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Genetic and Environmental Factors that Mediate Survival of Prolonged Oxygen Deprivation in the Nematode Caenorhabditis Elegans
Ischemic events of even a very short duration are not tolerated Ill in humans. The human cost of ischemia, when looked at as combined cardiovascular disease, dwarfs all other causes of death in the United States. Annually, CVD kills as many people in the US as does cancer, chronic lower respiratory disease, accidents, and diabetes mellitus combined. In 2005 (the latest year for which final statistics are available), CVD was responsible for 864,480 deaths or 35.3 percent of total deaths for the year. In my study, I have used the nematode Caenorhabditis elegans to determine genetic and environmental modulators of oxygen deprivation a key component of ischemia. I have found that animals with mutations in insulin like signaling pathways, neuronal function, electron transport chain components, germline function, and animals that are preconditioned by being raised on a diet of E. coli HT115 bacteria at 25°C have an enhanced ability to survive long-term (>72 hours) anoxia (<.005 kPa O2) at 20°C. The enhanced anoxia survival phenotype partially correlates with increased levels of carbohydrate stores in the nematodes. Suppression of this enhanced anoxia survival phenotype is possible by altering expression of the glycolytic enzyme glyceraldehyde-3-phosphate dehydrogenase, the FOXO transcription factor DAF-16, and …
Date:
August 2010
Creator:
LaRue, Bobby Lee, Jr.
System:
The UNT Digital Library
Electronic Sound Analysis with Hardware System and Remote Internet Display
Currently, standards from government agencies such as the National Institute for Occupation Safety and Health exist to aid in safeguarding individuals’ capacity for hearing, but only in factory settings in which large machines often produce loud levels of sound. Neglecting the fact that these preventative measures are only in place in the most limited of settings, no system currently exists to observe and report sound exposure levels in a manner timely or easily recognizable enough to adequately serve its purpose of hearing conservation. Musicians may also incur significant levels of risk for hearing loss in their day-to-day rehearsals and concerts, from high school marching bands to university wind bands. As a result, music school accrediting organizations such as the National Association of Schools of Music and even the European Union have begun taking steps meant to determine the risks associated with music. To meet these goals and improve upon current technologies, a system has been developed that electronically records sound levels utilizing modern hardware, increases the speed of reporting by transmitting data over computer networks and the Internet, and displays measures calculated from these data in a web browser for a highly viewable, user-friendly interface.
Date:
August 2010
Creator:
McCord, Cameron Forrest
System:
The UNT Digital Library
Chirped-Pulse Fourier Transform Microwave Spectroscopy of Fluoroiodoacetonitrile and Chloropentafluoroacetone
This work focuses on finding the complete iodine and nitrogen nuclear electric quadrupole coupling tensors for fluoroiodoacetonitrile using chirped-pulse Fourier transform microwave spectroscopy. Fluoroiodoacetonitrile contains two hyperfine nuclei, iodine (I=5/2) and nitrogen (I=1) and the spectra were observed with great resolution. A total of 499 transitions were observed for this molecule. The a, b and c rotational constants were obtained. A study of chloropentafluoroacetone was also done using chirped-pulse Fourier transform microwave spectroscopy. The two chlorine isotopes for this molecule, Cl-35 and Cl-37 were observed and 326 and 170 transitions were recorded, respectively.
Date:
December 2010
Creator:
Kadiwar, Gautam
System:
The UNT Digital Library
Homework versus daily quizzes: The effects on academic performance within high school pre-AP chemistry.
This research proposed to evaluate whether homework or daily quizzes were better for academic success within high-school pre-AP chemistry or if differences in the two methods were detectable. The study involved two years of data where homework was assigned and graded and one year of data where homework was suggested but daily quizzes provided the assessment. The mean of each of the unit tests were evaluated and t-tests were calculated. The results showed that over two-thirds of the units had statistically significant data when daily quizzes were utilized.
