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480 Matching Results
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Theranostic Small-Molecule Prodrug Conjugates for Targeted Delivery and Controlled Release of Toll-like Receptor 7 Agonists
This article presents a novel class of chemically identical theranostic small-molecule prodrug conjugates (T-SMPDCs), [¹⁸/¹⁹F]F-TZ(PSMA)-LEGU-TLR7, for PSMA-targeted delivery and controlled release of toll-like receptor 7 (TLR7) agonists to elicit de novo immune response for cancer immunotherapy. The proof-of-concept biological evaluation presented demonstrates the potential of T-SMPDCs for cancer immunomodulatory therapies.
Date:
June 28, 2022
Creator:
Debnath, Sashi; Hao, Guiyang; Guan, Bing; Thapa, Pawan; Hao, Justin; Hammers, Hans et al.
Object Type:
Article
System:
The UNT Digital Library
Nanomagnet-facilitated pharmaco-compatibility for cancer diagnostics: Underlying risks and the emergence of ultrasmall nanomagnets
Article summarizes various progressive aspects of nanomagnets pertaining to their production with an emphasis on sustainable biomimetic approaches, particularly cancer therapy.
Date:
June 27, 2022
Creator:
Parimi, Divya S.; Gupta, Yamini; Marpu, Sreekar; Bhatt, Chandra S.; Bollu, Tharun K. & Suresh, Anil K.
Object Type:
Article
System:
The UNT Digital Library
Moving the End of Term Web Archive to the Cloud to Encourage Research Use and Reuse
Presentation given at the 2022 Web Archiving and Digital Libraries Virtual Workshop, in conjunction with the Joint Conference on Digital Libraries (JCDL), on June 24, 2022. This presentation discusses the End of Term (EOT) Web Archive project and process of organizing, staging, processing, and moving these collections into the Amazon cloud.
Date:
June 24, 2022
Creator:
Phillips, Mark Edward & Alam, Sawood
Object Type:
Presentation
System:
The UNT Digital Library
Moving the End of Term Web Archive to the Cloud to Encourage Research Use and Reuse
Short paper presented at the 2022 Web Archiving and Digital Libraries Virtual Workshop, in conjunction with the Joint Conference on Digital Libraries (JCDL), on June 24, 2022. The paper discusses the End of Term (EOT) Web Archive project and process of organizing, staging, processing, and moving these collections into the Amazon cloud.
Date:
June 24, 2022
Creator:
Phillips, Mark Edward & Alam, Sawood
Object Type:
Paper
System:
The UNT Digital Library
Library Computing Services in Rural Texas during the COVID-19 Pandemic
Article analyzing the 2020 Texas Public Library Statistics and a portion of the 2019 and 2018 data. It examined various services from libraries located in the areas with a population of less than 5,000. This is the Accepted Manuscript version of a published article.
Date:
June 23, 2022
Creator:
Du, Yunfei
Object Type:
Article
System:
The UNT Digital Library
Sustaining Human Nutrition in an Increasingly Urban World
This article proposes an urban nutrition (UN) extension to the previously published urban ecological economic system. The proposed extension can be used by decision makers worldwide to evaluate how landscape configurations and agricultural production systems affect the nutritional needs of the local population while fostering sustainable practices.
Date:
June 22, 2022
Creator:
Torres, Angélica Valencia; Tiwari, Chetan & Atkinson, Samuel F.
Object Type:
Article
System:
The UNT Digital Library
Probabilistic Seismic Assessment of CoSPSW Structures Using Fragility Functions
This article presents a study on the probabilistic assessment of the seismic performance and vulnerability of corrugated steel plate shear walls (CoSPSWs) using fragility functions.
Date:
June 18, 2022
Creator:
Tan, Zhilun; Zhao, Quihong; Zhao, Yu & Yu, Cheng
Object Type:
Article
System:
The UNT Digital Library
Stabilized anode-electrolyte interfaces via Cs4Pb(Cl/Br/I)6 perovskite crystal based glass-ceramics for fast and long cycle-life lithium ion batteries
Article is a study that designs a smart anode/liquid electrolyte interface for high energy density batteries that present large specific capacity retentions.
