Pulmonary Carcinoid Surface Receptor Modulation Using Histone Deacetylase Inhibitors (open access)

Pulmonary Carcinoid Surface Receptor Modulation Using Histone Deacetylase Inhibitors

Study describes the use of a non-cytotoxic dose of histone deacetylase (HDAC) inhibitors to induce pulmonary carcinoid somatostatin receptor subtype 2 (SSTR2) expression to diagnose pulmonary carcinoids.
Date: June 3, 2019
Creator: Guenter, Rachael E.; Aweda, Tolulope; Matos, Danilea M. Carmona; Whitt, Jason; Chang, Alexander W.; Cheng, Eric Y. et al.
System: The UNT Digital Library
Role of the Ubiquitin Proteasome System (UPS) in the HIV-1 Life Cycle (open access)

Role of the Ubiquitin Proteasome System (UPS) in the HIV-1 Life Cycle

This article is an overview the interplay between HIV-1 viral and cellular proteins for restrictions/competitions for proliferation of the virus in the infected cell, which could open a new avenue for the development of therapeutics against HIV-1 via targeting a specific step of the proteasome degradation pathway during the HIV-1 life cycle.
Date: June 19, 2019
Creator: Rojas, Vivian K. & Park, In-Woo
System: The UNT Digital Library
Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes-5 (open access)

Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes-5

The article is part of a series of Editorials published biannually that highlights a number of recently published articles that describe crucial findings.
Date: June 30, 2019
Creator: Mangoni, Arduino A; Vanden Eynde, Jean Jacques; Jampilek, Josef; Hadjipavlou-Litina, Dimitra; Liu, Hong; Reynisson, Jóhannes et al.
System: The UNT Digital Library