Date:
August 2010
Creator:
King, Jo Laurie Marushia
System:
The UNT Digital Library
"image"/ "i" / "nation": A Theory and Practice of Becoming an A/r/tographer
One can argue that embracing technological models may produce students who are illiterate in the "proper" methods of communication. With rapid technological change, some fear traditions in their "original" form may be lost. Practices such as trying to recapture the artist's intent should be abandoned as a way of opening up literacy discourse to multiple narratives. Failing to critically explore the possibilities of emerging models of thinking, teaching, and learning in a technological culture can produce a loss equal to the loss of tradition. An a/r/tographer works toward a fluid practice between the domains of artist, researcher, and teacher in order to negotiate emerging forms of visual/tactile/auditory communication which include the body as a networked organism situated recursively within the larger structure of society. This study occurred during two separate semesters of an art education course for pre-service elementary teachers. Through interaction with hypermedia, social networking, installation art, and mash-ups, the teacher and students became artists, researchers, and teachers in a community of practice. A new form of teaching practice was envisioned that opens the possibility for both collective and individual understandings in the formation of curricula. A set of guiding principles was invented through practice as a way of …
Date:
August 2010
Creator:
Sutherlin, Matthew Evans
System:
The UNT Digital Library
Surface Chemical Deposition of Advanced Electronic Materials
The focus of this work was to examine the direct plating of Cu on Ru diffusion barriers for use in interconnect technology and the substrate mediated growth of graphene on boron nitride for use in advanced electronic applications. The electrodeposition of Cu on Ru(0001) and polycrystalline substrates (with and without pretreatment in an iodine containing solution) has been studied by cyclic voltammetry (CV), current-time transient measurements (CTT), in situ electrochemical atomic force microscopy (EC-AFM), and X-ray photoelectron spectroscopy (XPS). The EC-AFM data show that at potentials near the OPD/UPD threshold, Cu crystallites exhibit pronounced growth anisotropy, with lateral dimensions greatly exceeding vertical dimensions. XPS measurements confirmed the presence and stability of adsorbed I on the Ru surface following pre-treatment in a KI/H2SO4 solution and following polarization to at least −200 mV vs. Ag/AgCl. CV data of samples pre-reduced in I-containing electrolyte exhibited a narrow Cu deposition peak in the overpotential region and a UPD peak. The kinetics of the electrodeposited Cu films was investigated by CTT measurements and applied to theoretical models of nucleation. The data indicated that a protective I adlayer may be deposited on an air-exposed Ru electrode as the oxide surface is electrochemically reduced, and that this …
Date:
December 2010
Creator:
Bjelkevig, Cameron
System:
The UNT Digital Library
Exploring Process-Variation Tolerant Design of Nanoscale Sense Amplifier Circuits
Sense amplifiers are important circuit components of a dynamic random access memory (DRAM), which forms the main memory of digital computers. The ability of the sense amplifier to detect and amplify voltage signals to correctly interpret data in DRAM cells cannot be understated. The sense amplifier plays a significant role in the overall speed of the DRAM. Sense amplifiers require matched transistors for optimal performance. Hence, the effects of mismatch through process variations must be minimized. This thesis presents a research which leads to optimal nanoscale CMOS sense amplifiers by incorporating the effects of process variation early in the design process. The effects of process variation on the performance of a standard voltage sense amplifier, which is used in conventional DRAMs, is studied. Parametric analysis is performed through circuit simulations to investigate which parameters have the most impact on the performance of the sense amplifier. The figures-of-merit (FoMs) used to characterize the circuit are the precharge time, power dissipation, sense delay and sense margin. Statistical analysis is also performed to study the impact of process variations on each FoM. By analyzing the results from the statistical study, a method is presented to select parameter values that minimize the effects of …
Date:
December 2010
Creator:
Okobiah, Oghenekarho
System:
The UNT Digital Library
Process-Voltage-Temperature Aware Nanoscale Circuit Optimization
Embedded systems which are targeted towards portable applications are required to have low power consumption because such portable devices are typically powered by batteries. During the memory accesses of such battery operated portable systems, including laptops, cell phones and other devices, a significant amount of power or energy is consumed which significantly affects the battery life. Therefore, efficient and leakage power saving cache designs are needed for longer operation of battery powered applications. Design engineers have limited control over many design parameters of the circuit and hence face many chal-lenges due to inherent process technology variations, particularly on static random access memory (SRAM) circuit design. As CMOS process technologies scale down deeper into the nanometer regime, the push for high performance and reliable systems becomes even more challenging. As a result, developing low-power designs while maintaining better performance of the circuit becomes a very difficult task. Furthermore, a major need for accurate analysis and optimization of various forms of total power dissipation and performance in nanoscale CMOS technologies, particularly in SRAMs, is another critical issue to be considered. This dissertation proposes power-leakage and static noise margin (SNM) analysis and methodologies to achieve optimized static random access memories (SRAMs). Alternate topologies …
