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Regulon inference without arbitrary thresholds: three levels of sensitivity
Reconstruction of transcriptional regulatory networks is one of the major challenges facing the bioinformatics community in view of constantly growing number of complete genomes. The comparative genomics approach has been successfully used for the analysis of the transcriptional regulation of many metabolic systems in various bacteria taxa. The key step in this approach is given a position weight matrix, find an optimal threshold for the search of potential binding sites in genomes. In our previous work we proposed an approach for automatic selection of TFBS score threshold coupled with inference of regulon content. In this study we developed two modifications of this approach providing two additional levels of sensitivity.
Date:
November 15, 2010
Creator:
Dubchak, Pavel Novichkov, Elena Stavrovskaya, Dmitry Rodionov, Andrey Mironov, Inna; Rodionov, Dmitry; Mironov, Andrey; Dubchak, Inna & Novichkov, P.S.
Object Type:
Poster
System:
The UNT Digital Library
"Robo-Signing" and Other Alleged Documentation Problems in Judicial and Nonjudicial Foreclosure Processes
Recent depositions involving major servicers, including GMAC Mortgage, J.P. Morgan Chase, and Wells Fargo, have raised concerns about "robo-signing" -- the practice of having a small number of individuals sign a large number of affidavits and other legal documents submitted to courts and other public authorities by mortgage companies to execute foreclosure. This report explores concerns related to these issues by explaining the mortgage market process, procedural problems that have surfaced during foreclosure proceedings, and other relevant information.
Date:
November 15, 2010
Creator:
Carpenter, David H.
Object Type:
Report
System:
The UNT Digital Library
Senior Recital: 2010-11-15 - Andy LaViolette, electric guitar and Melissa DeMarco, vocals
Access:
Use of this item is restricted to the UNT Community
Recital presented at the UNT Kenton Hall in partial fulfillment of the Bachelor of Music (BM) degree.
Date:
November 15, 2010
Creator:
LaViolette, Andy & DeMarco, Melissa
Object Type:
Sound
System:
The UNT Digital Library
[Student being helped by the teacher]
Photograph of students being helped by their teacher during an activity. She is attaching a stick to their fingers and wrist using tape. The students are waiting in a line to be helped. The teacher is a part of the Teach North Texas program.
Date:
November 15, 2010
Creator:
unknown
Object Type:
Photograph
System:
The UNT Digital Library
[Student doing task]
Photograph of a student working on an activity in their class. Their pointer and middle fingers are taped to a stick that is also taped to their wrist and they are trying to do a task with paperclips. He is wearing a Cowboys football jersey and a nametag that reads "Gates Gan". He is a part of the Teach North Texas program.
Date:
November 15, 2010
Creator:
unknown
Object Type:
Photograph
System:
The UNT Digital Library
[Student raising hand]
Photograph of a student that is part of the Teach North Texas program. They are seated on the ground by the classroom's backpack cubbies. Their hand is raised and on it they've taped a stick to their fingers and wrist.
Date:
November 15, 2010
Creator:
unknown
Object Type:
Photograph
System:
The UNT Digital Library
[Students doing activities]
Photograph of three students working on an activity in their class. Their pointer and middle fingers are taped to a stick that is also taped to their wrist and they are trying to do tasks with pennies and paperclips. The group is a part of the Teach North Texas UNT program.
Date:
November 15, 2010
Creator:
unknown
Object Type:
Photograph
System:
The UNT Digital Library
SUMMARY AND RESULTS LETTER REPORT – INDEPENDENT VERIFICATION OF THE HIGH FLUX BEAM REACTOR UNDERGROUND UTILITIES REMOVAL PROJECT, PHASE 3: TRENCHES 2, 3, AND 4 BROOKHAVEN NATIONAL LABORATORY UPTON, NEW YORK
5098-LR-02-0 SUMMARY AND RESULTS LETTER REPORT – INDEPENDENT VERIFICATION OF THE HIGH FLUX BEAM REACTOR UNDERGROUND UTILITIES REMOVAL PROJECT, PHASE 3 TRENCHES 2, 3, AND 4 BROOKHAVEN NATIONAL LABORATORY
Date:
November 15, 2010
Creator:
Harpenau, E. M.
Object Type:
Report
System:
The UNT Digital Library
Sweetwater Reporter (Sweetwater, Tex.), Vol. 113, No. 002, Ed. 1 Monday, November 15, 2010
Daily newspaper from Sweetwater, Texas that includes local, state, and national news along with advertising.
Date:
November 15, 2010
Creator:
unknown
Object Type:
Newspaper
System:
The Portal to Texas History
Taming the Plasma Material Interface with the Snowflake Divertor in NSTX
None
Date:
November 15, 2010
Creator:
Soukhanovskii, V. A.
