Benchmarking Metagenomic Classifiers on Simulated Ancient and Modern Metagenomic Data (open access)

Benchmarking Metagenomic Classifiers on Simulated Ancient and Modern Metagenomic Data

Article describes how taxonomic profiling of ancient metagenomic samples is challenging due to the accumulation of specific damage patterns on DNA over time. The authors performed a comprehensive evaluation on simulated metagenomes representing human dental calculus microbiome, with the level of DNA damage successively raised to mimic modern to ancient metagenomes.
Date: October 2, 2023
Creator: Pusadkar, Vaidehi & Azad, Rajeev K.
System: The UNT Digital Library