The Human Genome Initiative is a worldwide research effort with the goal of analyzing the structure of human DNA and determining the location of the estimated 100,000 human genes. In parallel with this effort, the DNA of a set of model organisms will be studied to provide the comparative information necessary for understanding the functioning of the human genome. The information generated by the human genome project is expected to be the source book for biomedical science in the 21st century and will by of immense benefit to the field of medicine. It will help us to understand and eventually treat many of the more than 4000 genetic diseases that affect mankind, as well as the many multifactorial diseases in which genetic predisposition plays an important role. A centrally coordinated project focused on specific objectives is believed to be the most efficient and least expensive way of obtaining this information. The basic data produced will be collected in electronic databases that will make the information readily accessible on convenient form to all who need it. This report describes the plans for the U.S. human genome project and updates those originally prepared by the Office of Technology Assessment (OTA) and the …

This report presents a five year plan for the laboratory. This plan takes advantage of the technical strengths of the lab and its staff to address issues of concern to the nation on a scope much broader than Sandia`s original mission, while maintaining the general integrity of the laboratory. The plan proposes initiatives in a number of technologies which overlap the needs of its customers and the strengths of its staff. They include: advanced manufacturing technology; electronics; information and computational technology; transportation energy technology and infrastructure; environmental technology; energy research and technology development; biomedical systems engineering; and post-cold war defense imperatives.

A team of senior managers from across the US Nuclear Regulatory Commission (NRC), working with the Office of Information Resources Management (IRM), has completed an NRC Strategic Information Technology (IT) Plan. The Plan addresses three major areas: (1) IT Program Management, (2) IT Infrastructure, and (3) Information and Applications Management. Key recommendations call for accelerating the replacement of Agency workstations, implementing a new document management system, applying business process reengineering to selected Agency work processes, and establishing an Information Technology Council to advise the Director of IRM.

The Waste Isolation Division (WID) is committed to providing good stewardship for the capital assets under its operational and physical control. To achieve this goal, the WID has developed the Capital Asset Implementation Plan (CAIP) to continue to implement for FY95 Department of Energy (DOE) Order 4320.2A, Capital Asset Management Process (CAMP). The Order provides policy and elements needed to establish a credible, consistent, auditable, and technically sound process for the DOE to forecast, plan, and budget for capital assets on a functional unit level. The objective of the WIPP CAMP program is to meet the goals of DOE Order 4320.2A in the most effective and efficient manner possible in support of the Waste Isolation Pilot Plant (WIPP) mission. As a result, this CAIP provides a way to implement the CAMP Program using a graded approach. Continued implementation will be accomplished by improving the existing process, and establishing future goals to promote growth for the CAMP Program. The CAIP is issued annually by the WID with quarterly progress reports submitted to the DOE. This document describes the current-year program staffing, roles, responsibilities, funding, and near-term milestones. In addition, the results of past goals are discussed.

This is an internal DOE Geothermal Program planning and control document. The Five Year Plans and Multi-Year Plans usually included more detailed rationales and projections than other similar reports. Many of these reports were issued only in draft form. (DJE 2005)

This is an internal DOE Geothermal Program planning and control document. The Five Year Plans and Multi-Year Plans usually included more detailed rationales and projections than other similar reports. Many of these reports were issued only in draft form. (DJE 2005)

This administrative report of the Department of Energy is dated December 21, 1990. It is marked ''DRAFT'' as were many of this type of report, most of which were never made ''Final''. It provides contextual elements for program planning, and covers research on Hydrothermal, Geopressured Geothermal, Hot Dry Rock, and Magma Energy systems. (DJE 2005)

This report contains the project summary, as well as the financial summary for the Mixed Waste Management Facility at Lawrence Livermore National Laboratory. Detailed accomplishments and milestone status are reported in the Task Summaries. The major accomplishments during this reporting period are included the following areas: preliminary design; systems integration; briefings for the Environmental Programs Scientific Advisory Committee; integrated cost/scheduling estimating system; feed preparation; mediated electrochemical oxidation; and molten salt oxidation.

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This report describes progress made during the previous year in experimental and theoretical investigations of high- and low-energy collisions involving multiply charged ions. The work from previous years has resulted in publication of 27 papers in refereed journals during the last twelve months. This report includes a list of published manuscripts as well as lists of abstracts for five different conferences/workshops during the grant period.

