Flexible and Stretchable Bioelectronics (open access)

Flexible and Stretchable Bioelectronics

Article reviewing several several flexible and stretchable materials used as substrate, stretchable electrical conduits and encapsulation, design modifications for stretchability, fabrication techniques, methods of signal transmission and monitoring, and the power sources for these stretchable bioelectronics. Ultimately, these bioelectronic devices can be used for wide range of applications from skin bioelectronics and biosensing devices, to neural implants for diagnostic or therapeutic purposes.
Date: December 20, 2021
Creator: Chitrakar, Chandani; Hedrick, Eric; Adegoke, Lauren & Ecker, Melanie
System: The UNT Digital Library
Wearable airbag technology and machine learned models to mitigate falls after stroke (open access)

Wearable airbag technology and machine learned models to mitigate falls after stroke

Article discusses wearable airbag technology that has been designed to detect and mitigate fall impact. However, this technology has not been validated for the stroke population, so authors investigated whether population-specific training data and modeling parameters are required to pre-detect falls in a chronic stroke population.
Date: June 17, 2022
Creator: Botonis, Olivia K.; Harari, Yaar; Embry, Kyle R.; Mummidisetty, Chaithanya K.; Riopelle, David; Giffhorn, Matt et al.
System: The UNT Digital Library
Pathological Targets for Treating Temporal Lobe Epilepsy: Discoveries From Microscale to Macroscale (open access)

Pathological Targets for Treating Temporal Lobe Epilepsy: Discoveries From Microscale to Macroscale

This review article summarizes the latest neuropathological discoveries at the molecular, cellular, and tissue levels involving both animal and patient studies, aiming to explore epileptogenesis and highlight new potential targets in the diagnosis and treatment of temporal lobe epilepsy (TLE).
Date: January 7, 2022
Creator: You, Jing; Huang, Haiyan; Chan, Clement T. Y. & Li, Lin
System: The UNT Digital Library
A consensus statement on detection of hippocampal sharp wave ripples and differentiation from other fast oscillations (open access)

A consensus statement on detection of hippocampal sharp wave ripples and differentiation from other fast oscillations

Article suggests that common standards for recording, detection, and reporting for intracranial recordings in humans that suggest their role in episodic and semantic memory does not exist. Authors of the article outline the methodological challenges involved in detecting ripple events and offer practical recommendations to improve separation from other high-frequency oscillations, and argue that shared experimental, detection, and reporting standards will provide a solid foundation for future translational discovery.
Date: October 12, 2022
Creator: Liu, Anli A.; Henin, Simon; Abbaspoor, Saman; Bragin, Anatol; Buffalo, Elizabeth A.; Farrell, Jordan S. et al.
System: The UNT Digital Library
An approach for reliably identifying high-frequency oscillations and reducing false-positive detections (open access)

An approach for reliably identifying high-frequency oscillations and reducing false-positive detections

Article states that high-frequency oscillation (HFO), classified as ripples (80-240 Hz) and fast ripples (240-500 Hz), is regarded as a promising biomarker of epilepsy. The authors presented an integrated, multi-layered procedure capable of automatically rejecting HFOs from a variety of common false positives, such as motion, background signals, and sharp transients.
Date: September 2, 2022
Creator: Zhou, Yufeng; You, Jing; Kumar, Udaya; Weiss, Shennan A.; Bragin, Anatol; Engel Jr., Jerome et al.
System: The UNT Digital Library
Current methods for fabricating 3D cardiac engineered constructs (open access)

Current methods for fabricating 3D cardiac engineered constructs

Article is a review highlighting the various cell types found in cardiac tissues and how they correspond with current advanced fabrication methods for creating cardiac engineered constructs.
Date: May 20, 2022
Creator: Rogozinski, Nicholas; Yanez, Apuleyo; Bhoi, Rahulkumar; Lee, Moo-Yeal & Yang, Huaxiao
System: The UNT Digital Library
Nanocrown electrodes for parallel and robust intracellular recording of cardiomyocytes (open access)

Nanocrown electrodes for parallel and robust intracellular recording of cardiomyocytes

Article develops vertically-aligned nanocrown electrodes that are mechanically robust and achieve > 99% success rates in obtaining intracellular access through electroporation. This technology development provides an advancement towards establishing an iAP screening assay for preclinical evaluation of drug-induced arrhythmogenicity.
Date: April 26, 2022
Creator: Jahed, Zeinab; Yang, Yang; Tsai, Ching-Ting; Foster, Ethan P.; McGuire, Allister F.; Yang, Huaxiao et al.
System: The UNT Digital Library