Degree Department

Phylogenetic analysis of the CDGSH iron-sulfur binding domain reveals its ancient origin (open access)

Phylogenetic analysis of the CDGSH iron-sulfur binding domain reveals its ancient origin

This article reports on the origin, evolution, and diversification of the iron-sulfur (2Fe-2S) binding motif CDGSH.
Date: November 28, 2017
Creator: Sengupta, Soham; Nechushtai, Rachel; Jennings, Patricia A.; Onuchic, José N.; Padilla, Pamela A.; Azad, Rajeev K. et al.
System: The UNT Digital Library
The membrane pacemaker hypothesis: novel tests during the ontogeny of endothermy (open access)

The membrane pacemaker hypothesis: novel tests during the ontogeny of endothermy

Article explores the ‘membrane pacemaker’ hypothesis which proposes a biochemical explanation for among-species variation in resting metabolism, based on the positive correlation between membrane docosahexaenoic acid (DHA) and metabolic rate. The authors tested this hypothesis using a novel model, altricial red-winged blackbird nestlings, predicting that the proportion of DHA in muscle and liver membranes should increase with the increasing metabolic rate of the nestling as it develops endothermy. In support of the membrane pacemaker hypothesis, DHA proportions increased in membranes from pectoralis muscle, muscle mitochondria and liver during post-hatch development. By contrast, elevated dietary DHA had no effect on resting metabolic rate, despite causing significant changes to membrane lipid composition.
Date: March 29, 2018
Creator: Price, Edwin R.; Sirsat, Tushar S.; Sirsat, Sarah K. G.; Curran, Thomas; Venables, Barney J. & Dzialowski, Edward M. (Edward Michael)
System: The UNT Digital Library
Specialized impulse conduction pathway in the alligator heart (open access)

Specialized impulse conduction pathway in the alligator heart

Article describes a study which examines the conduction system in crocodiles (Alligator mississippiensis), the only ectothermic vertebrates with a full ventricular septum.
Date: March 22, 2018
Creator: Jensen, Bjarke; Boukens, Bastiaan J; Crossley, Dane A., II; Conner, Justin; Mohan, Rajiv A.; van Duijvenboden, Karel et al.
System: The UNT Digital Library