Evidence and reporting standards in N-of-1 medical studies: a systematic review (open access)

Evidence and reporting standards in N-of-1 medical studies: a systematic review

Article describes how authors examined publications of medical N-of-1 trials to examine whether they meet the evidence standards and the criteria for demonstrating evidence of a relation between an independent and an outcome variable per the What Works Clearinghouse (WWC) standards for SCEDs. The authors also examined the appropriateness of the data analytic techniques in the special context of N-of-1 designs.
Date: July 18, 2023
Creator: Batley, Prathiba Natesan; McClure, Erica B.; Brewer, Brandy; Contractor, Ateka A.; Batley, Nicholas John; Hedges, Larry Vernon et al.
System: The UNT Digital Library
Manipulating microRNA miR408 enhances both biomass yield and saccharification efficiency in poplar (open access)

Manipulating microRNA miR408 enhances both biomass yield and saccharification efficiency in poplar

Article describes how the conversion of lignocellulosic feedstocks to fermentable sugar for biofuel production is inefficient, and most strategies to enhance efficiency directly target lignin biosynthesis, with associated negative growth impacts. The authors demonstrate, for both laboratory-and field-grown plants, that expression of Pag-miR408 in poplar significantly enhances saccharification, with no requirement for acid-pretreatment, while promoting plant growth.
Date: July 18, 2023
Creator: Guo, Yayu; Wang, Shufang; Yu, Keji; Wang, Hou-Ling; Xu, Huimin; Song, Chengwei et al.
System: The UNT Digital Library