Inhibition of Very Long Chain Fatty Acids Synthesis Mediates PI3P Homeostasis at Endosomal Compartments (open access)

Inhibition of Very Long Chain Fatty Acids Synthesis Mediates PI3P Homeostasis at Endosomal Compartments

This article uses metazachlor, an inhibitor of VLCFA synthesis, to find that VLCFAs are involved in the TGN/MVB distribution of PI3P. This effect is independent from either synthesis of PI3P by PI3-kinase or degradation of PI(3,5)P2 into PI3P by the SUPPRESSOR OF ACTIN1 (SAC1) phosphatase. Results suggest that PI3P might be transferable from TGN to MVBs and that VLCFAs act in this process.
Date: August 6, 2021
Creator: Ito, Yoko; Esnay, Nicolas; Fougère, Louise; Platre, Matthieu Pierre; Cordelières, Fabrice; Jaillais, Yvon et al.
System: The UNT Digital Library
The Cluster Transfer Function of AtNEET Supports the Ferredoxin–Thioredoxin Network of Plant Cells (open access)

The Cluster Transfer Function of AtNEET Supports the Ferredoxin–Thioredoxin Network of Plant Cells

This article develops an inducible expression system to study AtNEET function in mature plants using a time-course proteomics approach. The authors report that the suppression of AtNEET cluster transfer function results in drastic changes in the expression of different members of the ferredoxin (Fd), Fd-thioredoxin (TRX) reductase (FTR), and TRX network of Arabidopsis, as well as in cytosolic cluster assembly proteins.
Date: August 6, 2022
Creator: Zandalinas, Sara I.; Song, Luhua; Nechushtai, Rachel; Mendoza-CĂłzatl, David & Mittler, Ron
System: The UNT Digital Library
Histological features of non-alcoholic fatty liver disease revealed in response to mixed vehicle emission exposure and consumption of a high-fat diet in wildtype C57Bl/6 male mice (open access)

Histological features of non-alcoholic fatty liver disease revealed in response to mixed vehicle emission exposure and consumption of a high-fat diet in wildtype C57Bl/6 male mice

Article describes how non-alcoholic fatty liver disease (NAFLD) is currently plaguing the population at pandemic proportions and is expected to become more prevalent over the next decade. The authors investigated the hypothesis that exposure to a mixture of gasoline and diesel engine emissions (MVE), coupled with the concurrent consumption of a HF diet, promotes the development of a NAFLD phenotype within the liver.
Date: June 6, 2023
Creator: Schneider, Leah J.; Santiago, Isabella; Johnson, Bailee; Stanley, Analana Hays; Penaredondo, Bea & Lund, Amie K.
System: The UNT Digital Library
Developmental programming of DNA methylation and gene expression patterns is associated with extreme cardiovascular tolerance to anoxia in the common snapping turtle (open access)

Developmental programming of DNA methylation and gene expression patterns is associated with extreme cardiovascular tolerance to anoxia in the common snapping turtle

This article explores DNA methylation's role in the regulation of gene expression in reptiles. Results show that embryonic hypoxia programs DNA methylation and gene expression patterns and that these changes are associated with enhanced cardiac anoxia tolerance in snapping turtles later in life.
Date: September 6, 2021
Creator: Ruhr, Ilan; Bierstedt, Jacob; Rhen, Turk; Das, Debojyoti; Singh, Sunil Kumar; Miller, Solielle et al.
System: The UNT Digital Library
Dual Mechanisms of Coniferyl Alcohol in Phenylpropanoid Pathway Regulation (open access)

Dual Mechanisms of Coniferyl Alcohol in Phenylpropanoid Pathway Regulation

This article reports that a major monomer unit of the lignin polymer can function as a signal molecule to trigger proteolysis of the enzyme L-phenylalanine ammonia-lyase, the entry point into the lignin biosynthetic pathway, and feedback regulate the expression levels of lignin biosynthetic genes.
Date: May 6, 2022
Creator: Guan, Mengling; Li, Changxuan; Shan, Xiaotong; Chen, Fang; Wang, Shufang; Dixon, R. A. et al.
System: The UNT Digital Library
A metabolomic platform to identify and quantify polyphenols in coffee and related species using liquid chromatography mass spectrometry (open access)

A metabolomic platform to identify and quantify polyphenols in coffee and related species using liquid chromatography mass spectrometry

Article describes how products of plant secondary metabolism, such as phenolic compounds, flavonoids, alkaloids, and hormones, play an important role in plant growth, development, stress resistance. The authors state that the overall goal of this study was to develop a high-throughput workflow to identify and quantify plant polyphenols.
Date: January 6, 2023
Creator: Castro-Moretti, Fernanda R.; Cocuron, Jean-Christophe; Castillo-Gonzalez, Humberto; Escudero-Leyva, Efrain; Chaverri, Priscila; Guerreiro-Filho, Oliveiro et al.
System: The UNT Digital Library
Editorial: Lipid metabolism and membrane structure in plant biotic interactions (open access)

Editorial: Lipid metabolism and membrane structure in plant biotic interactions

Article discusses how Lipid bilayers represent the interface between cells (or organelles) and their environment. Authors claim that this special topic brings together new reports on several of these lipid classes to shed light on the impacts of plant lipid metabolism and membrane organization on plant immunity.
Date: December 6, 2022
Creator: Goggin, Fiona L.; Shah, Jyoti & Gillaspy, Glenda
System: The UNT Digital Library
Fatty acid amide hydrolase and 9-lipoxygenase  modulate cotton seedling growth by ethanolamide  oxylipin levels (open access)

Fatty acid amide hydrolase and 9-lipoxygenase modulate cotton seedling growth by ethanolamide oxylipin levels

Article asserts that polyunsaturated N-acylethanolamines (NAEs) can be hydrolyzed by fatty acid amide hydrolase (FAAH) or oxidized by lipoxygenase (LOX). Altogether, the authors conclude that the growth of cotton seedlings involves fine-tuning of 9-NAE-HOD levels via FAAH-mediated hydrolysis and LOX-mediated production, expanding the mechanistic understanding of plant growth modulation by NAE oxylipins to a perennial crop species.
Date: December 6, 2022
Creator: Gaguancela-Arias, Omar; Aziz, Mina & Chapman, Kent Dean
System: The UNT Digital Library
Transcriptional Programs and Regulators Underlying Age-Dependent and Dark-Induced Senescence in Medicago truncatula (open access)

Transcriptional Programs and Regulators Underlying Age-Dependent and Dark-Induced Senescence in Medicago truncatula

Article presents a study that reveals the dynamics of transcriptomic responses to age- and dark-induced senescence in M. truncatula and identifies senescence-associated TFs that are attractive targets for future work to control senescence in forage legumes.
Date: May 6, 2022
Creator: Mahmood, Kashif; Torres-Jerez, Ivone; Krom, Nick; Liu, Wei & Udvardi, Michael K.
System: The UNT Digital Library