Effects of an exogenous ketone ester using multi-omics in skeletal muscle of aging C57BL/6J male mice (open access)

Effects of an exogenous ketone ester using multi-omics in skeletal muscle of aging C57BL/6J male mice

Article shows that oral R,S-1,3, butanediol diacetoacetate (BD-AcAc2) consumption results in body weight loss or maintenance with moderate increases in circulating ketones. The purpose of this study was to determine if a diet consisting of 25% BD-AcAc2 (ketone ester, KE) would alter body composition, transcriptional regulation, the proteome, and the lipidome of skeletal muscle in aged mice.
Date: November 15, 2022
Creator: Roberts, Brandon M.; Deemer, Sarah E.; Smith Jr., Daniel L.; Mobley, James A.; Musi, Nicolas & Plaisance, Eric P.
System: The UNT Digital Library