Date:
June 17, 2022
Creator:
Xie, Wenqing; Cao, Jianghang; Li, Panpan; Fan, Meiqiang; Xu, Shiqing; Du, Jincheng et al.
Object Type:
Article
System:
The UNT Digital Library
With great power comes great responsibility: Libraries & publishers providing accessible content
Article reporting on a panel session of the same title from the Charleston Conference 2021. The panelists revealed how their organizations implemented accessibility initiatives that provide print disabled users with greater access to online content, and the author provides an overview of their discussion.
Date:
June 16, 2022
Creator:
Dawson, Jill
Object Type:
Article
System:
The UNT Digital Library
Transcriptome of Endophyte-Positive and Endophyte-Free Tall Fescue Under Field Stresses
This article is a study that represents the first transcriptome analysis of E+ and E− Texoma tall fescue under freezing and chilling temperatures in the natural field environment.
Date:
June 14, 2022
Creator:
Islam, Shofiqul; Krom, Nick; Kwon, Taegun; Li, Guifen & Saha, Malay
Object Type:
Article
System:
The UNT Digital Library
Empirical Studies on Effect of Low-Level Laser Treatment on Glioblastoma Multiforme in Combination with Ag-PMMA-PAA Nanoparticles: Paired Red Region Optical-Property Treatment Platform
This article investigates low-level laser therapy for brain tumor treatment. The results provide evidence that the paired optical-driven agents provide a tunable platform that can generate significant U251 cell death increase.
Date:
June 13, 2022
Creator:
Atluri, Rohini; Korir, Daniel K.; Choi, Tae-Youl & Simmons, Denise Perry
Object Type:
Article
System:
The UNT Digital Library
The flexibility of proanthocyanidin biosynthesis in plants
Article presents research that explores proanthocyanidin (PA) biosynthesis routes in plants. The data suggests that different species have evolved different routes for PA biosynthesis.
Date:
June 13, 2022
Creator:
Lu, Nan; Jun, Ji Hyung; Liu, Chenggang & Dixon, R. A.
Object Type:
Article
System:
The UNT Digital Library
Thymus Functionality Needs More Than a Few TECs
Article is a review exploring the contributions of the many stromal cell types participating in the formation, expansion, and contraction of the thymus under normal and pathophysiological processes. Such information will better inform approaches for restoring thymus functionality, including thymus organoid technologies, beneficial when an individuals’ own tissue is congenitally, clinically, or accidentally rendered non-functional.
Date:
June 10, 2022
Creator:
Bhalla, Pratibha; Su, Dong-Ming & van Oers, Nicolai S. C.
Object Type:
Article
System:
The UNT Digital Library
Detecting Covid-19 chaos driven phishing/malicious URL attacks by a fuzzy logic and data mining based intelligence system
Article analyses the impact of Covid-19 on various cyber-security related aspects.
Date:
June 7, 2022
Creator:
Zahra, Syed Rameem; Chishti, Mohammad Ahsan; Baba, Asif Iqbal & Wu, Fan
Object Type:
Article
System:
The UNT Digital Library
Proteomic and metabolic disturbances in lignin-modified Brachypodium distachyon
This article investigates global metabolic responses to lignin pathway perturbations in the model grass Brachypodium distachyon using a systems biology approach.
Date:
June 7, 2022
Creator:
Barros, Jaime; Shrestha, Him K.; Serrani-Yarce, Juan C.; Engle, Nancy L.; Abraham, Paul E.; Tschaplinski, Timothy J. et al.
Object Type:
Article
System:
The UNT Digital Library
Biomimics of [FeFe]-hydrogenases incorporating redox-active ligands: synthesis, redox properties and spectroelectrochemistry of diiron-dithiolate complexes with ferrocenyl-diphosphines as Fe4S4 surrogates
Article prepares and characterizes a small series of new [FeFe]-ase biomimics which contain a ferrocenyl diphosphine as a surrogate for the Fe₄S₄ moiety in the H-cluster of the enzyme. Mechanistic details of both proton reduction and H₂ oxidation have been studied by DFT allowing speculative reaction schemes to be developed.