Date:
December 2010
Creator:
Thakral, Garima
System:
The UNT Digital Library
Standing Up to Experts: The Politics of Public Education
In a small room in Austin, Texas, a group of 15 people are single-handedly deciding what is taught to the next generation of American children. The highly politicized 15 member Texas Board of Education is currently going through the once-in-a-decade process of rewriting the teaching and textbook standards for its nearly 5 million schoolchildren. Texas is also unbelievably influential on the standards that textbook publishers use as a basis for their textbooks nationwide. Over the last 10 years, the textbooks adopted by this board found their way in upwards of 65% of American classrooms. My goal is to shed light on this important issue and the key players in this process - I explain their goals, explore the scope of their influence, and delve into the personal motivations behind their actions, which will affect public education throughout the country.
Date:
December 2010
Creator:
Thurman, Scott
System:
The UNT Digital Library
Graph-Based Keyphrase Extraction Using Wikipedia
Keyphrases describe a document in a coherent and simple way, giving the prospective reader a way to quickly determine whether the document satisfies their information needs. The pervasion of huge amount of information on Web, with only a small amount of documents have keyphrases extracted, there is a definite need to discover automatic keyphrase extraction systems. Typically, a document written by human develops around one or more general concepts or sub-concepts. These concepts or sub-concepts should be structured and semantically related with each other, so that they can form the meaningful representation of a document. Considering the fact, the phrases or concepts in a document are related to each other, a new approach for keyphrase extraction is introduced that exploits the semantic relations in the document. For measuring the semantic relations between concepts or sub-concepts in the document, I present a comprehensive study aimed at using collaboratively constructed semantic resources like Wikipedia and its link structure. In particular, I introduce a graph-based keyphrase extraction system that exploits the semantic relations in the document and features such as term frequency. I evaluated the proposed system using novel measures and the results obtained compare favorably with previously published results on established benchmarks.
Date:
December 2010
Creator:
Dandala, Bharath
System:
The UNT Digital Library
A-Bu-GE: A Composition for Organ and Percussion
Keyphrases describe a document in a coherent and simple way, giving the prospective reader a way to quickly determine whether the document satisfies their information needs. The pervasion of huge amount of information on Web, with only a small amount of documents have keyphrases extracted, there is a definite need to discover automatic keyphrase extraction systems. Typically, a document written by human develops around one or more general concepts or sub-concepts. These concepts or sub-concepts should be structured and semantically related with each other, so that they can form the meaningful representation of a document. Considering the fact, the phrases or concepts in a document are related to each other, a new approach for keyphrase extraction is introduced that exploits the semantic relations in the document. For measuring the semantic relations between concepts or sub-concepts in the document, I present a comprehensive study aimed at using collaboratively constructed semantic resources like Wikipedia and its link structure. In particular, I introduce a graph-based keyphrase extraction system that exploits the semantic relations in the document and features such as term frequency. I evaluated the proposed system using novel measures and the results obtained compare favorably with previously published results on established benchmarks.
Date:
December 2010
Creator:
Kim, Chol-Ho
System:
The UNT Digital Library
Museum education: Creation, implementation, and evaluation of a web-based Elm Fork Natural Heritage Museum
Evaluation of museum audiences both in their physical and web-based spaces is a necessary component of museum education. For smaller museums without the personnel or knowledge to create a website and evaluate the on-line audience, using a web-based learning tool may be able to help these museums properly maintain an online site. A web-based Elm Fork Natural Heritage Museum (WBEFNHM) was created during the 2008 fall semester at the University of North Texas. The site included photographs and information from specimens housed within the physical Elm Fork Natural Heritage Museum. The site was available to three non-science majors' biology laboratory courses, and three science majors' biology laboratory courses during the 2009 spring and fall semesters. Student use of the WBEFNHM was tracked and found no significant difference between the amount of time science majors and non-majors spent on the site. This evaluation helps in understanding future use of an online EFNHM.
