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A cytochrome P450 monooxygenase commonly used for negative selection in transgenic plants causes growth anomalies by disrupting brassinosteroid signaling
Article on a cytochrome P450 monooxygenase commonly used for negative selection in transgenic plants causing growth anomalies by disrupting brassinosteroid signaling.
Date:
April 15, 2011
Creator:
Dasgupta, Kasturi; Ganesan, Savita; Manivasagam, Sindhu & Ayre, Brian G.
System:
The UNT Digital Library
Structural Consideration in Designing Organotin Polyethers to Arrest the Growth of Breast Cancer Cells In Vitro
The article looks at antitumor activity using a matched pair of cell lines MDA-MB-231 cells that are estrogen-independent, estrogen receptor negative and MCF-7 cells, a cell line that is estrogen receptor (ER) positive. Those polyethers that contained a O-phenyl unit were able to significantly inhibit the non-estrogen sensitive cell line but were much less effective against the estrogen sensitive cell line; that is, the human breast cancer cell line MDA-MB-231 showed better test results for polymers derived from diols containing the O-phenyl moiety than the breast cancer cell line MCF-7, a well-characterized estrogen receptor positive control cell line.
Date:
April 15, 2011
Creator:
Carraher, Charles E., Jr.; Roner, Michael R.; Shahi, Kimberly & Barot, Girish
System:
The UNT Digital Library
Traffic generated emissions alter the lung microbiota by promoting the expansion of Proteobacteria in C57Bl/6 mice placed on a high-fat diet
Article investigating exposure to traffic-generated emissions and the potential to alter lung microbiota and immune defenses. Results show that the combined effects of ME and HF diet result in decreased immune surveillance and lung bacterial dysbiosis, which is of significance in lung diseases.
Date:
April 15, 2021
Creator:
Daniel, Sarah; Pusadkar, Vaidehi; McDonald, Jacob D.; Mirpuri, Julie; Azad, Rajeev K.; Goven, Art et al.
System:
The UNT Digital Library
Vehicle emissions-exposure alters expression of systemic and tissue-specific components of the renin-angiotensin system and promotes outcomes associated with cardiovascular disease and obesity in wild-type C57BL/6 male mice
This article investigates the hypothesis that exposure to engine emissions increases systemic and local adipocyte RAS signaling, promoting the expression of factors involved in cardiovascular disease and obesity.
Date:
April 15, 2021
Creator:
Phipps, Benjamin L.; Suwannasual, Usa; Lucero, JoAnn; Mitchell, Nicholas A. & Lund, Amie K.
System:
The UNT Digital Library