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A determination of the spatial concordance between Lyme disease incidence and habitat probability of its primary vector Ixodes scapularis (black-legged tick) (open access)

A determination of the spatial concordance between Lyme disease incidence and habitat probability of its primary vector Ixodes scapularis (black-legged tick)

This article involves mapping the probability of occurrence that the disease vector exists in the environment, mapping the incidence of Lyme disease in the human population and examining the spatial concordance between the probability map and incidence map.
Date: November 1, 2014
Creator: Atkinson, Samuel F.; Sarkar, Sahotra; Avina, Aldo; Schuermann, Jim A. & Williamson, Phillip C.
Object Type: Article
System: The UNT Digital Library
Synthesis, biological evaluation and in silico and in vitro mode-of-action analysis of novel dihydropyrimidones targeting PPAR-γ (open access)

Synthesis, biological evaluation and in silico and in vitro mode-of-action analysis of novel dihydropyrimidones targeting PPAR-γ

This article reports the synthesis and related biological activity of novel dihydropyrimidones.
Date: August 15, 2014
Creator: Bharathkumar, Hanumantharayappa; Paricharak, Shardul; Dinesh, K. R.; Siveen, Kodappully Sivaraman; Fuchs, Julian E.; Rangappa, Shobith et al.
Object Type: Article
System: The UNT Digital Library
Epigenetics as a Source of Variation in Comparative Animal Physiology - or - Lamarck Is Lookin' Pretty Good These Days (open access)

Epigenetics as a Source of Variation in Comparative Animal Physiology - or - Lamarck Is Lookin' Pretty Good These Days

This article discusses the ecological and and evolutionary significance of such epigenetic inheritance in a comparative physiological context, and provides a number of caveats and warnings regarding the interpretation of transgenerational phenotype modification as a true epigenetic phenomenon.
Date: February 26, 2014
Creator: Burggren, Warren W.
Object Type: Article
System: The UNT Digital Library
The Antimicrobial and Synergistic Efficiency of Antibiotic and Bacteriophage for the Treatment of Tuberculosis (open access)

The Antimicrobial and Synergistic Efficiency of Antibiotic and Bacteriophage for the Treatment of Tuberculosis

Paper describes a study exploring bacteriophages and antibiotics as a potential treatment for tuberculosis.
Date: 2014
Creator: Cai, Lucy
Object Type: Article
System: The UNT Digital Library
Ciclos de vida de insectos dulceacuícolas y cambio climático global en la ecorregión subantártica de Magallanes: investigaciones ecológicas a largo plazo en el Parque Etnobotánico Omora, Reserva de Biosfera Cabo de Hornos (55° S) (open access)

Ciclos de vida de insectos dulceacuícolas y cambio climático global en la ecorregión subantártica de Magallanes: investigaciones ecológicas a largo plazo en el Parque Etnobotánico Omora, Reserva de Biosfera Cabo de Hornos (55° S)

This article describes long-term studies the diversity, distribution and life histories of aquatic insects associated with the Róbalo River and other streams on Navarino Island.
Date: October 14, 2014
Creator: Contador, Tamara; Kennedy, James H.; Ojeda, Jaime; Feinsinger, Peter & Rozzi, Ricardo, 1960-
Object Type: Article
System: The UNT Digital Library
SPHK1 regulates proliferation and survival responses in triple-negative breast cancer (open access)

SPHK1 regulates proliferation and survival responses in triple-negative breast cancer

Article describes study suggesting that the inhibation of sphingosine kinase 1 (SPHK1) can attenuate ERK1/2 and AKT signaling and reduce growth of triple-negative breast cancer (TNBC) cells in vitro and in a xenograft SCID mouse model.
Date: March 27, 2014
Creator: Datta, Arpita; Loo, Ser Yue; Huang, Baohua; Wong, Lingkai; Tan, Sheryl S.L.; Tan, Tuan Zea et al.
Object Type: Article
System: The UNT Digital Library
Synthesis of Phenoxyacyl-Ethanolamides and Their Effects on Fatty Acid Amide Hydrolase Activity (open access)

Synthesis of Phenoxyacyl-Ethanolamides and Their Effects on Fatty Acid Amide Hydrolase Activity

This article discusses the synthesis of two sets of phenoxyacyl-ethanolamides from natural products, 3-n-pentadecylphenolethanolamide and cardanolethanolamide, with structural similarity to N-Acylethanolamines and characterizes their effects on the hydroltic activity of fatty acid amide hydrolase.
Date: February 20, 2014
Creator: Faure, Lionel; Nagarajan, Subbiah; Hwang, Hyeondo; Montgomery, Christa L.; Khan, Bibi Rafeiza; John, George et al.
Object Type: Article
System: The UNT Digital Library
Lignin Modification Leads to Increased Nodule Numbers in Alfalfa (open access)

