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Bulky Lesion Bypass Requires Dpo4 Binding in Distinct Conformations
Article describes study where researchers used single-molecule florescence resonance energy transfer (smFRET) experiments, classical molecular dynamics simulations, and nucleotide incorporation assays to investigate the mechanism by which the model Y-family polymerase, Dpo4, bypasses a (+)-cis-Benzo[a]pyrene (B[a]P)-N 2-dG adduct in DNA.
Date:
December 12, 2017
Creator:
Liyanage, Pramodha S.; Walker, Alice R.; Brenlla, Alfonso; Cisneros, Gerardo Andrés; Romano, Louis J. & Rueda, David S.
Object Type:
Article
System:
The UNT Digital Library
Gold at what cost? Another megaproject threatens biodiversity in the Amazon
Article discusses concerns and controversy related to the gold mining ‘Volta Grande Project’ at the Xingu River in northern Brazil.
Date:
June 26, 2017
Creator:
Tófoli, Raffael M.; Dias, Rosa M.; Alves, Gustavo H. Zaia; Hoeinghaus, David J.; Gomes, Luiz C.; Baumgartner, Matheus T. et al.
Object Type:
Article
System:
The UNT Digital Library
Determination of molar refractions and Abraham descriptors for tris(acetylacetonato)chromium(iii), tris(acetylacetonato)iron(iii) and tris(acetylacetonato)cobalt(iii)
Article describes study in which researchers determined molar refractions of tris(acetylacetonato)chromium(III), tris(acetylacetonato)iron(III) and tris(acetylacetonato)cobalt(III).
Date:
October 23, 2017
Creator:
Abraham, M. H. (Michael H.); Acree, William E. (William Eugene); Fucaloro, Anthony F. & Zanella, Andrew W.
Object Type:
Article
System:
The UNT Digital Library
Molecular Dynamics Simulations of the [2Fe–2S] Cluster-Binding Domain of NEET Proteins Reveal Key Molecular Determinants That Induce Their Cluster Transfer/Release
Article examines NEET proteins and aberrant cluster release, which is implicated in a variety of human diseases, including cancer.
Date:
October 31, 2017
Creator:
Pesce, Luca; Calandrini, Vania; Marjault, Henri-Baptiste; Lipper, Colin H.; Rossetti, Gulia; Mittler, Ron et al.
Object Type:
Article
System:
The UNT Digital Library
Development and use of a switchgrass (Panicum virgatum L.) transformation pipeline by the BioEnergy Science Center to evaluate plants for reduced cell wall recalcitrance
Article examines the creation of a transformation pipeline (TP) to produce plants with decreased recalcitrance and a laboratory information management system (LIMS) for data compilation from these plants. While many genes accepted into the TP resulted in transgenic switchgrass without modified lignin or biomass content, a group of genes with potential to improve lignocellulosic biofuel yields was identified. Results from transgenic lines targeting xyloglucan and lignin structure provide examples of the types of information available on switchgrass lines produced within BioEnergy Science Center (BESC).
Date:
December 22, 2017
Creator:
Nelson, Richard S.; Stewart, C. Neal; Gou, Jiqing; Holladay, Susan; Gallego-Giraldo, Lina; Flanagan, Amy et al.
Object Type:
Article
System:
The UNT Digital Library
A novel benzimidazole derivative, MBIC inhibits tumor growth and promotes apoptosis via activation of ROS-dependent JNK signaling pathway in hepatocellular carcinoma
This study further explores a prior screening program carried out using MTT assay that identified a series of novel benzimidazole derivatives, among which Methyl 2-(5-fluoro-2-hydroxyphenyl)-1H-benzo[d]imidazole-5-carboxylate (MBIC) showed highest anticancer efficacy compared to that of chemotherapeutic agent, cisplatin. In this article, the authors find that MBIC inhibited cell viability in different hepatocellular carcinoma (HCC) cell lines without exerting significant cytotoxic effects on normal liver cells. The results of this study demonstrate that MBIC may inhibit cell proliferation via ROS-mediated activation of the JNK signaling cascade in HCC cells.
Date:
January 12, 2017
Creator:
Dai, Xiaoyun; Wang, Ling Zhi; Deivasigamni, Amudha; Looi, Chung Yeng; Karthikeyan, Chandrabose; Trivedi, Piyush et al.
