States

Transcriptome Analysis Uncovers the Gene Expression Profile of Hemileia vastatrix (Race XXXIII) during the Interactions with Resistant and Susceptible Coffee (open access)

Transcriptome Analysis Uncovers the Gene Expression Profile of Hemileia vastatrix (Race XXXIII) during the Interactions with Resistant and Susceptible Coffee

This article presents research to sequence the transcriptome of H. vastatrix race XXXIII to obtain a database for use as a reference in studies of the interaction between the fungus and coffee. In addition, the authors aim to identify differentially expressed genes that have the potential to act as effector proteins during the interaction.
Date: December 27, 2021
Creator: Castro, Isabel Samila Lima; Freitas-Lopes, Rejane do Livramento; de Siqueira Ferreira, Sávio; Maciel, Talles Eduardo Ferreira; Florez, Juan Carlos; Zambolim, Eunize Maciel et al.
Object Type: Article
System: The UNT Digital Library
Inhaled diesel exhaust particles result in microbiome‑related systemic inflammation and altered cardiovascular disease biomarkers in C57Bl/6 male mice (open access)

Inhaled diesel exhaust particles result in microbiome‑related systemic inflammation and altered cardiovascular disease biomarkers in C57Bl/6 male mice

Article discusses the authors' investigation the hypothesis that exposure to inhaled diesel exhaust particles alters the gut microbiome and promotes microbial-related inflammation and cardiovascular disease biomarkers. To determine whether probiotics could prevent diet or DEP exposure mediated alterations in the gut microbiome or systemic outcomes, a subset of animals on the HF diet were treated orally with 0.3 g/day (~ 7.5 × 108 CFU/day) of Winclove Ecologic® Barrier probiotics throughout the study.
Date: February 9, 2022
Creator: Phillippi, Danielle T.; Daniel, Sarah; Pusadkar, Vaidehi; Youngblood, Victoria L.; Nguyen, Kayla N.; Azad, Rajeev K. et al.
Object Type: Article
System: The UNT Digital Library
Cascading effects of COVID-19 on population mobility and air quality: An exploration including place characteristics using geovisualization (open access)

Cascading effects of COVID-19 on population mobility and air quality: An exploration including place characteristics using geovisualization

Article examining the population mobility and air quality before and after the lockdown (mandated restriction of activity) during the public health response to COVID-19. This article is part of the Special Issue on COVID-19.
Date: January 22, 2022
Creator: Atkinson, Samuel F.; Kala, Abhishek K. & Tiwari, Chetan
Object Type: Article
System: The UNT Digital Library
Larval Development in Tropical Gar (Atractosteus tropicus) Is Dependent on the Embryonic Thermal Regime: Ecological Implications under a Climate Change Context (open access)

Larval Development in Tropical Gar (Atractosteus tropicus) Is Dependent on the Embryonic Thermal Regime: Ecological Implications under a Climate Change Context

Article presents research on how temperature affects fish populations. The study shows how changes in temperature may induce craniofacial and morphological alterations in fish during early stages and contribute to understanding the possible effects of global warming in early development of fish and its ecological implications.
Date: December 14, 2021
Creator: Cordova-de la Cruz, Simrith E.; Riesco, Marta F.; Martínez-Bautista, Gil; Calzada-Ruiz, Daniel; Martínez-Burguete, Talhia; Peña-Marín, Emyr S. et al.
Object Type: Article
System: The UNT Digital Library
The metabolic cost of turning right side up in the Mediterranean spur-thighed tortoise (Testudo graeca) (open access)

The metabolic cost of turning right side up in the Mediterranean spur-thighed tortoise (Testudo graeca)

Article examining the the metabolic cost of self-righting in the terrestrial Mediterranean spur-thighed tortoise using respirometry and kinematic video analysis and comparing this to the metabolic cost of locomotion at a moderate, easily sustainable speed. The results found that self-righting is, relatively, metabolically expensive and costs around two times the mass-specific power required to walk.
Date: January 10, 2022
Creator: Ewart, Heather E.; Tickle, Peter G.; Sellers, William I.; Lambertz, Markus; Crossley, Dane A., II & Codd, Jonathan R.
Object Type: Article
System: The UNT Digital Library
Identification of Pueraria spp. through DNA barcoding and comparative transcriptomics (open access)

Identification of Pueraria spp. through DNA barcoding and comparative transcriptomics

