnix) (open access)

Critical Developmental Windows for Morphology and Hematology Revealed by Intermittent and Continuous Hypoxic Incubation in Embryos of Quail (Coturnix Coturnix)

This article describes the exposure of quail embryos in the intact egg to hypoxia during "early" or "late" incubation for their entire 16-18 day incubation to determine critical windows for viability and growth.
Date: November 14, 2016
Creator: Burggren, Warren W. & Elmonoufy, Nourhan
System: The UNT Digital Library
Developmental programming of DNA methylation and gene expression patterns is associated with extreme cardiovascular tolerance to anoxia in the common snapping turtle (open access)

Developmental programming of DNA methylation and gene expression patterns is associated with extreme cardiovascular tolerance to anoxia in the common snapping turtle

This article explores DNA methylation's role in the regulation of gene expression in reptiles. Results show that embryonic hypoxia programs DNA methylation and gene expression patterns and that these changes are associated with enhanced cardiac anoxia tolerance in snapping turtles later in life.
Date: September 6, 2021
Creator: Ruhr, Ilan; Bierstedt, Jacob; Rhen, Turk; Das, Debojyoti; Singh, Sunil Kumar; Miller, Solielle et al.
System: The UNT Digital Library
Dry blood spot samples to monitor immune-associated mRNA expression in intervention studies: Impact of Baker's yeast beta glucan (open access)

Dry blood spot samples to monitor immune-associated mRNA expression in intervention studies: Impact of Baker's yeast beta glucan

Article describes how monitoring immunological response to physical stressors in a field setting is challenging because existing methods require a laboratory visit and traditional blood collection via venipuncture. The purpose of this study was to determine if our optimized dry blood spot (DBS) methodology yields sufficient total RNA to quantify the effect of Baker's Yeast Beta Glucan supplementation on post-exercise mRNA expression.
Date: September 22, 2023
Creator: McFarlin, Brian K.; Bridgeman, Elizabeth A.; Vingren, Jakob L. & Will, David W.
System: The UNT Digital Library
A dynamic model of lignin biosynthesis in Brachypodium distachyon (open access)

A dynamic model of lignin biosynthesis in Brachypodium distachyon

Article proposes a dynamic mathematical model that integrates various datasets and other information regarding the lignin pathway in Brachypodium distachyon and permits explanations for some counterintuitive observations.
Date: September 19, 2018
Creator: Faraji, Mojdeh; Fonseca, Luis L.; Escamilla-Treviño, Luis; Barros-Rios, Jaime; Engle, Nancy L.; Yang, Zamin K. et al.
System: The UNT Digital Library
A dynamic model of lignin biosynthesis in Brachypodium distachyon (open access)

A dynamic model of lignin biosynthesis in Brachypodium distachyon

This article proposes a dynamic mathematical model that integrates various datasets and other information regarding the lignin pathway in Brachypodium distachyon and permits explanations for some counterintuitive observations.
Date: September 19, 2018
Creator: Faraji, Mojdeh; Fonseca, Luis L.; Escamilla-Treviño, Luis; Barros, Jaime; Engle, Nancy L.; Yang, Zamin K. et al.
System: The UNT Digital Library
Editorial: Advances in Plant-Hemipteran Interactions (open access)

Editorial: Advances in Plant-Hemipteran Interactions

This editorial discusses sixteen manuscripts which address the physiology and molecular biology of plant-hemipteran interactions at different levels.
Date: September 21, 2017
Creator: Shah, Jyoti & Walling, Linda
System: The UNT Digital Library
Evaluation of pathways to the C-glycosyl isoflavone puerarin in roots of kudzu (Pueraria montana lobata) (open access)

Evaluation of pathways to the C-glycosyl isoflavone puerarin in roots of kudzu (Pueraria montana lobata)

Article describes how kudzu produces both O- and C-glycosylated isoflavones, with puerarin (C-glucosyl daidzein) as an important bioactive compound. The authors go on to explain how expression of recombinant UGTs in Escherichia coli and candidate C-glycosyltransferases in Medicago truncatula were used to explore substrate specificities, and gene silencing of UGT and key isoflavone biosynthetic genes in kudzu hairy roots employed to test hypotheses concerning the substrate(s) for C-glycosylation.
Date: September 2, 2022
Creator: Adolfo, Laci M.; Burks, David J.; Rao, Xiaolan; Alvarez-Hernandez, Anislay & Dixon, R. A.
System: The UNT Digital Library
A gene-editing/complementation strategy for tissue-specific lignin reduction while preserving biomass yield (open access)

A gene-editing/complementation strategy for tissue-specific lignin reduction while preserving biomass yield

This article develops a method, using a single DNA construct that uses CRISPR–Cas9 gene editing to knock-out expression of an endogenous gene of lignin monomer biosynthesis while at the same time expressing a modified version of the gene’s open reading frame that escapes cutting by the Cas9 system and complements the introduced mutation in a tissue-specific manner. This method is applicable to any plant species in which transformation and gene editing are feasible and validated vessel-specific promoters are available.
Date: September 3, 2021
Creator: Yu, Hasi; Liu, Chang & Dixon, R. A.
System: The UNT Digital Library
Habitat amount or landscape configuration: Emerging HotSpot analysis reveals the importance of habitat amount for a grassland bird in South Dakota (open access)