Date:
June 6, 2022
Creator:
Orton, Georgia R. F.; Ghosh, Shishir; Alker, Lucy; Sarker, Jagodish C.; Pugh, David; Richmond, Michael G. et al.
Object Type:
Article
System:
The UNT Digital Library
Exploring Changes in Quasar Spectral Energy Distributions across C iv Parameter Space
This article examines the UV/X-ray properties of 1378 quasars in order to link empirical correlations to theoretical models of the physical mechanisms dominating quasars as a function of mass and accretion rate.
Date:
June 6, 2022
Creator:
Rivera, Angelica B.; Richards, Gordon T.; Gallagher, Sarah C.; McCaffrey, Trevor V.; Rankine, Amy L.; Hewett, Paul C. et al.
Object Type:
Article
System:
The UNT Digital Library
Laser Diffraction Zones and Spots from Three-Dimensional Graded Photonic Super-Crystals and Moiré Photonic Crystals
This article reports the holographic fabrication of three types of 3D graded photonic super-crystals (GPSCs) through nine beam interferences and their characteristic diffraction patterns.
Date:
June 3, 2022
Creator:
Hurley, Noah; Kamau, Steve; Alnasser, Khadijah; Philipose, Usha; Cui, Jingbiao & Lin, Yuankun
Object Type:
Article
System:
The UNT Digital Library
Application of Big Data Analytics in Precision Medicine: Lesson for Ethiopia
Precision medicine is an emerging approach for disease treatment and prevention that considers individual variability in genes, environment, and lifestyle for each person. Big data analytics (BDA) using cutting-edge technologies helps to design models that can diagnose, treat and predict diseases. In Ethiopia, healthcare service delivery faces many challenges specifically in relation to prescribing the right medicine to the right patient at the right time. Thus, patients face challenges ranging from staying on treatment plans longer, and then leaving treatment, and finally dying of complications. Therefore, the aim of this paper is to explore the trends, challenges, and opportunities of applying BDA in precision medicine globally and take lessons for Ethiopia through a systematic literature review of 19 peer reviewed articles from five databases. The findings indicated that cancer in general, epilepsy, and systemic diseases altogether are areas currently getting big attention. The challenges are attributed to the nature of health data, failure in collaboration for data sharing, ethical and legal issues, interoperability of systems, poor knowledge skills and culture, and poor infrastructure. Development of modern technologies, experimental technologies and methods, cloud computing, Internet of Things, social networks and Ethiopia’s government initiative to promote private technological firms could be an …
Date:
June 2022
Creator:
Woldemariam, Misganaw Tadesse & Alemneh, Daniel Gelaw
Object Type:
Text
System:
The UNT Digital Library
Changing Landscape of Scholarly Communications: Open Access
The 17th International Conference on Knowledge Management was held in the historic city of Potsdam, Germany. Since the conference was among the first post-pandemic face to face conferences, the overall theme of the 17th edition of the ICKM conference rightly focused on “Knowledge, Uncertainty and Risks: From individual to global scale” at different levels of analysis and agency. This document highlighted one of the panels and the panelists argue that open access to scholarly knowledge production should be the modus operandi in the time and age we live in. Open access to knowledge is critical not just to accelerate advances in finding solutions to societal issues, but also to meet the growing expectations around higher education institutions’ social responsibilities in times of uncertainties.
Date:
June 2022
Creator:
Alemneh, Daniel Gelaw; Hawamdeh, Suliman M.; Fourie, Ina; Rorissa, Abebe; Ford, Angela & Assefa, Shimelis
Object Type:
Book
System:
The UNT Digital Library
Increasing Information Certainty for Post-Traumatic Growth
Trauma, and its associated effects, can be conceptualized as a period of information uncertainty. The natural psychological response to trauma is a period of post-traumatic stress. Trauma occurs when an existing knowledge base has been challenged. Any event that challenges important components of an individual’s assumptive world is said to be traumatic. This post-traumatic period is akin to many theories and concepts in information science including uncertainty reduction, Everyday Life Information Seeking, Sensemaking Theory, Making Meaning and Anomalous States of Knowledge. One possible outcome after the post- traumatic period is post-traumatic growth. Researchers agree post-traumatic growth primarily occurs across one or more of the following domains: personal strength, new possibilities, relating to others, appreciation of life and spiritual change. That is, people affected by trauma tend to grow when they find new or additional paths of information certainty.