This article presents research where various kudzu accessions were analyzed through barcoding and comparative transcriptomics, generating tools for identification and molecular pathway analysis.
Date: January 3, 2022
Creator: Adolfo, Laci M.; Rao, Xiaolan & Dixon, R. A.
Object Type: Article
System: The UNT Digital Library
Instructional Models for Course-Based Research Experience (CRE) Teaching (open access)

Instructional Models for Course-Based Research Experience (CRE) Teaching

This article presents a study that was done over a period of 3 years to explicate the instructional processes involved in teaching an undergraduate course-based research experience (CRE). The study presented here delineated a set of specific instructional practices used by active CRE instructors and modeled the relations between the use of these practices and specified outcomes. The resultant educational models should provide clarification of the ways in which the aims of CRE can be effectively achieved by instructors.
Date: January 3, 2022
Creator: Hanauer, David I.; Graham, Mark J.; Arnold, Rachel J.; Ayuk, Mary A.; Balish, Mitchell F.; Beyer, Andrea R. et al.
Object Type: Article
System: The UNT Digital Library
Role of ribosomal RNA released from red cells in blood coagulation in zebrafish and humans (open access)

Role of ribosomal RNA released from red cells in blood coagulation in zebrafish and humans

This article identifies that an rRNA released in hemolysis activates clotting in human and zebrafish plasma. Furthermore, it shows that fish Hgfac plays a role in rRNA-mediated activation of coagulation.
Date: November 17, 2021
Creator: Alharbi, Abdulmajeed; Iyer, Neha; Al Qaryoute, Ayah; Raman, Revathi; Burks, David J.; Azad, Rajeev K. et al.
Object Type: Article
System: The UNT Digital Library
Crowdsourcing biocuration: the Community Assessment of Community 1 Annotation with Ontologies (CACAO) (open access)

Crowdsourcing biocuration: the Community Assessment of Community 1 Annotation with Ontologies (CACAO)

Article describing an approach to expand biocuration through crowdsourcing with undergraduates in the community-oriented wiki framework for GO annotation called the Gene Ontology Normal Usage Tracking System (GONUTS). This multiplies the number of high-quality annotations in international databases, enriches the coverage of the literature on normal gene function, and pushes the field in new directions.
Date: October 28, 2021
Creator: Ramsey, Jolene; McIntosh, Brenley; Renfro, Daniel; Aleksander, Susan A.; LaBonte, Sandra; Ross, Curtis et al.
Object Type: Article
System: The UNT Digital Library
Beyond the Chicken: Alternative Avian Models for Developmental Physiological Research (open access)

Beyond the Chicken: Alternative Avian Models for Developmental Physiological Research

This article is a review examining the characteristics that make an animal model attractive for developmental research and explores opportunities presented by the embryo to adult continuum of alternative bird models including quail, ratites, songbirds, birds of prey, and corvids.
Date: October 21, 2021
Creator: Flores-Santin, Josele & Burggren, Warren W.
Object Type: Article
System: The UNT Digital Library
Trypsin induces an aversive response in zebrafish by PAR2 activation in keratinocytes (open access)

Trypsin induces an aversive response in zebrafish by PAR2 activation in keratinocytes

Article using zebrafish as a model and identifies that trypsin induces an aversive response in zebrafish larvae and adult zebrafish. Results show that the trypsin activates PAR2 on keratinocytes signaling the brain, and this pathway of trypsin-induced escape response will provide a unique communication mechanism in zebrafish.
Date: October 8, 2021
Creator: Alsrhani, Abdullah; Raman, Revathi & Jagadeeswaran, Pudur
Object Type: Article
System: The UNT Digital Library
Developmental programming of DNA methylation and gene expression patterns is associated with extreme cardiovascular tolerance to anoxia in the common snapping turtle (open access)

Developmental programming of DNA methylation and gene expression patterns is associated with extreme cardiovascular tolerance to anoxia in the common snapping turtle

This article explores DNA methylation's role in the regulation of gene expression in reptiles. Results show that embryonic hypoxia programs DNA methylation and gene expression patterns and that these changes are associated with enhanced cardiac anoxia tolerance in snapping turtles later in life.
Date: September 6, 2021
Creator: Ruhr, Ilan; Bierstedt, Jacob; Rhen, Turk; Das, Debojyoti; Singh, Sunil Kumar; Miller, Solielle et al.
Object Type: Article
System: The UNT Digital Library
A gene-editing/complementation strategy for tissue-specific lignin reduction while preserving biomass yield (open access)

A gene-editing/complementation strategy for tissue-specific lignin reduction while preserving biomass yield