The DOE Site Operator Program was initially established to meet the requirements of the Electric and Hybrid Vehicle Research, Development, and Demonstration Act of 1976. The Program has since evolved in response to new legislation and interests. Its mission now includes three ma or activity categories: (1) Advancement of Electric Vehicle (EV) technologies, (2) Development of infrastructure elements needed to support significant EV use, and (3) Increasing public awareness and acceptance of EVs. The 13 Program participants, their geographic locations, and the principal thrusts of their efforts are identified in Table ES-1. The EV inventories of each participant are summarized in Table ES-2.

The Buried Waste Integrated Demonstration (BWID) is a program funded by the U.S. Department of Energy Office of Technology Development. BWID supports the applied research, development, demonstration, testing, and evaluation of a suite of advanced technologies that together form a comprehensive remediation system for the effective and efficient remediation of buried waste. The FY-95 effort will fund 24 technologies in five areas of buried waste site remediation: site characterization, waste characterization, retrieval, treatment, and containment/stabilization. Ten of these technologies will take part in the integrated field demonstration that will take place at the Idaho National Engineering Laboratory (INEL) facilities in the summer of 1995. This document is the basic operational planning document for deployment of all BWID projects funded in FY-95. Discussed in this document are the BWID preparations for the INEL integrated field demonstration, INEL research and development (R&D) demonstrations, non-INEL R&D demonstrations, and office research and technical review meetings. Each project will have a test plan detailing the specific procedures, objectives, and tasks of the test. Therefore, information that is specific to testing each technology is intentionally limited in this document.

This report gives the second year`s findings of a study of how thermal and radiological processes may change the composition of organic compounds in the underground tanks at Hanford. Efforts were focused on the global reaction kinetics in a simulated waste exposed to {gamma} rays and the reactions of organic radicals with nitrite ion. The gas production is predominantly radiolytic. Decarboxylation of carboxylates is probably an aging pathway. TBP was totaly consumed in almost every run. Radiation clearly accelerated consumption of the other compounds. EDTA is more reactive than citrate. Oximes and possibly organic nitro compounds are key intermediates in the radiolytic redox reactions of organic compounds with nitrate/nitrite. Observations are consistent with organic compounds being progressively degraded to compounds with greater numbers of C-O bonds and fewer C-H and C-C bonds, resulting in an overall lower energy content. If the radwaste tanks are adequately ventilated and continually dosed by radioactivity, their total energy content should have declined. Level of risk depends on how rapidly carboxylate salts of moderate energy content (including EDTA fragments) degrade to low energy oxalate and formate.

The Department of Energy has consolidated its plans for Information Systems, Computing Resources, and Telecommunications into a single document, the Information Technology Resources Long-Range Plan. The consolidation was done as a joint effort by the Office of ADP Management and the Office of Computer Services and Telecommunications Management under the Deputy Assistant Secretary for Administration, Information, and Facilities Management. This Plan is the product of a long-range planning process used to project both future information technology requirements and the resources necessary to meet those requirements. It encompasses the plans of the various organizational components within the Department and its management and operating contractors over the next 5 fiscal years, 1991 through 1995.

This is the signed Financial Service fiscal year 1995 Site Support Program Plan, Work Breakdown Structure 6.10.4, for the Hanford site. This plan is intended to enable the contractor to accomplish the following: ensure financial integrity in all Westinghouse Hanford Company (WHC) operation while supporting the programmatic activities of WHC, the US Department of Energy, Richland Operations Office, and other Hanford contractors; provide efficient and effective financial services, and value added audits and review that enable management to enhance future operational results.

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The purpose of this revision is to update the Line Item Project, 93-L-GFW-152 Functional Design Criteria (FDC) to reflect changes approved in change control M-24-91-6, Engineering Change Notices (ECNs), and expand the scope to include subsurface investigations along with the borehole drilling. This revision improves the ability and effectiveness of maintaining RCRA and Operational groundwater compliance by combining borehole and well drilling with subsurface data gathering objectives. The total projected number of wells to be installed under this project has decreased from 200 and the scope has been broadened to include additional subsurface investigation activities that usually occur simultaneously with most traditional borehole drilling and monitoring well installations. This includes borehole hydrogeologic characterization activities, and vadose monitoring. These activities are required under RCRA 40 CFR 264 and 265 and WAC 173-303 for site characterization, groundwater and vadose assessment and well placement.