Object Type:
Article
System:
The UNT Digital Library
Giant increase in cross-magnetic-field transport rate as an electron-positron plasma cools
The article focuses on a study of an electron-positron plasma in thermal equilibrium within a uniform magnetic field using a classical trajectory Monte Carlo simulation. The cross-magnetic-field single-particle diffusion coefficient is evaluated as a function of the magnetic field strength and plasma temperature. The transport rate is found to increase by many orders of magnitude as the plasma temperature is lowered, for a magnetic field strength of 1 T. The sharp dependence on temperature is due to electrons and positrons becoming temporarily correlated and drifting across the magnetic field before dissociating.
Date:
October 5, 2017
Creator:
Aguirre, F. F. & Ordonez, Carlos A.
Object Type:
Article
System:
The UNT Digital Library
Self-Reporting Molecularly Imprinted Polymer for Label-Free Selective Electrochemical Sensing of p-synephrine†
This article is taken from the Proceedings of the 5th International Symposium on Sensor Science (I3S 2017). Molecularly imprinted polymers (MIPs) can be used in applications in selective chemosensing.
Date:
December 4, 2017
Creator:
Lach, Patrycja; Cieplak, Maciej; Sharma, Piyush S.; Sosnowska, Marta; D'Souza, Francis & Kutner, Wlodzimierz
Object Type:
Article
System:
The UNT Digital Library
Semi-Covalent Imprinting for Selective Protein Sensing at a Femtomolar Concentration Level
This abstract introduces the development of an inventive new technique for protein imprinting.
Date:
December 4, 2017
Creator:
Dabrowski, Marcin; Cieplak, Maciej; Sharma, Piyush S.; Borowicz, Pawel; Noworyta, K.; Kuhn, Alexander et al.
Object Type:
Article
System:
The UNT Digital Library
Badly approximable points on self-affine sponges and the lower Assouad dimension
This article highlights a connection between Diophantine approximation and the lower Assouad dimension by using information about the latter to show that the Hausdorff dimension of the set of badly approximable points that lie in certain non-conformal fractals, known as self-affine sponges, is bounded below by the dynamical dimension of these fractals. The results, which are the first to advance beyond the conformal setting, encompass both the case of Sierpiński sponges/carpets (also known as Bedford–McMullen sponges/carpets) and the case of Barański carpets.
Date:
June 20, 2017
Creator:
Das, Tushar; Fishman, Lior; Simmons, David & Urbański, Mariusz
Object Type:
Article
System:
The UNT Digital Library
Computational design of environmental sensors for the potent opioid fentanyl
This article describes the computational design of proteins that bind the potent analgesic fentanyl.
Date:
September 19, 2017
Creator:
Bick, Matthew J.; Greisen, Per J.; Morey, Kevin J.; Antunes, Mauricio S.; La, David; Sankaran, Banumathi et al.
Object Type:
Article
System:
The UNT Digital Library
Concept Inventory Development Reveals Common Student Misconceptions about Microbiology
This article identifies misconceptions in microbiology held by undergraduate students upon entry into an introductory, general microbiology course.
Date:
October 30, 2017
Creator:
Briggs, Amy G.; Hughes, Lee E.; Brennan, R. E.; Buchner, John; Horak, Rachel E. A.; Katz-Amburn, D. Sue et al.
Object Type:
Article
System:
The UNT Digital Library
Development, Validation, and Application of the Microbiology Concept Inventory
This article describes the creation and validation of a new microbiology concept inventory using the American Society for Microbiology Curriculum Guidelines.
Date:
October 5, 2017
Creator:
Paustian, Timothy D.; Briggs, Amy G.; Brennan, R. E.; Boury, Nancy; Buchner, John; Harris, Shannon et al.
Object Type:
Article
System:
The UNT Digital Library
Charged Particle Reflection by a Planar Artificially Structured Boundary With Electrostatic Plugging
This article uses a classical trajectory Monte Carlo simulation to investigate an artificially structured boundary for confinement and control of charged particles.
Date:
November 30, 2017
Creator:
Hedlof, R. M. & Ordonez, Carlos A.
Object Type:
Article
System:
The UNT Digital Library
Editorial: Advances in Plant-Hemipteran Interactions
This editorial discusses sixteen manuscripts which address the physiology and molecular biology of plant-hemipteran interactions at different levels.
Date:
September 21, 2017
Creator:
Shah, Jyoti & Walling, Linda
Object Type:
Article
System:
The UNT Digital Library
Identification of bottlenecks in the accumulation of cyclic fatty acids in camelina seed oil
This article proposes a model for the accumulation of substantial levels of cyclopropane fatty acids (CPA) in camelina, and discusses the differences between CPA accumulation in camelina and Arabidopsis.
