SEIPIN Isoforms Interact with the Membrane-Tethering Protein VAP27-1 for Lipid Droplet Formation (open access)

SEIPIN Isoforms Interact with the Membrane-Tethering Protein VAP27-1 for Lipid Droplet Formation

Article demonstrating that part of the function of two SEIPIN isoforms in Arabidopsis (Arabidopsis thaliana), AtSEIPIN2 and AtSEIPIN3, may depend on their interaction with the vesicle-associated membrane protein (VAMP)–associated protein (VAP) family member AtVAP27-1. The authors used a combination of biochemical, cell biology, and genetics approaches to show that AtVAP27-1 interacts with the N termini of AtSEIPIN2 and AtSEIPIN3 and likely supports the normal formation of LDs. This insight indicates that the ER membrane tethering machinery in plant cells could play a role with select SEIPIN isoforms in LD biogenesis at the ER, and additional experimental evidence in Saccharomyces cerevisiae supports the possibility that this interaction may be important in other eukaryotic systems.
Date: July 20, 2020
Creator: Greer, Michael Scott; Cai, Yingqi; Gidda, Satinder K.; Esnay, Nicolas; Kretzschmar, Franziska K.; Seay, Damien C. et al.
System: The UNT Digital Library
Whole-genome survey reveals extensive variation in genetic diversity and inbreeding levels among peregrine falcon subspecies (open access)

Whole-genome survey reveals extensive variation in genetic diversity and inbreeding levels among peregrine falcon subspecies

Article describes how, in efforts to prevent extinction, resource managers are often tasked with increasing genetic diversity in a population of concern to prevent inbreeding depression or improve adaptive potential in a changing environment. The authors used whole-genome resequencing to generate over two million single nucleotide polymorphisms (SNPs) from multiple individuals of all peregrine falcon subspecies.
Date: July 20, 2023
Creator: Johnson, Jeff A.; Athrey, Giridhar; Anderson, Clifford M.; Bell, Douglas A.; Dixon, Andrew; Kumazawa, Yoshinori et al.
System: The UNT Digital Library
Computational criteria for establishing reflex from plasticity to hardwiring (open access)

Computational criteria for establishing reflex from plasticity to hardwiring

Article accompanying a poster for the 2010 Computational Neuroscience Annual Meeting. This article discusses computational criteria for establishing reflex from plasticity to hardwiring.
Date: July 20, 2010
Creator: Tam, Nicoladie D.
System: The UNT Digital Library