The Emerging Roles of mTORC1 in Macromanaging Autophagy (open access)

The Emerging Roles of mTORC1 in Macromanaging Autophagy

Review critically analyzes current literature to provide an integrated view of how rapamycin complex 1 (mTORC1) regulates various steps of the autophagy process.
Date: September 24, 2019
Creator: Dossou, Akpedje S. & Basu, Alakananda
System: The UNT Digital Library
HIV-1 Impairment via UBE3A and HIV-1 Nef Interactions Utilizing the Ubiquitin Proteasome System (open access)

HIV-1 Impairment via UBE3A and HIV-1 Nef Interactions Utilizing the Ubiquitin Proteasome System

Study examines the interaction between a key pathogenic HIV-1 viral protein, Nef, and ubiquitin (Ub)-protein ligase E3A (UBE3A).
Date: November 27, 2019
Creator: Pyeon, Dohun; Rojas, Vivian K.; Price, Lenore; Kim, Seongcheol; Singh, Meharvan & Park, In-Woo
System: The UNT Digital Library
Distinct Roles of mTOR Targets S6K1 and S6K2 in Breast Cancer (open access)

Distinct Roles of mTOR Targets S6K1 and S6K2 in Breast Cancer

The purpose of this article is to compare and contrast the expression, structure, regulation and function of these two S6K homologs in breast cancer.
Date: February 11, 2020
Creator: Sridharan, Savitha & Basu, Alakananda
System: The UNT Digital Library