Detecting interdisciplinary semantic drift for knowledge organization based on normal cloud model (open access)

Detecting interdisciplinary semantic drift for knowledge organization based on normal cloud model

Article describes how, to reduce the conceptual ambiguity in interdisciplinary knowledge organization systems (KOSs) and enhance interdisciplinary KOS management, this paper proposes a framework for interdisciplinary semantic drift (ISD) detection based on the normal cloud model (NCM). The research indicates the meaning of an interdisciplinary concept will drift from the high KPE discipline to the low KPE discipline as long as interdisciplinary knowledge potential differences (KPD) exist between these two related disciplines.
Date: April 27, 2023
Creator: Wang, Zhongyi; Peng, Siyuan; Chen, Jiangping; Kapasule, Amoni G. & Chen, Haihua
System: The UNT Digital Library
A Remarkable Difference in Pharmacokinetics of Fluorinated Versus Iodinated Photosensitizers Derived from Chlorophyll-a and a Direct Correlation between the Tumor Uptake and Anti-Cancer Activity (open access)

A Remarkable Difference in Pharmacokinetics of Fluorinated Versus Iodinated Photosensitizers Derived from Chlorophyll-a and a Direct Correlation between the Tumor Uptake and Anti-Cancer Activity

Article says that to investigate and compare the pharmacokinetic profile and anti-cancer activity of fluorinated and iodinated photosensitizers (PSs), the 3-(1′-(o-fluorobenzyloxy)ethyl pyropheophorbide and the corresponding meta-(m-) and para (p-) fluorinated analogs (methyl esters and carboxylic acids) were synthesized. According to the authors, the nature of the delivery vehicle and tumor types showed a significant difference in uptake and long-term cure by photodynamic therapy (PDT), especially in the iodinated PS.
Date: April 27, 2023
Creator: Pandurang, Taur Prakash; Cacaccio, Joseph; Durrani, Farukh A.; Dukh, Mykhaylo; Alsaleh, Ajyal Z.; Sajjad, Munawwar et al.
System: The UNT Digital Library