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The Impact of the 2002 Delaware Smoking Ordinance on Heart Attack and Asthma (open access)

The Impact of the 2002 Delaware Smoking Ordinance on Heart Attack and Asthma

This article analyzes the Delaware Hospital Discharge Database, and identified state and non-state residents discharged with AMI or asthma for the years 1999 to 2004. Statistical data analysis compared the incidence of AMI or asthma for each group before (1999–2002) and after (2003–2004) the amendment. As a result, the authors found that pre-ordinance and post-ordinance quarterly rates of AMI for Delaware residents were 451 (se = 21) and 430 (se = 21) respectively, representing a 4.7% reduction.
Date: December 2, 2010
Creator: Moraros, John; Bird, Yelena; Chen, Shande; Buckingham, Robert; Meltzer, Richard S.; Prapasiri, Surasri et al.
System: The UNT Digital Library
NSC109268 potentiates cisplatin-induced cell death in a p53-independent manner (open access)

NSC109268 potentiates cisplatin-induced cell death in a p53-independent manner

This article's study endeavors to determine if p53 is responsible for cisplatin sensitization by NSC109268. Results have implications for sensitivity of ovarian cancer cells to cisplatin independent of p53.
Date: October 5, 2010
Creator: Shankar, Eswar; Basu, Chandreyi; Adkins, Brett; Siede, Wolfram & Basu, Alakananda
System: The UNT Digital Library
Alcohol Withdrawal and Brain Injuries: Beyond Classical Mechanisms (open access)

Alcohol Withdrawal and Brain Injuries: Beyond Classical Mechanisms

This review attempts to provide integrated information at the levels of oxidative signaling mechanisms by which ethanol withdrawal (EW) provokes brain injuries and 17β-estradiol (E2) protects against it. Unmanaged sudden withdrawal from the excessive consumption of alcohol (ethanol) adversely alters neuronal integrity in vulnerable brain regions such as the cerebellum, hippocampus, or cortex.
Date: July 20, 2010
Creator: Jung, Marianna E. & Metzger, Daniel B.
System: The UNT Digital Library