Date:
December 2010
Creator:
Lundeen, Melissa
System:
The UNT Digital Library
Examination and Development of the Correlation Consistent Composite Approach
The primary focus of this dissertation is the advancement of the correlation consistent composite approach (ccCA) methodology from its original formulation to the current implementation. Although for large main group test sets which contained both first- (Li-Ne) and second-row (Na-Ar) species ccCA produced chemical accuracy (generally estimated as a deviation of ~1 kcal mol-1 from reliable experiment), the second-row species were smaller in molecular size in comparison to their corresponding first-row species. Previous theoretical work has shown that the accuracy for theoretical calculations involving second-row species (specifically sulfur-containing species) are more basis set dependent than first-row species. Therefore, an analysis of the accuracy of ccCA for sulfur-containing species is warranted. The ccCA methodology is used to evaluate both enthalpies of formation and bond dissociation energies of sulfur-containing species as well as examine isomerization energies for three sets of sulfur-containing isomers. During the testing of ccCA for sulfur-containing species two observations were made which led to further investigations. First, there is no agreement between different theoretical methodologies on the lowest energetic isomer between SNO and NSO. In fact, G3 and G3B3 which differ only by the geometry of the single-point calculations do not agree on the lowest isomer. For this reason, …
Date:
December 2010
Creator:
Williams, T. Gavin
System:
The UNT Digital Library
Primary Compositional Characteristics in the Instrumental Music of Paul Lansky as Demonstrated in Hop (1993)
This dissertation provides insight into the compositional characteristics of Paul Lansky's instrumental works as demonstrated in Hop (1993). As well, this document intends to make Hop more approachable to performers through a structural, harmonic, and rhythmic analysis. This dissertation presents a brief overview of Lansky's biographical information, discusses background information about Marimolin (the ensemble that premiered the piece), and provides an analysis of Hop. Hop is analyzed with regard to form, harmony, and rhythm. The analysis was conducted through a tonal approach, and harmonies are identified with a lead sheet analysis. Personal interviews with Paul Lansky and marimbist Nancy Zeltsman provided significant insight into Lansky's influences, musical characteristics, as well as other elements pertaining to Hop.
Date:
December 2010
Creator:
Willie, Eric Jason
System:
The UNT Digital Library
The Function of Social Structure in Controlling Violent Crime in Turkey
This dissertation examines the relationship between social structural factors and violent crime rates in Turkey. The relationship between social structural characteristics and violent crime is worth exploring in areas that have attracted little academic attention, such as violent crime in Turkey. In order to understand and prevent the occurrence of crime, researchers have long investigated possible factors related to crime. Examining how crime varies across different regions can help us to understand underlying reasons for violent crime, which is considered one of the enduring problems in society. The findings of this research, to some extent, support the assumptions of social disorganization theory regarding the distribution of violent crime. Both the findings of multivariate and bivariate analysis indicated that poverty, unemployment, and family disruptions may have a positive effect on the distribution of violent crime in the cities of Turkey. The analysis of the effects of the social structure variables through the mediating variables, such as religious institutions, libraries and voluntary associations on the number of violent crimes and violent criminals, to some extent, support the tenets of social disorganization theory. However, all mediating variables cannot mediate all the indirect effects of social structural covariates. In brief, none of their indirect …
Date:
December 2010
Creator:
Guclu, Idris
System:
The UNT Digital Library
Singing the Republic: Polychoral Culture at San Marco in Venice (1550-1615)
