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Brain Delivery of Thyrotropin-Releasing Hormone via a Novel Prodrug Approach
Using thyrotropin-releasing hormone (TRH) as a model, paper explores whether synergistic combination of lipoamino acid(s) and a linker cleaved by prolyl oligopeptidase (POP) can be used as a promoiety for prodrug design for the preferential brain delivery of the peptide.
Date:
July 18, 2019
Creator:
Prokai-Tatrai, Katalin; De La Cruz, Daniel L.; Nguyen, Vien; Ross, Benjamin P.; Toth, Istvan & Prókai, László, 1958-
System:
The UNT Digital Library
Structural design optimization of knee replacement implants for Additive Manufacturing
Article describes study focused on proposing a setup of a proper methodology for the rapid development of optimized surgical implants.
Date:
July 18, 2019
Creator:
Peto, Marinela; Ramírez-Cedillo, Erick; Hernández, Adriana & Siller Carrillo, Héctor Rafael
System:
The UNT Digital Library