Object Type:
Article
System:
The UNT Digital Library
Texas State of Office Risk Management Annual Financial Report: 2010
Annual financial report for the Texas State Office of Risk Management during fiscal year 2010 including balance sheets for revenues, expenditures, and various funds, with associated notes.
Date:
November 15, 2010
Creator:
Texas. State Office of Risk Management.
Object Type:
Report
System:
The Portal to Texas History
[TNT teacher with students]
Photograph of an unidentified teacher with the Teach North Texas program in her classroom with her students. She is doing something with the hand of one of the students while two others watch. Her walls are decorated with posters and information.
Date:
November 15, 2010
Creator:
unknown
Object Type:
Photograph
System:
The UNT Digital Library
The transcriptional diversity of 25 Drosophila cell lines
Drosophila melanogaster cell lines are important resources for cell biologists. Here, we catalog the expression of exons, genes, and unannotated transcriptional signals for 25 lines. Unannotated transcription is substantial (typically 19% of euchromatic signal). Conservatively, we identify 1405 novel transcribed regions; 684 of these appear to be new exons of neighboring, often distant, genes. Sixty-four percent of genes are expressed detectably in at least one line, but only 21% are detected in all lines. Each cell line expresses, on average, 5885 genes, including a common set of 3109. Expression levels vary over several orders of magnitude. Major signaling pathways are well represented: most differentiation pathways are ‘‘off’’ and survival/growth pathways ‘‘on.’’ Roughly 50% of the genes expressed by each line are not part of the common set, and these show considerable individuality. Thirty-one percent are expressed at a higher level in at least one cell line than in any single developmental stage, suggesting that each line is enriched for genes characteristic of small sets of cells. Most remarkable is that imaginal discderived lines can generally be assigned, on the basis of expression, to small territories within developing discs. These mappings reveal unexpected stability of even fine-grained spatial determination. No two …
Date:
November 15, 2010
Creator:
Cherbas, Lucy; Willingham, Aarron; Zhang, Dayu; Yang, Li; Zou, Yi; Eads, Brian D. et al.
Object Type:
Article
System:
The UNT Digital Library
Veterans Medical Care: FY2011 Appropriations
The Department of Veterans Affairs (VA) provides benefits to veterans through three major operating units, one of which is the Veterans Health Administration (VHA), on which this report focuses. This report will track the FY2011 appropriations process for funding VHA, and will be updated as legislative activities warrant.
Date:
November 15, 2010
Creator:
Panangala, Sidath Viranga
Object Type:
Report
System:
The UNT Digital Library
Walls That Speak: the Murals of John Thomas Biggers
Access:
Use of this item is restricted to the UNT Community
John Thomas Biggers (1924–2001) was one of the most significant African American artists of the twentieth century. He was known for his murals, but also for his drawings, paintings, and lithographs, and was honored by a major traveling retrospective exhibition from 1995 to 1997. He created archetypal imagery that spoke positively to the rich and varied ethnic heritage of African Americans, long before the Civil Rights era drew attention to their African cultural roots. His influence upon other artists was profound, both for the power of his art and as professor and elder statesman to younger generations. Olive Jensen Theisen’s long-time commitment to the art of John Biggers resulted from the serendipitous discovery of an early Biggers mural in a school storeroom in the mid-1980s. Theisen immediately recognized the artist, the work, and its significance. She then set about returning The History of Negro Education in Morris County, Texas to a place of honor and found herself becoming a friend and recorder of John Biggers’s stories and experiences relating to the creation of his other murals too, including Family Unity at Texas Southern University. Containing more than eighty color and black-and-white illustrations, Walls That Speak is a richly illustrated update …
Date:
November 15, 2010
Creator:
Theisen, Olive Jensen
Object Type:
Book
System:
The UNT Digital Library
Afghanistan and Iraq: DOD Should Improve Adherence to Its Guidance on Open Pit Burning and Solid Waste Management
A letter report issued by the Government Accountability Office with an abstract that begins "From the start of military operations in Afghanistan and Iraq, the U.S. military and its contractors have burned solid waste in open burn pits on or near military bases. According to the Department of Defense (DOD), burn pit emissions can potentially harm human health. U.S. Central Command (CENTCOM) guidance directs the military's use of burn pits, and the Department of Veterans' Affairs (VA) provides healthcare and other benefits to veterans and their families. GAO was asked to report on the (1) extent of open pit burning in Afghanistan and Iraq, and whether the military has followed its guidance; (2) alternatives to burn pits, and whether the military has examined them; and (3) extent of efforts to monitor air quality and potential health impacts. GAO visited four burn pits in Iraq, reviewed DOD data on burn pits, and consulted DOD and VA officials and other experts. GAO was unable to visit burn pits in Afghanistan."
Date:
October 15, 2010
Creator:
United States. Government Accountability Office.