During the late sixteenth and early seventeenth centuries, Venetian society and politics could be considered as a "polychoral culture." The imagination of the republic rested upon a shared set of social attitudes and beliefs. The political structure included several social groups that functioned as identifiable entities; republican ideologies construed them together as parts of a single harmonious whole. Venice furthermore employed notions of the republic to bolster political and religious independence, in particular from Rome. As is well known, music often contributes to the production and transmission of ideology, and polychoral music in Venice was no exception. Multi-choir music often accompanied religious and civic celebrations in the basilica of San Marco and elsewhere that emphasized the so-called "myth of Venice," the city's complex of religious beliefs and historical heritage. These myths were shared among Venetians and transformed through annual rituals into communal knowledge of the republic. Andrea and Giovanni Gabrieli and other Venetian composers wrote polychoral pieces that were structurally homologous with the imagination of the republic. Through its internal structures, polychoral music projected the local ideology of group harmony. Pieces used interaction among hierarchical choirs - their alternation in dialogue and repetition - as rhetorical means, first to create …
Date:
December 2010
Creator:
Yoshioka, Masataka
System:
The UNT Digital Library
Software and Hardware-In-The-Loop Modeling of an Audio Watermarking Algorithm
Due to the accelerated growth in digital music distribution, it becomes easy to modify, intercept, and distribute material illegally. To overcome the urgent need for copyright protection against piracy, several audio watermarking schemes have been proposed and implemented. These digital audio watermarking schemes have the purpose of embedding inaudible information within the host file to cover copyright and authentication issues. This thesis proposes an audio watermarking model using MATLAB® and Simulink® software for 1K and 2K fast Fourier transform (FFT) lengths. The watermark insertion process is performed in the frequency domain to guarantee the imperceptibility of the watermark to the human auditory system. Additionally, the proposed audio watermarking model was implemented in a Cyclone® II FPGA device from Altera® using the Altera® DSP Builder tool and MATLAB/Simulink® software. To evaluate the performance of the proposed audio watermarking scheme, effectiveness and fidelity performance tests were conducted for the proposed software and hardware-in-the-loop based audio watermarking model.
Date:
December 2010
Creator:
Zarate Orozco, Ismael
System:
The UNT Digital Library
Culture and Self-Representation in the Este Court: Ercole Strozzi's Funeral Elegy of Eleonora of Aragon, a Text, Translation, and Commentary.
This dissertation presents a previously unedited text by one of the most distinguished- yet neglected-Latin writers of the Italian Renaissance, Ercole Strozzi (1471-1508), a poet and administrator in the court of Ferrara. Under the Este Dukes, Ferrara became a major center of literary and artistic patronage. The Latin literary output of the court, however, has received insufficient scholarly scrutiny. The text is a verse funeral elegy of Eleonora of Aragon (1450-1493), the first Duchess of Ferrara. Eleonora was a remarkable woman whose talents and indefatigable efforts on behalf of her husband, her children, and her state, won her accolades both at home and abroad. She also served as a prototype for the remarkable careers of her two daughters, Isabella d'Este, and Beatrice d'Este, who are celebrated for their erudition and patronage of arts and letters. The text is a mirror of the Estense court and reveals to us how its members no doubt saw themselves, at the very peak of its temporal power and the height of its prestige as a center of cultural creativity. It is also important for the striking portrait it presents of Eleonora. Ercole Strozzi chose to call his poem an epicedium, an ancient minor literary …
Date:
December 2010
Creator:
Cassella, Dean Marcel
System:
The UNT Digital Library
Henderson Street Bazaar and Other Stories
The preface, "Against Buses: Charles Baxter and the Contemporary Epiphany" deals with the epiphany as a potential ending to short stories. Baxter holds that epiphanies are trite and without purpose in today's fiction. I argue that Baxter's view, while not without merit, is limiting. Beginning with James Joyce and Katherine Anne Porter and moving to my own work, I discuss how some epiphanies, particularly false ones, can enhance rather than detract from excellent fiction. Five short stories make up the remainder of this thesis: "Dedication," "Taking it with You," "Transition to Flowers," "Profile in Courage," and "Henderson Street Bazaar."
Date:
December 2010
Creator:
Briseño, J. Andrew
System:
The UNT Digital Library
The Key to Unlocking the Secret Window
David Koepp's Secret Window was released by Columbia Pictures in 2004. The film's score was written by Philip Glass and Geoff Zanelli. This thesis analyzes transcriptions from six scenes within the film in conjunction with movie stills from those scenes in an attempt to explain how the film score functions.
Date:
December 2010
Creator:
McConnell, Sarah E.
