This review summarizes the characteristics, evidences and development of CSCs, as well as implications and challenges for cancer treatment. Surgery, radiotherapy and chemotherapy are universally recognized as the most effective anti-cancer therapies. Recent studies have showed that cancer stem cells (CSCs), a small subpopulation of tumor cells, can generate bulk populations of nontumorigenic cancer cell progeny through the self-renewal and differentiation processes.

This presentation discusses the End of Term 2008 Presidential Web Archive. The University of North Texas (UNT) Libraries collaborated with members of the International Internet Preservation Consortium (IIPC) on the End of Term 2008 Presidential Web Harvest from October, 2008 to February, 2009. The project team archived 160,211,356 URIs during this collaboration, which became a research dataset for an IMLS-funded grant to investigate collection development using web archives. The project team analyzed the 10,318,073 PDFs and developed a retrieval and exploration system for collection developers interested in acquiring and developing born-digital collections from the End of Term Web Archive.

Photograph of sculptures on view as part of the Graduate Students' Sculpture Exhibition in the Lightwell Gallery in the Art Building on the University of North Texas Campus in December of 2012.

Photograph of sculptures on view as part of the Graduate Students' Sculpture Exhibition in the Lightwell Gallery in the Art Building on the University of North Texas campus in December of 2012.

Photograph of sculptures on view as part of the Graduate Students' Sculpture Exhibition in the Lightwell Gallery in the Art Building on the University of North Texas campus in December of 2012.

Photograph of sculptures on view as part of the Graduate Students' Sculpture Exhibition in the Lightwell Gallery in the Art Building on the University of North Texas campus in December of 2012.

Photograph of sculptures on view as part of the Graduate Students' Sculpture Exhibition in the Lightwell Gallery in the Art Building on the University of North Texas campus in December of 2012.

Photograph of sculptures on view as part of the Graduate Students' Sculpture Exhibition in the Lightwell Gallery in the Art Building on the University of North Texas campus in December of 2012.

Photograph of sculptures on view as part of the Graduate Students' Sculpture Exhibition in the Lightwell Gallery in the Art Building on the University of North Texas campus in December of 2012.