Habitat amount or landscape configuration: Emerging HotSpot analysis reveals the importance of habitat amount for a grassland bird in South Dakota

The authors of the article used pheasants (Phasianus colchicus) across South Dakota, USA as a model species to identify environmental factors driving spatiotemporal variation in population productivity. They found that the amount of grassland at a local spatial scale was the primary factor influencing an area being a HotSpot.
Date: September 26, 2022
Creator: Harsh, Sprih; Lonsinger, Robert C. & Gregory, Andrew
System: The UNT Digital Library
An “ideal lignin” facilitates full biomass utilization (open access)

An “ideal lignin” facilitates full biomass utilization

This article describes the ideal nature of the Catechyl lignin (C-lignin) via a revised compositional characterization of the vanilla seed coat fiber, new features of the C-lignin's reactivity and stability, and successful attempts at converting it to monomers in near-quantitative yields.
Date: September 28, 2018
Creator: Li, Yanding; Shuai, Li; Kim, Hoon; Hussain Motagamwala, Ali; Mobley, Justin K.; Yue, Fengxia et al.
System: The UNT Digital Library
Identification of bottlenecks in the accumulation of cyclic fatty acids in camelina seed oil (open access)

Identification of bottlenecks in the accumulation of cyclic fatty acids in camelina seed oil

This article proposes a model for the accumulation of substantial levels of cyclopropane fatty acids (CPA) in camelina, and discusses the differences between CPA accumulation in camelina and Arabidopsis.
Date: July 10, 2017
Creator: Yu, Xiao-Hong; Cahoon, Rebecca E.; Horn, Patrick J.; Shi, Hai; Prakash, Richa R.; Cai, Yuanheng et al.
System: The UNT Digital Library
Improved Campephiline detection: An experiment conducted with the Magellanic Woodpecker (open access)

Improved Campephiline detection: An experiment conducted with the Magellanic Woodpecker

Article describes a study which tried to determine which of three methods (useing a drumming device to simulate a double‐knock (i.e., territorial acoustical signal), broadcasting a territorial call, or passively listening) best results in a detection of Magellanic Woodpeckers (Campephilus magellanicus ), and if weather variables influence detection probability.
Date: September 27, 2019
Creator: Wynia, Amy L.; Rolland, Virginie & Jiménez, Jaime E.
System: The UNT Digital Library
Metallic nanoparticle production and exposure/deposition system for toxicological research applications using zebrafish (open access)

Metallic nanoparticle production and exposure/deposition system for toxicological research applications using zebrafish

Article presents a method that provides a novel way to synthesize NPs and expose biological organisms for various toxicological analysis.
Date: September 3, 2020
Creator: Nayek, Subhayu; Aguilar, Roberto; Juel, Lauren A. & Verbeck, Guido F.
System: The UNT Digital Library
Multi-omic characterization of bifunctional peroxidase 4-coumarate 3-hydroxylase knockdown in Brachypodium distachyon provides insights into lignin modification associated pleiotropic effects (open access)

Multi-omic characterization of bifunctional peroxidase 4-coumarate 3-hydroxylase knockdown in Brachypodium distachyon provides insights into lignin modification associated pleiotropic effects

Article discusses how a bifunctional peroxidase enzyme, 4-coumarate 3-hydroxylase (C3H/APX), provides a parallel route to the shikimate shunt pathway for the conversion of 4-coumarate to caffeate in the early steps of lignin biosynthesis. Here, a multi-omic approach was used to characterize molecular changes resulting from C3H/APX-KD associated lignin modification and negative growth phenotype in Brachypodium distachyon.
Date: September 28, 2022
Creator: Shrestha, Him K.; Fichman, Yosef; Engle, Nancy L.; Tschaplinski, Timothy J.; Mittler, Ron; Dixon, R. A. et al.
System: The UNT Digital Library
The osmorespiratory compromise in the euryhaline killifish: water regulation during hypoxia (open access)

The osmorespiratory compromise in the euryhaline killifish: water regulation during hypoxia

Article studying water regulation during hypoxia in euryhaline killifish.
Date: September 24, 2019
Creator: Mager, Edward M.; Wood, Chris M.; Ruhr, Ilan M.; Schauer, Kevin L.; Wang, Yadong; McDonald, M. Danielle et al.
System: The UNT Digital Library
Parental stressor exposure simultaneously conveys both adaptive and maladaptive larval phenotypes through epigenetic inheritance in the zebrafish (Danio rerio) (open access)

Parental stressor exposure simultaneously conveys both adaptive and maladaptive larval phenotypes through epigenetic inheritance in the zebrafish (Danio rerio)

This article is a study using crude oil as an example of an environmental stressor in adult zebrafish. The offspring obtained were then assessed for transgenerational epigenetic transfer of oil-induced phenotypes. The authors conclude that epigenetic transgenerational inheritance can lead to an immediate and simultaneous inheritance of both beneficial and maladaptive traits in a large proportion of the F1 larvae. The adaptive responses may help fish populations survive when facing transient environmental stressors.
Date: September 5, 2019
Creator: Bautista, Naim M. & Burggren, Warren W.
System: The UNT Digital Library