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Salvianolic Acid B (Sal B) Protects Retinal Pigment Epithelial Cells from Oxidative Stress-Induced Cell Death by Activating Glutaredoxin 1 (Grx1)
The article explores Salvianolic acid B (Sal B), a natural compound, as a Grx1 inducer, which potently protected retinal pigment epithelial (RPE) cells from oxidative injury. Their results showed that treatment with Sal B protected primary human RPE cells from H₂O₂-induced cell damage. They found Sal B pretreatment upregulated Grx1 expression in RPE cells in a time- and dose-dependent manner.
Date:
November 3, 2016
Creator:
Liu, Xiaobin; Xavier, Christy; Jann, Jamieson & Wu, Hongli
System:
The UNT Digital Library
Chemical Conditioning as an Approach to Ischemic Stroke Tolerance: Mitochondria as the Target
This article focuses on chemical conditioning of mitochondrial proteins as targets for neuroprotection against ischemic stroke injury.
Date:
March 8, 2016
Creator:
Jin, Zhen; Wu, Jinzi & Yan, Liang-Jun
System:
The UNT Digital Library