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Chemical Conditioning as an Approach to Ischemic Stroke Tolerance: Mitochondria as the Target (open access)

Chemical Conditioning as an Approach to Ischemic Stroke Tolerance: Mitochondria as the Target

This article focuses on chemical conditioning of mitochondrial proteins as targets for neuroprotection against ischemic stroke injury.
Date: March 8, 2016
Creator: Jin, Zhen; Wu, Jinzi & Yan, Liang-Jun
System: The UNT Digital Library
Salvianolic Acid B (Sal B) Protects Retinal Pigment Epithelial Cells from Oxidative Stress-Induced Cell Death by Activating Glutaredoxin 1 (Grx1) (open access)

Salvianolic Acid B (Sal B) Protects Retinal Pigment Epithelial Cells from Oxidative Stress-Induced Cell Death by Activating Glutaredoxin 1 (Grx1)

The article explores Salvianolic acid B (Sal B), a natural compound, as a Grx1 inducer, which potently protected retinal pigment epithelial (RPE) cells from oxidative injury. Their results showed that treatment with Sal B protected primary human RPE cells from H₂O₂-induced cell damage. They found Sal B pretreatment upregulated Grx1 expression in RPE cells in a time- and dose-dependent manner.
Date: November 3, 2016
Creator: Liu, Xiaobin; Xavier, Christy; Jann, Jamieson & Wu, Hongli
System: The UNT Digital Library