This article develops a method, using a single DNA construct that uses CRISPR–Cas9 gene editing to knock-out expression of an endogenous gene of lignin monomer biosynthesis while at the same time expressing a modified version of the gene’s open reading frame that escapes cutting by the Cas9 system and complements the introduced mutation in a tissue-specific manner. This method is applicable to any plant species in which transformation and gene editing are feasible and validated vessel-specific promoters are available.
Date: September 3, 2021
Creator: Yu, Hasi; Liu, Chang & Dixon, R. A.
Object Type: Article
System: The UNT Digital Library
Patch characteristics and domestic dogs differentially affect carnivore space use in fragmented landscapes in southern Chile (open access)

Patch characteristics and domestic dogs differentially affect carnivore space use in fragmented landscapes in southern Chile

This article's aim is to determine whether (a) the spatial use of domestic dogs increases with habitat destruction, and (b) domestic dogs and habitat destruction drive the spatial use of native carnivores in a heavily degraded agricultural landscape. Conclusions highlight that domestic dog occupancy was positively correlated with habitat loss and future conditions of increased fragmentation and habitat loss will likely increase the potential contact between domestic dogs and native carnivores.
Date: August 30, 2021
Creator: Malhotra, Rumaan; Jiménez, Jaime E. & Harris, Nyeema C;
Object Type: Article
System: The UNT Digital Library
Phylogenetic Occurrence of the Phenylpropanoid Pathway and Lignin Biosynthesis in Plants (open access)

Phylogenetic Occurrence of the Phenylpropanoid Pathway and Lignin Biosynthesis in Plants

This article is a review summarizing recent progress in defining the lignin biosynthetic pathway in lycophytes, monilophytes, gymnosperms, and angiosperms. This review provides new insights into the genetic engineering of the lignin biosynthetic pathway to overcome biomass recalcitrance in bioenergy crops.
Date: August 17, 2021
Creator: Yao, Tao; Feng, Kai; Xie, Meng; Barros, Jaime; Tschaplinski, Timothy J.; Tuskan, Gerald et al.
Object Type: Article
System: The UNT Digital Library
Magnesium and Fibromyalgia: A Literature Review (open access)

Magnesium and Fibromyalgia: A Literature Review

This article investigates if the widespread use of magnesium in fibromyalgia is supported by evidence in the literature. This review provides a layout of the studies examining the correlation between body magnesium levels and fibromyalgia and elaborates on the trials testing the effectiveness of magnesium in treating different clinical parameters of fibromyalgia.
Date: August 14, 2021
Creator: Boulis, Michael; Boulis, Mary & Clauw, Daniel
Object Type: Article
System: The UNT Digital Library
High degree of non-genetic phenotypic variation in the vascular system of crayfish: a discussion of possible causes and implications (open access)

High degree of non-genetic phenotypic variation in the vascular system of crayfish: a discussion of possible causes and implications

This article studies the hemolymph vascular system (HVS) in two cambarid crayfishes, i.e. the Marbled Crayfish, Procambarus virginalis Lyko, 2017 and the Spiny Cheek Crayfish, Faxonius limosus (Rafinesque, 1817) in regard to areas of non-genetic phenotypic variation.
Date: August 12, 2021
Creator: Scholz, Stephan; Göpel, Torben; Richter, Stefan & Wirkner, Christian S.
Object Type: Article
System: The UNT Digital Library
Inhibition of Very Long Chain Fatty Acids Synthesis Mediates PI3P Homeostasis at Endosomal Compartments (open access)

Inhibition of Very Long Chain Fatty Acids Synthesis Mediates PI3P Homeostasis at Endosomal Compartments

This article uses metazachlor, an inhibitor of VLCFA synthesis, to find that VLCFAs are involved in the TGN/MVB distribution of PI3P. This effect is independent from either synthesis of PI3P by PI3-kinase or degradation of PI(3,5)P2 into PI3P by the SUPPRESSOR OF ACTIN1 (SAC1) phosphatase. Results suggest that PI3P might be transferable from TGN to MVBs and that VLCFAs act in this process.
Date: August 6, 2021
Creator: Ito, Yoko; Esnay, Nicolas; Fougère, Louise; Platre, Matthieu Pierre; Cordelières, Fabrice; Jaillais, Yvon et al.
Object Type: Article
System: The UNT Digital Library
Knockdown screening of chromatin binding and regulatory proteins in zebrafish identified Suz12b as a regulator of tfpia and an antithrombotic drug target (open access)