Date:
July 10, 2017
Creator:
Yu, Xiao-Hong; Cahoon, Rebecca E.; Horn, Patrick J.; Shi, Hai; Prakash, Richa R.; Cai, Yuanheng et al.
Object Type:
Article
System:
The UNT Digital Library
Xenopus and the art of oxygen maintenance
This column article discusses the impact of Robert Boutillier and Graham Shelton's 1986 Journal of Experimental Biology paper "Gas exchange, storage and transport in voluntarily diving Xenopus laevis."
Date:
November 15, 2017
Creator:
Tattersall, Glenn & Burggren, Warren W.
Object Type:
Article
System:
The UNT Digital Library
Black Hole Growth Is Mainly Linked to Host-galaxy Stellar Mass Rather Than Star Formation Rate
This article investigates the dependence of black hole accretion rate (BHAR) on host-galaxy star formation rate (SFR) and stellar mass in the CANDELS/GOODS-South field in the redshift range of 0.5 ⩽ z < 2.0.
Date:
June 15, 2017
Creator:
Yang, G.; Chen, C. -T. J.; Vito, F.; Brandt, William Nielsen; Alexander, David M.; Luo, Bin et al.
Object Type:
Article
System:
The UNT Digital Library
High-redshift AGN in the Chandra Deep Fields: the obscured fraction and space density of the sub-L∗ population
This article investigates the population of high-redshift (3≤z<6) active galactic nuclei (AGN) selected in the two deepest X-ray surveys, the 7 Ms Chandra Deep Field-South and 2 Ms Chandra Deep Field-North.
Date:
September 26, 2017
Creator:
Vito, F.; Brandt, William Nielsen; Yang, G.; Gilli, Roberto; Luo, Bin; Vignali, Christian et al.
Object Type:
Article
System:
The UNT Digital Library
Exploratory X-Ray Monitoring of Luminous Radio-quiet Quasars at High Redshift: No Evidence for Evolution in X-Ray Variability
This article reports on the second installment of an X-ray monitoring project of seven luminous radio-quiet quasars (RQQs).
Date:
October 10, 2017
Creator:
Shemmer, Ohad; Brandt, William Nielsen; Paolillo, Maurizio; Kaspi, Shai; Vignali, Christian; Lira, Paulina et al.
Object Type:
Article
System:
The UNT Digital Library
Tracing the accretion history of supermassive black holes through X-ray variability: results from the Chandra Deep Field-South
This article studies the X-ray variability properties of distant active galactic nuclei (AGNs) in the Chandra Deep Field-South region over 17 yr, up to z ~ 4, and compare them with those predicted by models based on local samples.
Date:
July 14, 2017
Creator:
Paolillo, Maurizio; Papadakis, I.; Brandt, William Nielsen; Luo, Bin; Xue, Yongquan; Tozzi, Paolo et al.
Object Type:
Article
System:
The UNT Digital Library
Deciphering pathogenicity and antibiotic resistance islands in methicillin-resistant Staphylococcus aureus genomes
This article explores the use of an information-entropy-based gene clustering method for genomic island detection in MRSA.
Date:
November 16, 2017
Creator:
Jani, Mehul; Sengupta, Soham; Hu, Kelsey & Azad, Rajeev K.
Object Type:
Article
System:
The UNT Digital Library
Existence of Solutions for Sublinear Equations on Exterior Domains
This article proves the existence of an infinite number of radial solutions of Δu+K(r)ƒ(u) = 0, one with exactly n zeros for each nonnegative integer n on the exterior of the ball of radius R > 0, Bʀ, centered at the origin in ℝᴺ with u = 0 on ∂Bʀ and limᵣ→∞u(r) = 0 where N > 2, f is odd with ƒ < 0 on (0; β), ƒ > 0 on (β;∞), ƒ(u) ~ uᵖ with 0 < p < 1 for large u and K(r) ~ r-α with 0 < α < 2 for large r.
Date:
October 10, 2017
Creator:
Iaia, Joseph A.
Object Type:
Article
System:
The UNT Digital Library
Existence and Nonexistence of Solutions for Sublinear Problems With Prescribed Number of Zeros on Exterior Domains
This article proves the existence of radial solutions of Δu + K(r)ƒ(u) = 0 on the exterior of the ball, of radius R, centered at the origin in ℝᴺ such that limᵣ→∞u(r) = 0 if R > 0 is sufficiently small.
Date:
May 16, 2017
Creator:
Joshi, Janak
Object Type:
Article
System:
The UNT Digital Library