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Chemical Conditioning as an Approach to Ischemic Stroke Tolerance: Mitochondria as the Target (open access)

Chemical Conditioning as an Approach to Ischemic Stroke Tolerance: Mitochondria as the Target

This article focuses on chemical conditioning of mitochondrial proteins as targets for neuroprotection against ischemic stroke injury.
Date: March 8, 2016
Creator: Jin, Zhen; Wu, Jinzi & Yan, Liang-Jun
System: The UNT Digital Library
Salvianolic Acid B (Sal B) Protects Retinal Pigment Epithelial Cells from Oxidative Stress-Induced Cell Death by Activating Glutaredoxin 1 (Grx1) (open access)

Salvianolic Acid B (Sal B) Protects Retinal Pigment Epithelial Cells from Oxidative Stress-Induced Cell Death by Activating Glutaredoxin 1 (Grx1)

The article explores Salvianolic acid B (Sal B), a natural compound, as a Grx1 inducer, which potently protected retinal pigment epithelial (RPE) cells from oxidative injury. Their results showed that treatment with Sal B protected primary human RPE cells from H₂O₂-induced cell damage. They found Sal B pretreatment upregulated Grx1 expression in RPE cells in a time- and dose-dependent manner.
Date: November 3, 2016
Creator: Liu, Xiaobin; Xavier, Christy; Jann, Jamieson & Wu, Hongli
System: The UNT Digital Library
Direct Analysis in Real Time (DART) of an Organothiophosphate at Ultrahigh Resolution by Fourier Transform Ion Cyclotron Resonance Mass Spectrometry and Tandem Mass Spectrometry (open access)

Direct Analysis in Real Time (DART) of an Organothiophosphate at Ultrahigh Resolution by Fourier Transform Ion Cyclotron Resonance Mass Spectrometry and Tandem Mass Spectrometry

Paper describes results of an analysis of the organothiophosphate malathion using DART-Fourier transform ion cyclotron resonance (FT-ICR) mass spectrometry (MS) and tandem mass spectrometry (MS/MS).
Date: January 16, 2016
Creator: Prókai, László, 1958- & Stevens, Stanley M.
System: The UNT Digital Library
Investigation of the Dermal Absorption and Irritation Potential of Sertaconazole Nitrate Anhydrous Gel (open access)

Investigation of the Dermal Absorption and Irritation Potential of Sertaconazole Nitrate Anhydrous Gel

Study used in vitro tape stripping to evaluate efficacy of an anhydrous gel containing sertaconazole nitrate.
Date: July 7, 2016
Creator: Manian, Mahima; Madrasi, Kumpal & Chaturvedula, Ayyappa
System: The UNT Digital Library
Nanoparticle Effects on Human Platelets in Vitro: A Comparison between PAMAM and Triazine Dendrimers (open access)

Nanoparticle Effects on Human Platelets in Vitro: A Comparison between PAMAM and Triazine Dendrimers

The article looks at Triazine and PAMAM dendrimers of similar size and number of cationic surface groups and compared them for their ability to promote platelet aggregation.
Date: March 29, 2016
Creator: Enciso, Alan E.; Neun, Barry; Rodriguez, Jamie & Ranjan, Amalendu P.
System: The UNT Digital Library
Safety of Continuous Infusion Ketorolac in Postoperative Coronary Artery Bypass Graft Surgery Patients (open access)

Safety of Continuous Infusion Ketorolac in Postoperative Coronary Artery Bypass Graft Surgery Patients

This article evaluates the safety of continuous infusion ketorolac which is sometimes utilized for analgesia in postoperative coronary artery bypass graft (CABG) patients. This retrospective cohort study evaluated the primary outcome of mortality and secondary outcomes of incidence of bleeding and myocardial infarction (MI). No association was found between continuous infusion ketorolac and increased risk of mortality, MI, or bleeding events in postoperative CABG patients.
Date: June 28, 2016
Creator: Howard, Meredith L.; Warhurst, Robert D. & Sheehan, Courtney
System: The UNT Digital Library