Lignin Modification Leads to Increased Nodule Numbers in Alfalfa

Article on lignin modification leading to increased nodule numbers in alfalfa.
Date: March 2014
Creator: Gallego-Giraldo, Lina; Bhattarai, Kishor; Pislariu, Catalina I.; Nakashima, Jin; Jikumaru, Yusuke; Kamiya, Yūji et al.
Object Type: Article
System: The UNT Digital Library
A Broadly Implementable Research Course in Phage Discovery and Genomics for First-Year Undergraduate Students (open access)

A Broadly Implementable Research Course in Phage Discovery and Genomics for First-Year Undergraduate Students

Article discussing a broadly implementable research course in phage discovery and genomics for first-year undergraduate students.
Date: 2014
Creator: Jordan, Tuajuanda C.; Burnett, Sandra H.; Carson, Susan; Caruso, Steven M.; Clase, Kari L.; DeJong, Randall J. et al.
Object Type: Article
System: The UNT Digital Library
Florigen and anti-florigen – a systemic mechanism for coordinating growth and termination in flowering plants (open access)

Florigen and anti-florigen – a systemic mechanism for coordinating growth and termination in flowering plants

Article describes study establishing FLOWERING LOCUS T (FT) as a key flower-promoting gene in photoperiodic systems.
Date: September 16, 2014
Creator: Lifschitz, Eliezer; Ayre, Brian G. & Eshed, Yuval
Object Type: Article
System: The UNT Digital Library
MYB5 and MYB14 Play Pivotal Roles in Seed Coat Polymer Biosynthesis in Medicago truncatula (open access)

MYB5 and MYB14 Play Pivotal Roles in Seed Coat Polymer Biosynthesis in Medicago truncatula

Article discussing MYB5 and MYB14 playing pivotal roles in seed coat polymer biosynthesis in Medicago truncatula.
Date: August 2014
Creator: Liu, Chenggang; Jun, Ji Hyung & Dixon, R. A.
Object Type: Article
System: The UNT Digital Library
Environmental Awareness: A Survey of UNT Students’ Knowledge and Opinions (open access)

Environmental Awareness: A Survey of UNT Students’ Knowledge and Opinions

Paper discusses study examining awareness and opinions of environmental issues among students at the University of North Texas.
Date: 2014
Creator: McClinchie, Elizabeth
Object Type: Article
System: The UNT Digital Library
Factors affecting polyhydroxybutyrate accumulation in mesophyll cells of sugarcane and switchgrass (open access)

Factors affecting polyhydroxybutyrate accumulation in mesophyll cells of sugarcane and switchgrass

Article on factors affecting polyhydroxybutyrate accumulation in mesophyll cells of sugarcane and switchgrass.
Date: September 10, 2014
Creator: McQualter, Richard B.; Somleva, Maria N.; Gebbie, Leigh K.; Li, Xuemei; Petrasovits, Lars A.; Snell, Kristi D. et al.
Object Type: Article
System: The UNT Digital Library
Interplay between Bladder Microbiota and Urinary Antimicrobial Peptides: Mechanisms for Human Urinary Tract Infection Risk and Symptom Severity (open access)

Interplay between Bladder Microbiota and Urinary Antimicrobial Peptides: Mechanisms for Human Urinary Tract Infection Risk and Symptom Severity

This article explores the interrelationship between the urinary microbiota and host antimicrobial peptides as mechanisms for urinary tract infection risk.
Date: December 8, 2014
Creator: Nienhouse, Vanessa; Gao, Xiang; Dong, Qunfeng; Nelson, David E.; Toh, Evelyn; McKinley, Kathleen et al.
Object Type: Article
System: The UNT Digital Library
Botulinum Toxin Suppression of CNS Network Activity In Vitro (open access)

Botulinum Toxin Suppression of CNS Network Activity In Vitro

Article on botulinum toxin suppression of CNS network activity in vitro.
Date: February 12, 2014
Creator: Pancrazio, Joseph J.; Gopal, Kamakshi V.; Keefer, Edward W. & Gross, Guenter W.
Object Type: Article
System: The UNT Digital Library
Loss of Rare Fish Species from Tropical Floodplain Food Webs Affects Community Structure and Ecosystem Multifunctionality in a Mesocosm Experiment (open access)

Loss of Rare Fish Species from Tropical Floodplain Food Webs Affects Community Structure and Ecosystem Multifunctionality in a Mesocosm Experiment

Article on the loss of rare fish species from tropical floodplain food webs and how this affects community structure and ecosystem multifunctionality in a mesocosm experiment.
Date: February 3, 2012
Creator: Pendleton, Richard M.; Hoeinghaus, David; Gomes, Luiz C. & Agostinho, Angela A.
Object Type: Article
System: The UNT Digital Library
A deep transcriptomic analysis of pod development in the vanilla orchid (Vanilla planifolia) (open access)

A deep transcriptomic analysis of pod development in the vanilla orchid (Vanilla planifolia)