System:
The UNT Digital Library
Determinants of Mental Health Problems Among College Students
Many college students have reported struggling with mental health problems while dealing with challenging demands of college. The initial theoretical framework for this research was Pearlin's stress process model (SPM). Building on the SPM, the three additional mediating variables of perceived control, meaninglessness, and financial worries were added to create a composite model for the research. Mental health outcomes in the model were measured by a comprehensive range of factors, which included: psychological distress, suicide, substance abuse, and anger. Data were collected from a non-probability convenience sample of 463 undergraduate students attending a large state supported university in the southwestern region of the United States. Among the social status variables measured, being married, female, and white were significant predictors of poor mental health in the sampled college students. Poor self-image, feeling of meaninglessness, and worrying about current and future finances were significant mediating variables. Poor mental health could make individuals overwhelmed and discouraged. This is a formula for failure in college. The results of this study contribute to a better understanding of the correlates of mental health problems among college students. A greater understanding means that families and college administrations will have better ideas about how to intervene to reduce …
Date:
December 2010
Creator:
Mirbaha-Hashemi, Fariba
System:
The UNT Digital Library
Purification of Cyanide-Degrading Nitrilase from Pseudomonas Fluorescens NCIMB 11764.
Cyanide is a well known toxicant that arises in the environment from both biological and industrial sources. Bacteria have evolved novel coping mechanisms for cyanide and function as principal agents in the biosphere for cyanide recycling. Some bacteria exhibit the unusual ability of growing on cyanide as the sole nitrogen source. One such organism is Pseudomonas fluorescens NCIMB 11764 (Pf11764) which employs a novel oxidative mechanism for detoxifying and assimilating cyanide. A unique complex of enzymes referred to as cyanide oxygenase (CNO) is responsible for this ability converting cyanide to ammonia which is then assimilated. Because one component of the four member CNO complex was previously shown to act on cyanide independent of the other members, its characterization was sought as a means of gaining a better understanding of the overall catalytic mechanism of the complex. Preliminary studies suggested that the enzyme belonged to a subset of nitrilase enzymes known as cyanide dihydratases (CynD), however, a cynD-like gene in Pf11764 could not be detected by PCR. Instead, a separate nitrilase (Nit) linked to cyanide metabolism was detected. The corresponding nit gene was shown to be one of a conserved set of nit genes traced to a unique cluster in bacteria …
Date:
December 2010
Creator:
Chou, Chia-Ni
System:
The UNT Digital Library
Portrayal of Race by Public and Private University Newspapers
This study investigated how two college newspapers cover race and how the papers employed racial stereotypes when describing sources. One of newspapers is a student-produced paper at a private university. The other is a student-produced newspaper at a public university. The study conducted content analyses of front-page news stories in both college newspapers. The sources in the story were analyzed for racial stereotypes. Stereotypes were identified based on frames used in modern racism research. A t-test and chi-square were used to compare the coverage of minorities to Whites. Once the quantitative content analysis was completed, I used textual analysis to identify what ways the news stories used stereotypical coverage of minorities. The study used critical media theory.
Date:
December 2010
Creator:
Hayton, Tasha
System:
The UNT Digital Library
Endocannabinoid System in a Planarian Model
In this study, the presence and possible function of endocannabinoid ligands in the planarian is investigated. The endocannabinoids ananadamide (AEA) and 2-arachidonoylglycerol (2-AG) and entourage NAE compounds palmitoylethanolamide (PEA), stearoylethanolamide (SEA) and oleoylethanolamide (OEA) were found in Dugesia dorotocephala. Changes in SEA, PEA, and AEA levels were observed over the initial twelve hours of active regeneration. Exogenously applied AEA, 2-AG and their catabolic inhibition effected biphasic changes in locomotor velocity, analogous to those observed in murines. The genome of a close relative, Schmidtea mediterranea, courtesy of the University of Utah S. med genome database, was explored for cannabinoid receptors, none were found. A putative fatty acid amide hydrolase (FAAH) homolog was found in Schmidtea mediterranea.
Date:
December 2010
Creator:
Mustonen, Katie Lynn
System:
The UNT Digital Library