Knockdown screening of chromatin binding and regulatory proteins in zebrafish identified Suz12b as a regulator of tfpia and an antithrombotic drug target

Article identifying novel epigenetic regulators for tfpia and exploiting this information to discover a drug that enhances tfpia mRNA levels and prolongation of TTO. This discovery provides the basis for testing whether UNC6852 could be used as an antithrombotic drug.
Date: July 27, 2021
Creator: Raman, Revathi; Fallatah, Weam; Al Qaryoute, Ayah; Dhinoja, Sanchi & Jagadeeswaran, Pudur
Object Type: Article
System: The UNT Digital Library
Scaling of axial muscle architecture in juvenile Alligator mississippiensis reveals an enhanced performance capacity of accessory breathing mechanisms (open access)

Scaling of axial muscle architecture in juvenile Alligator mississippiensis reveals an enhanced performance capacity of accessory breathing mechanisms

Article describing the anatomy of the trunk muscles, their properties that determine muscle performance (mass, length and physiological cross-sectional area [PCSA]) and investigating their scaling in juvenile Alligator mississippiensis spanning an order of magnitude in body mass (359 g–5.5 kg). Findings support existing anecdotal evidence that crocodilians shift their breathing mechanics as they increase in size.
Date: July 23, 2021
Creator: Rose, Kayleigh A. R.; Tickle, Peter G.; Elsey, Ruth M.; Sellers, William I.; Crossley, Dane A., II & Codd, Jonathan R.
Object Type: Article
System: The UNT Digital Library
Developmental thyroid disruption causes long-term impacts on immune cell function and transcriptional responses to pathogen in a small fish model (open access)

Developmental thyroid disruption causes long-term impacts on immune cell function and transcriptional responses to pathogen in a small fish model

This article explores the connection between thyroid hormones (THs) and immune systems in fish. This article is noteworthy as disruption of the thyroid system during development, which can occur in response to chemicals present in the environment, may have lasting effects on immune function in adulthood for fish.
Date: July 14, 2021
Creator: Thornton Hampton, Leah M.; Finch, Miranda G.; Martyniuk, Christopher J.; Venables, Barney J. & Jeffries, Marlo K. Sellin
Object Type: Article
System: The UNT Digital Library
Sphingolipids mediate polar sorting of PIN2 through phosphoinositide consumption at the trans-Golgi network (open access)

Sphingolipids mediate polar sorting of PIN2 through phosphoinositide consumption at the trans-Golgi network

Article discovering a mechanism for how sphingolipids mediate phosphoinositide homeostasis at the TGN in plant cells. The data presented identifies a mode of action of sphingolipids in lipid interplay at the TGN during protein sorting.
Date: July 13, 2021
Creator: Ito, Yoko; Esnay, Nicolas; Platre, Matthieu Pierre; Wattelet-Boyer, Valérie; Noack, Lise C.; Fougère, Louise et al.
Object Type: Article
System: The UNT Digital Library
Structural Modeling and in planta Complementation Studies Link Mutated Residues of the Medicago truncatula Nitrate Transporter NPF1.7 to Functionality in Root Nodules (open access)

Structural Modeling and in planta Complementation Studies Link Mutated Residues of the Medicago truncatula Nitrate Transporter NPF1.7 to Functionality in Root Nodules

This article combines in silico structural predictions with in planta complementation of the severely defective mtnip-1 mutant plants to understand the role of a series of distinct amino acids in the transporter’s function. The findings add to the knowledge of the mechanism of alternative conformational changes as well as symport transport in NPFs and enhance knowledge of the mechanisms for nitrate signaling.
Date: July 1, 2021
Creator: Yu, Yao-Chuan; Dickstein, Rebecca & Longo, Antonella
Object Type: Article
System: The UNT Digital Library
The Long-Term Effects of Developmental Hypoxia on Cardiac Mitochondrial Function in Snapping Turtles (open access)

The Long-Term Effects of Developmental Hypoxia on Cardiac Mitochondrial Function in Snapping Turtles

This article investigates the long-term effects of developmental hypoxia on mitochondrial function in a species that regularly encounters hypoxia during development. Findings speculate that adjustments might improve mitochondrial hypoxia tolerance, which would be beneficial for turtles during breath-hold diving and overwintering in anoxic environments.
Date: June 28, 2021
Creator: Galli, Gina L. J.; Ruhr, Ilan M.; Crossley, Janna & Crossley, Dane A., II
Object Type: Article
System: The UNT Digital Library