This research article describes very large gene sequence datasets from vanilla pods at different times of development, representing different tissue types, including the seeds, hairs, and placental and mesocarp tissues within the pod.
Date: November 7, 2014
Creator: Rao, Xiaolan; Krom, Nick; Tang, Yuhong; Widiez, Thomas; Havkin-Frenkel, Daphna; Belanger, Faith C. et al.
Object Type: Article
System: The UNT Digital Library
Generalization of Entropy Based Divergence Measures for Symbolic Sequence Analysis (open access)

Generalization of Entropy Based Divergence Measures for Symbolic Sequence Analysis

Article on the generalization of entropy based divergence measures for symbolic sequence analysis.
Date: September 17, 2013
Creator: Ré, Miguel A. & Azad, Rajeev K.
Object Type: Article
System: The UNT Digital Library

Comparison of Machine Learning Algorithms for Identifying Cancer Types

Poster for the 2014 MidSouth Computational Biology and Bioinformatics Society (MCBIOS) Annual Conference. This poster discusses a comparison of machine learning algorithms for identifying cancer types.
Date: March 2014
Creator: Saxena, Garima; Helsing, Joseph; Reyes, Omar Costilla & Azad, Rajeev K.
Object Type: Poster
System: The UNT Digital Library
Low neutral genetic diversity in isolated Greater Sage-Grouse (Centrocercus urophasianus) populations in northwest Wyoming (open access)

Low neutral genetic diversity in isolated Greater Sage-Grouse (Centrocercus urophasianus) populations in northwest Wyoming

This article contains an analysis of 16 microstatellite loci from 300 Greater Sage-Grouse individuals to assess genetic structure among populations in Wyoming and southeast Montana.
Date: March 26, 2014
Creator: Schulwitz, Sarah; Bedrosian, Bryan & Johnson, Jeff A.
Object Type: Article
System: The UNT Digital Library
Inhibition of STAT3 dimerization and acetylation by garcinol suppresses the growth of human hepatocellular carcinoma in vitro and in vivo (open access)

Inhibition of STAT3 dimerization and acetylation by garcinol suppresses the growth of human hepatocellular carcinoma in vitro and in vivo

Article on the inhibition of STAT3 dimerization and acetylation by garcinol suppresses the growth of human hepatocellular carcinoma in vitro and in vivo.
Date: March 21, 2014
Creator: Sethi, Gautam; Chatterjee, Snehajyoti; Rajendran, Peramaiyan; Li, Feng; Shanmugam, Muthu K.; Wong, Kwong Fai et al.
Object Type: Article
System: The UNT Digital Library
Oleanolic acid and its synthetic derivatives for the prevention and therapy of cancer: Preclinical and clinical evidence (open access)

Oleanolic acid and its synthetic derivatives for the prevention and therapy of cancer: Preclinical and clinical evidence

Article on oleanolic acid and its synthetic derivatives for the prevention and therapy of cancer with preclinical and clinical evidence.
Date: May 1, 2014
Creator: Shanmugam, Muthu K.; Dai, Xiaoyun; Kumar, Alan Prem; Tan, Benny K-H; Sethi, Gautam & Bishayee, Anupam
Object Type: Article
System: The UNT Digital Library
γ-tocotrienol inhibits angiogenesis-dependent growth of human hepatocellular carcinoma through abrogation of AKT/mammalian target of rapamycin pathway in an orthotopic mouse model (open access)

γ-tocotrienol inhibits angiogenesis-dependent growth of human hepatocellular carcinoma through abrogation of AKT/mammalian target of rapamycin pathway in an orthotopic mouse model

Article describing an investigation into whether γ-tocotrienol can abrogate angiogenesis-mediated tumor growth in hepatocellular carcinoma (HCC) and if so, through what molecular mechanisms.
Date: March 31, 2014
Creator: Siveen, Kodappully Sivaraman; Ahn, Kwang Seok; Ong, Tina H.; Shanmugam, Muthu K.; Li, Feng; Yap, Wei Ney et al.
Object Type: Article
System: The UNT Digital Library
Negative Regulation of Signal Transducer and Activator of Transcription-3 Signalling Cascade by Lupeol Inhibits Growth and Induces Apoptosis in Hepatocellular Carcinoma Cells (open access)

Negative Regulation of Signal Transducer and Activator of Transcription-3 Signalling Cascade by Lupeol Inhibits Growth and Induces Apoptosis in Hepatocellular Carcinoma Cells

In this article, the authors evaluate the effect of lupeol on STAT3 signalling cascade and its regulated functional responses in hepatocellular carcinoma (HCC) cells. Constitutive activation of signal transducer and activator of transcription signalling 3 (STAT3) has been linked with survival, proliferation and angiogenesis in a wide variety of malignancies including HCC. Lupeol exhibited its potential anticancer effects in HCC through the downregulation of STAT3-induced pro-survival signalling cascade.
Date: August 7, 2014
Creator: Siveen, Kodappully Sivaraman; Nguyen, An H.; Lee, J. H.; Li, Feng; Singh, S. S.; Kumar, Alan Prem et al.
Object Type: Article
System: The UNT Digital Library