Object Type:
Report
System:
The UNT Digital Library
The Altus Times (Altus, Okla.), Vol. 112, No. 224, Ed. 1 Friday, October 15, 2010
Daily newspaper from Altus, Oklahoma that includes local, state, and national news along with advertising.
Date:
October 15, 2010
Creator:
Bush, Michael
Object Type:
Newspaper
System:
The Gateway to Oklahoma History
Atmospheric Radiation Measurement Program Climate Research Facility Operations Quarterly Report July 1–September 30, 2010
Individual raw datastreams from instrumentation at the Atmospheric Radiation Measurement (ARM) Climate Research Facility fixed and mobile sites are collected and sent to the Data Management Facility (DMF) at Pacific Northwest National Laboratory (PNNL) for processing in near real-time. Raw and processed data are then sent approximately daily to the ARM Archive, where they are made available to users. For each instrument, we calculate the ratio of the actual number of data records received daily at the Archive to the expected number of data records. The results are tabulated by (1) individual datastream, site, and month for the current year and (2) site and fiscal year (FY) dating back to 1998.
Date:
October 15, 2010
Creator:
Sisterson, D. L.
Object Type:
Report
System:
The UNT Digital Library
The Baytown Sun (Baytown, Tex.), Vol. 90, No. 206, Ed. 1 Friday, October 15, 2010
Daily newspaper from Baytown, Texas that includes local, state, and national news along with advertising.
Date:
October 15, 2010
Creator:
Halter Gray, Janie
Object Type:
Newspaper
System:
The Portal to Texas History
Changes in the Arctic: Background and Issues for Congress
The diminishment of Arctic sea ice has led to increased human activities in the Arctic, and has heightened concerns about the region's future. Issues such as Arctic sovereignty claims; commercial shipping through the Arctic; Arctic oil, gas, and mineral exploration; endangered Arctic species; and increased military operations in the Arctic could cause the region in coming years to become an arena of international cooperation, competition, or conflict. This report provides an overview of Arctic-related issues for Congress, and refers readers to more in-depth CRS reports on specific Arctic-related issues.
Date:
October 15, 2010
Creator:
O'Rourke, Ronald
Object Type:
Report
System:
The UNT Digital Library
Comparison of the Current World Trade Center Medical Monitoring and Treatment Program and the World Trade Center Health Program Proposed by Title I of H.R. 847
This report compares the current federally supported medical screening and treatment program offered to various persons affected by the terrorist attack on New York City on September 11, 2001, with the federal program proposed to be established by Title I of H.R. 847, the James Zadroga 9/11 Health and Compensation Act of 2010, as amended and passed by the House of Representatives. The World Trade Center (WTC) Medical Monitoring and Treatment Program (MMTP) and the World Trade Center Health Program (WTCHP) are the specific programs compared in this report.
Date:
October 15, 2010
Creator:
Szymendera, Scott & Lister, Sarah A.
Object Type:
Report
System:
The UNT Digital Library
Cost-of-Living Adjustments for Federal Civil Service Annuities
Cost-of-living adjustments (COLAs) for the Civil Service Retirement System (CSRS) and the Federal Employees Retirement System (FERS) are based on the rate of inflation as measured by the Consumer Price Index for Urban Wage Earners and Clerical Workers (CPI-W). All CSRS retirees and survivors receive COLAs. Under FERS, however, non-disabled retirees under age 62 do not receive COLAs. This report discusses cost-of-living adjustments for government retirees, as well as related legislation.
Date:
October 15, 2010
Creator:
Isaacs, Katelin P.
Object Type:
Report
System:
The UNT Digital Library
Dallas Voice (Dallas, Tex.), Vol. 27, No. 22, Ed. 1 Friday, October 15, 2010
Weekly newspaper from Dallas, Texas that includes local, state, and national news and advertising of interest to the Lesbian, Gay, Bisexual, and Transgender (LGBT) community.
Date:
October 15, 2010
Creator:
Nash, Tammye
Object Type:
Newspaper
System:
The UNT Digital Library
The Deepwater Horizon Oil Spill: Coastal Wetland and Wildlife Impacts and Response
The explosion of the Deepwater Horizon drilling rig in the Gulf of Mexico on April 20, 2010, and the resulting oil spill began a cascade of effects on the coastal areas of the Gulf and on the wealth of species that inhabit those areas. This report addresses the importance of wetlands in general, the ecology of the coastal wetlands in the Gulf, impacts of oil spills on wetland habitats, response options, the implications of hurricane season for the spill's impacts, and cleanup and recovery issues. The emphasis is on the nearshore environment, although a few species found in deeper waters will be mentioned. In addition, some lessons from past spills such as the Exxon Valdez in Alaska will be discussed, along with issues that may arise as response and recovery transition to restoration of the Gulf.
Date:
October 15, 2010
Creator:
Corn, M. Lynne & Copeland, Claudia
Object Type:
Report
System:
The UNT Digital Library