Date:
June 2022
Creator:
Bank, Nicole & Allen, Jeff M., 1968-
Object Type:
Text
System:
The UNT Digital Library
An Interactive Web-Based Dashboard to Examine Trending Topics: Application to Financial Journals
Understanding trends is helpful to identify future behaviors in the field, and the roles of people, places, and institutions in setting those trends. Although traditional clustering strategies can group articles into topics, these techniques do not focus on topics over limited timescales; additionally, even when articles are grouped, the generated results are extensive and difficult to navigate. To address these concerns, we create an interactive dashboard that helps an expert in the field to better understand and quantify trends in their area of research. Trend detection is performed using the time-biased document clustering introduced in Behpour et al. (2021) study. The developed and freely available web application enables users to detect well defined trending topics in financial journals by experimenting with various levels of temporal bias - from detecting short-timescale trends to allowing those trends to spread over longer times. Experts can readily drill down into the identified topics to understand their meaning through keywords, example articles, and time range. Overall, the interactive dashboard will allow experts in the field to sift through the vast literature to identify the concepts, people, places, and institutions most critical to the field.
Date:
June 2022
Creator:
Phan, Ngoc; Madali, Nayana Pampapura; Behpour, Sahar & Xiao, Ting
Object Type:
Text
System:
The UNT Digital Library
Metadata Practices of Academic Libraries in Kuwait, Oman, and Qatar: Current State, Risks, and Perspectives for Knowledge Management
Developing, implementing, and managing metadata is crucial to successful knowledge management, and academic libraries have traditionally played a central role in these activities. The Arabian Gulf countries are underrepresented in the existing research into library metadata practices. This exploratory study used semi-structured interviews of metadata managers at 8 universities with the goal of developing understanding of the current state of metadata practices, including descriptive cataloging, identity management, and knowledge organization in academic libraries of three Arabian Gulf countries (Kuwait, Oman, and Qatar), as well as potential future developments to facilitate discovery of resources. Findings provide insights into this previously under-researched area and contribute to understanding of knowledge management and risks on a global scale.
Date:
June 2022
Creator:
Zavalina, Oksana & Aljalahmah, Saleh
Object Type:
Text
System:
The UNT Digital Library
Prediction of Concrete Bridge Deck Condition Ratting Based on Climate Data in Addition to Bridge Data: Five States as a Case Study
Evaluating the impact of learning from climate data, in addition to bridge data, on the performance of concrete deck condition rating prediction is critical for identifying the right data needed to enhance bridge maintenance decision making. Few studies have considered such an evaluation and utilized a small size of samples that prevent revealing the knowledge hidden within the big size of data. Although, such evaluation over big data seems quite necessary, class imbalance problem makes it challenging. To alleviate such a problem, five states, including Alabama, Iowa, New York, Pennsylvania, and South Carolina, were selected as the case study. Not only are the states located in three different climatically consistent regions defined by the National Ocean and Atmospheric Administration (NOAA), but also their concrete deck conditions ratings are somewhat balanced. To conduct the evaluation, this research developed the bridge data set pertaining to 56,288 bridges across the afore-mentioned states through employing the GIS technology. The bridge data set contains bridge data derived from National Bridge Inventory (NBI), and climate data derived from Parameter-elevation Relationships on Independent Slopes Model (PRISM) climate maps and NOAA. Then, two machine learning algorithms, including random forest and GBM, were trained - with and without climate …
Date:
June 2022
Creator:
Fard, Fariba
Object Type:
Text
System:
The UNT Digital Library