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The DOE Geothermal Research Program Update reports contain a fair amount of technical detail and management information at the individual project level. DJE 2005

During the past several years, a considerable amount of work has been carried out showing that microbially enhanced oil recovery (MEOR) is promising and the resulting biotechnology may be deliverable. At Brookhaven National Laboratory (BNL), systematic studies have been conducted which dealt with the effects of thermophilic and thermoadapted bacteria on the chemical and physical properties of selected types of crude oils at elevated temperatures and pressures. Current studies indicate that during the biotreatment several chemical and physical properties of crude oils are affected. The oils are (1) emulsified; (2) acidified; (3) there is a qualitative and quantitative change in light and heavy fractions of the crudes; (4) there are chemical changes in fractions containing sulfur compounds; (5) there is an apparent reduction in the concentration of trace metals; and (6) the qualitative and quantitative changes appear to be microbial species dependent; and (7) there is a distinction between biodegraded and biotreated oils. The downstream biotechnological crude oil processing research performed thus far is of laboratory scale and has focused on demonstrating the technical feasibility of downstream processing with different types of biocatalysts under a variety of processing conditions. Quantitative economic analysis is the topic of the present project which …

The report provides a synopsis of the FY94/95 Thermal Stabilization Campaign. The FY94 Thermal Stabilization Campaign ran from November 1, 1994 to June 13, 1995 and stabilized 236 items (22 kg) of reactive plutonium bearing material. A total of 49 cans of stabilized material was moved to the vaults for interim storage. While the initial downtime was high, with an Operating Efficiency (OE) of 27% over the first 3 months, the OE improved to 78% during the last 5 months for an overall DE of 58%. The campaign was completed 85 days ahead of schedule thus exceeding the ``Excellent``date for the Performance Base Incentive (PBI) for this campaign by 25 business days.

In FY95, EG and G Energy Measurements, Inc. (EG and G/EM) continued to support efforts to protect endangered species and cultural resources at the Naval Petroleum Reserves in California (NPRC). These efforts are conducted to ensure NPRC compliance with regulations regarding the protection of listed species and cultural resources on Federal properties. Population monitoring activities are conducted annually for San Joaquin kit foxes, giant kangaroo rats, blunt-nosed leopard lizards, and Hoover`s wooly-star. To mitigate impacts of oil field activities on listed species, 674 preactivity surveys covering approximately 211 hectares (521 acres) were conducted in FY95. EG and G/EM also assisted with mitigating effects from third-party projects, primarily by conducting biological and cultural resource consultations with regulatory agencies. EG and G/EM has conducted an applied habitat reclamation program at NPRC since 1985. In FY95, an evaluation of revegetation rates on reclaimed and non-reclaimed disturbed lands was completed, and the results will be used to direct future habitat reclamation efforts at NPRC. In FY95, reclamation success was monitored on 50 sites reclaimed in 1985. An investigation of factors influencing the distribution and abundance of kit foxes at NPRC was initiated in FY94. Factors being examined include habitat disturbance, topography, grazing, coyote abundance, …

The Technical Training Center provides initial and continuing technical training for NRC staff and contractors to satisfy training needs defined by formal NRC staff qualification and training programs. Technical training includes reactor technology programs and specialized technical programs. Reactor technology programs include a spectrum of courses, including classroom and simulator instruction, in each of the four Nuclear Steam Supply System vendor designs--General Electric (GE), Westinghouse, Combustion Engineering (CE), and Babcock and Wilcox (B and W). Specialized technical training includes courses in engineering support, probabilistic risk assessment, radiation protection, fuel cycle technology, safeguards, and regulatory skills. The report presents the activities of the Technical Training Center in FY95 in support of the NRC`s mission.

This is the Fiscal Year 1995 Annual Report for the Advanced Manufacturing Science and Technology (AMST) sector of Los Alamos Tactical Goal 6, Industrial Partnering. During this past fiscal year, the AMST project leader formed a committee whose members represented the divisions and program offices with a manufacturing interest to examine the Laboratory`s expertise and needs in manufacturing. From a list of about two hundred interest areas, the committee selected nineteen of the most pressing needs for weapon manufacturing. Based upon Los Alamos mission requirements and the needs of the weapon manufacturing (Advanced Design and Production Technologies (ADaPT)) program plan and the other tactical goals, the committee selected four of the nineteen areas for strategic planning and possible industrial partnering. The areas selected were Casting Technology, Constitutive Modeling, Non-Destructive Testing and Evaluation, and Polymer Aging and Lifetime Prediction. For each area, the AMST committee formed a team to write a roadmap and serve as a partnering technical consultant. To date, the roadmaps have been completed for each of the four areas. The Casting Technology and Polymer Aging teams are negotiating with specific potential partners now, at the close of the fiscal year. For each focus area we have created a …