Multiple contributors to neurocognitive impairment in individuals with sickle cell disease have been identified. Research indicates that a history of cerebrovascular accidents, such as silent infarcts and strokes are associated with greater cognitive decline among children with sickle cell disease. Additionally, disease effects such as hemoglobin and hematocrit levels significantly effect cognitive performance among this population and should be taken into consideration when examining neurocognitive impairment. Further, previous studies show a significant relationship between child behavior problems, family functioning, and cognitive performance in children with sickle cell, marking those as important targets for intervention among this population. While cognitive decline with increased age is not typically examined in healthy child populations, some research indicates the presence of age effects in those with SCD. A majority of the literature addresses cognitive impairment from a broad perspective, while a limited number of studies have begun to address effects among specific cognitive domains. Using archival data from the National Institutes of Health's Cooperative Study of Sickle Cell Disease, results revealed that disease severity was negatively correlated with some aspects of cognitive functioning, including visual-spatial domains. Additionally, some measures of cognitive performance were inversely correlated with age. Consistent with hypothesized outcomes, family functioning was …

Autism spectrum disorder (ASD) presents with difficulties in social communication, repetitive and/or restricted behaviors, as well as variable language development. Individuals with suspected ASD ideally participate in assessments which include measures of cognitive abilities, adaptive functioning, language functioning, and ASD specific measures (i.e., ADOS, ADI-R). Diagnosis of ASD can occur confidently at 2 years of age, however, the mean age at diagnosis is 4-5 years old. Delays in diagnosis are accounted for by lacking professionals and centers with the capabilities to assess ASD, as well as long waitlists for assessments. Early identification and intervention have been shown to provide the best improvements in ASD symptomology. The aim of the current study was to conduct a program evaluation of an autism treatment center that was designed to provide high quality evidence-based interventions. The study determined if treatment-as-usual in that center yields the expected gains in adaptive functioning and corresponding decreases in barriers to learning. Results indicated improvement in scores on standardized direct assessment of milestone achievement and barriers to learning, but no significant improvement in adaptive skills via secondary informant questionnaire measures following 6 months of treatment. The overall sample size was small due to COVID-19 complications, lack of institutional procedures, …