A Review of Rehabilitative and Assistive Technologies for Upper-Body Exoskeletal Devices (open access)

A Review of Rehabilitative and Assistive Technologies for Upper-Body Exoskeletal Devices

Authors state that this journal review article focuses on the use of assistive and rehabilitative exoskeletons as a new opportunity for individuals with diminished mobility. Overall, this article serves as a valuable resource for individuals working in the field of assistive and rehabilitative exoskeletons, providing insight into the state of the art and potential areas for improvement.
Date: April 20, 2023
Creator: Hays, Emilly; Slayton, Jack; Tejeda-Godinez, Gary; Carney, Emily; Cruz, Kobe; Exley, Trevor et al.
System: The UNT Digital Library
Light-Controlled Cell–Cell Assembly Using Photocaged Oligonucleotides (open access)

Light-Controlled Cell–Cell Assembly Using Photocaged Oligonucleotides

Article asserts that while techniques that allow one to control the arrangement of cells and direct contact between different cell types have been developed that expand upon simple co-culture methods, specific control over heterojunctions that form between cells is not easily accomplished with current methods, such as 3D cell-printing. In this article, DNA-mediated cell interactions are combined with cell-compatible photolithographic approaches to control cell assembly.
Date: May 23, 2023
Creator: Mathis, Katelyn; Kohon, Agia Ibnat; Black, Stephen & Meckes, Brian
System: The UNT Digital Library
Harnessing nanofiber alignment and pore size to promote stem cell self-renewal and differentiation (open access)

Harnessing nanofiber alignment and pore size to promote stem cell self-renewal and differentiation

Article describes how stem cell therapy holds immense potential for regenerative medicine, but its applications are limited due to the loss of pluripotency during in vitro expansion. This study reveals that the arrangement of electrospun fibers aligns with the distribution and strength of the electric field through both experimentation and simulation.
Date: July 25, 2023
Creator: Wei, Qiang; Blake, Laurence; Liu, Jiafeng; Man, Kun; Liang, Cindy; Teoh, Alexandra et al.
System: The UNT Digital Library
Suppression of the antitumoral activity of natural killer cells under indirect coculture with cancer-associated fibroblasts in a pancreatic TIME-on-chip model (open access)

Suppression of the antitumoral activity of natural killer cells under indirect coculture with cancer-associated fibroblasts in a pancreatic TIME-on-chip model

Article describes how recently, natural killer cells emerged as a treatment option for various solid tumors. The effect of activated pancreatic stellate cells on natural killer cell-mediated anticancer efficacy under three-dimensional coculture conditions was investigated.
Date: September 27, 2023
Creator: Kim, Hyun-Ah; Kim, Hyunsoo; Nam, Min-Kyung; Park, Jong Kook; Lee, Moo-Yeal; Chung, Seok et al.
System: The UNT Digital Library
Nanotopographical Cues Tune the Therapeutic Potential of Extracellular Vesicles for the Treatment of Aged Skeletal Muscle Injuries (open access)

Nanotopographical Cues Tune the Therapeutic Potential of Extracellular Vesicles for the Treatment of Aged Skeletal Muscle Injuries

Article describes how skeletal muscle regeneration relies on the tightly temporally regulated lineage progression of muscle stem/progenitor cells (MPCs) from activation to proliferation and finally, differentiation. The authors developed an engineering strategy to tune the therapeutic potential of EVs using nanotopographical cues.
Date: October 5, 2023
Creator: Wang, Kai; Frey, Nolan; Garcia, Andres C.; Man, Kun; Yang, Yong; Gualerzi, Alice et al.
System: The UNT Digital Library
Multifaceted Shape Memory Polymer Technology for Biomedical Application: Combining Self-Softening and Stretchability Properties (open access)

Multifaceted Shape Memory Polymer Technology for Biomedical Application: Combining Self-Softening and Stretchability Properties

Article describes how thiol-ene polymers are a promising class of biomaterials with a wide range of potential applications, including organs-on-a-chip, microfluidics, drug delivery, and wound healing. This study investigated the incorporation of di-acrylate chain extenders to improve the stretchability and conformability of those flexible thiol-ene polymers.
Date: October 25, 2023
Creator: Chitrakar, Chandani; Torres, Marc Anthony; Rocha-Flores, Pedro Emanuel; Hu, Qichan & Ecker, Melanie
System: The UNT Digital Library
Detergent-Based Decellularization for Anisotropic Cardiac-Specific Extracellular Matrix Scaffold Generation (open access)

Detergent-Based Decellularization for Anisotropic Cardiac-Specific Extracellular Matrix Scaffold Generation

Article describes how cell-derived extracellular matrix has become increasingly popular in tissue engineering applications due to its ability to provide tailored signals for desirable cellular responses. The objective of this study was to assess the efficacy of two detergent-based decellularization methods: a combination of ethylenediaminetetraacetic acid and sodium dodecyl sulfate and a combination of sodium deoxycholate and deoxyribonuclease.
Date: November 17, 2023
Creator: Chen, Te-An; Sharma, Dhavan; Jia, Wenkai; Ha, Donggi; Man, Kun; Zhang, Jianhua et al.
System: The UNT Digital Library
Surface Nanostructures Enhanced Biocompatibility and Osteoinductivity of laser-Additively Manufactured CoCrMo Alloys (open access)

Surface Nanostructures Enhanced Biocompatibility and Osteoinductivity of laser-Additively Manufactured CoCrMo Alloys

Article describes how cobalt–chromium–molybdenum (CoCrMo) alloys are widely used in orthopedic implants due to their excellent corrosion and wear resistance and superior mechanical properties. In this study, the authors prepared CoCrMo alloys with surface nanostructures of various aspect ratios (AR) using laser-directed energy deposition (L-DED) and biocorrosion.
Date: December 6, 2023
Creator: Man, Kun; Mazumder, Sangram; Dahotre, Narendra B. & Yang, Yong
System: The UNT Digital Library
Mesenchymal stem cells aligned and stretched in self-assembling peptide hydrogels (open access)

Mesenchymal stem cells aligned and stretched in self-assembling peptide hydrogels

Article describes how the presented research highlights a novel approach using fmoc-protected peptide hydrogels for the encapsulation and stretching of mesenchymal stem cells. This study utilized a custom mechanical stretching device with a PDMS chamber to stretch human mesenchymal stem cells encapsulated in Fmoc hydrogels.
Date: December 19, 2023
Creator: Fouladgar, Farzaneh; Moslabeh, Forough G. Z.; Kasani, Yashesh V.; Rogozinski, Nick; Torres, Marc; Ecker, Melanie et al.
System: The UNT Digital Library