Prokaryotic life on earth is manifested by its diversity and omnipresence. These microbes serve as natural sources of a large variety of compounds with the potential to serve the ever growing, medicinal, chemical and transportation needs of the human population. However, commercially viable production of these compounds can be realized only through significant improvement of the native production capacity of natural isolates. The most favorable way to achieve this goal is through the genetic manipulation of metabolic pathways that direct the production of these molecules. While random mutagenesis and screening have dominated the industrial production of such compounds in the past our increased understanding of microbial physiology over the last five decades has shifted this trend towards rational approaches for metabolic design. Major drivers of this trend include recombinant DNA technology, high throughput characterization of macromolecular cellular components, quantitative modeling for metabolic engine ring, targeted combinatorial engineering and synthetic biology. In this chapter we track the evolution of microbial engineering technologies from the black box era of random mutagenesis to the science and engineering-driven era of metabolic design.

"Included in this publication is information about bluebirds and cavity nesting birds, the proper placement of nest boxes and simple plans for building wood nest boxes should you choose to do so in the future" (p. 1).

Transcript of an interview with Paul Anthony Sovik, U.S. Marine Corps (1st Marine Division) World War II veteran. Sovik discusses his family life and childhood in Ohio, decision to enlist with the Marine Corps following the bombing of Pearl Harbor, experiences with the 1st Marine Division in the Pacific Theater during World War II, and post-war life.

Training conducted as a part of the United Negro College Fund Special Programs/National Library of Medicine -HBCU ACCESS Project at Howard University, Washington, DC on November 20, 2010.

Training Manual updated for United Negro College Fund Special Programs Corporation/National Library of Medicine - HBCU ACCESS Project for Alcorn State University, Natchez, Mississippi, November 12, 2010

Environmental health focus with training conducted as part of the United Negro College Fund Special Programs Corporation/National Library of Medicine HBCU ACCESS Project at Winston-Salem State University, NC on November 10, 2010.

Training update with Environmental a health focus. Training conducted as part of the United Negro College Fund Special Programs Corporation/National Library of Medicine - HBCU ACCESS Project at the University of the District of Columbia, Washington, DC on November 2, 2010.

This document provides rules, regulations, and responsibilities of contractors that have been given approved Edwards Aquifer protection plans or Contributing Zone plans and approval letters. (p. 1).

Report submitted by the Texas Department of Transportation containing background information on the department, and summaries of requests for appropriations and expenditures for the fiscal years 2012 and 2013 with supporting documentation.

This document "focuses on the role of Health, Education, Access and Community in furthering engagement with nature and increasing understanding of Texas' natural resources. Stakeholder teams of content experts examined relevant issues, reviewed current research and developed recommendations for each focus area. The plan optimizes partnerships and relies on implementation across multiple public and private sectors. The full report includes their analyses of the problem, objectives and suggested action items" (p. 5).

John Thomas Biggers (1924–2001) was one of the most significant African American artists of the twentieth century. He was known for his murals, but also for his drawings, paintings, and lithographs, and was honored by a major traveling retrospective exhibition from 1995 to 1997. He created archetypal imagery that spoke positively to the rich and varied ethnic heritage of African Americans, long before the Civil Rights era drew attention to their African cultural roots. His influence upon other artists was profound, both for the power of his art and as professor and elder statesman to younger generations. Olive Jensen Theisen’s long-time commitment to the art of John Biggers resulted from the serendipitous discovery of an early Biggers mural in a school storeroom in the mid-1980s. Theisen immediately recognized the artist, the work, and its significance. She then set about returning The History of Negro Education in Morris County, Texas to a place of honor and found herself becoming a friend and recorder of John Biggers’s stories and experiences relating to the creation of his other murals too, including Family Unity at Texas Southern University. Containing more than eighty color and black-and-white illustrations, Walls That Speak is a richly illustrated update …

Biweekly, comprehensive compilation of decisions, reports, public notices, and other documents of the U.S. Federal Communications Commission.

Biweekly, comprehensive compilation of decisions, reports, public notices, and other documents of the U.S. Federal Communications Commission.