Local thermal hot-spots in microprocessors lead to worst case provisioning of global cooling resources, especially in large-scale systems. However, efficiency of cooling solutions degrade non-linearly with supply temperature, resulting in high power consumption and cost in cooling - 50 {approx} 100% of IT power. Recent advances in active cooling techniques have shown on-chip thermoelectric coolers (TECs) to be very efficient at selectively eliminating small hot-spots, where applying current to a superlattice film deposited between silicon and the heat spreader results in a Peltier effect that spreads the heat and lowers the temperature of the hot-spot significantly to improve chip reliability. In this paper, we propose that hot-spot mitigation using thermoelectric coolers can be used as a power management mechanism to allow global coolers to be provisioned for a better worst case temperature leading to substantial savings in cooling power. In order to quantify the potential power savings from using TECs in data center servers, we present a detailed power model that integrates on-chip dynamic and leakage power sources, heat diffusion through the entire chip, TEC and global cooler efficiencies, and all their mutual interactions. Our multiscale analysis shows that, for a typical data center, TECs allow global coolers to operate …

Ultra intense short pulse laser pulses incident on solid targets can generate energetic protons. In additions to their potentially important applications such as in cancer treatments and proton fast ignition, these protons are essential to understand the complex physics of intense laser plasma interaction. To better characterize these laser-produced protons, we designed and constructed a novel, spatially imaging proton spectrometer that will not only measure proton energy distribution with high resolution, but also provide its angular characteristics. The information obtained from this spectrometer compliments those from commonly used diagnostics including radiochromic film packs, CR39 nuclear track detectors, and non-imaging magnetic spectrometers. The basic characterizations and sample data from this instrument are presented.

The CERN Axion Solar Telescope (CAST) is searching for solar axions which could be produced in the core of the Sun via the so-called Primakoff effect. Not only would these hypothetical particles solve the strong CP problem, but they are also one of the favored candidates for dark matter. In order to look for axions originating from the Sun, CAST uses a decommissioned LHC prototype magnet. In its 10 m long magnetic field region of 9 Tesla, axions could be reconverted into X-ray photons. Different X-ray detectors are installed on both ends of the magnet, which is mounted on a structure built to follow the Sun during sunrise and sunset for a total of about 3 hours per day. The analysis of the data acquired during the first phase of the experiment with vacuum in the magnetic field region yielded the most restrictive experimental upper limit on the axion-to-photon coupling constant for axion masses up to about 0.02 eV. In order to extend the sensitivity of the experiment to a wider mass range, the CAST experiment continues its search for axions with helium in the magnet bores. In this way it is possible to restore coherence of conversion for larger …

Cadmium Manganese Telluride (CdMnTe) recently emerged as a promising material for room-temperature X- and gamma-ray detectors. It offers several potential advantages over CdZnTe. Among them is its optimal tunable band gap ranging from 1.7-2.2 eV, and its relatively low (< 50%) content of Mn compared to that of Zn in CdZnTe that assures this favorable band-gap range. Another important asset is the segregation coefficient of Mn in CdTe that is approximately unity compared to 1.35 for Zn in CdZnTe, so ensuring the homogenous distribution of Mn throughout the ingot; hence, a large-volume stoichiometric yield is attained. However, some materials issues primarily related to the growth process impede the production of large, defect-free single crystals. The high bond-ionicity of CdMnTe entails a higher propensity to crystallize into a hexagonal structure rather than to adopt the expected zinc-blend structure, which is likely to generate twins in the crystals. In addition, bulk defects generate in the as-grown crystals due to the dearth of high-purity Mn, which yields a low-resistivity material. In this presentation, we report on our observations of such material defects in current CdMnTe materials, and our evaluation of its potential as an alternative detector material to the well-known CdZnTe detectors. We …

A general, efficient method is demonstrated for exchanging native oxyanionic ligands on inorganic nanocrystals with functional trimethylsilylated (TMS) chalcogenido ligands. In addition, newly synthesized TMS mixed chalcogenides leverage preferential reactivity of TMS-S bonds over TMS-O bonds, enabling efficient transfer of luminescent nanocrystals into aqueous media with retention of their optical properties.

Iron-sulfur (FeS) centers are essential for biology and inspirational in chemistry. These protein cofactors are broadly defined as active sites in which Fe is coordinated by S-donor ligands, often in combination with extra non-protein components, for example, additional metal atoms such as Mo and Ni, and soft ligands such as CN{sup -} and CO. Iron-sulfur centers are inherently air sensitive: they are found in essentially all organisms and it is possible that they were integral components of the earliest forms of life, well before oxygen (O{sub 2}) appeared. Proteins containing FeS cofactors perform a variety of biological functions ranging across electron transfer, acid-base catalysis, and sensing where they are agents for cell regulation through transcription (DNA) or translation (RNA). They are redox catalysts for radical-based reactions and the activation of H{sub 2}, N{sub 2} and CO{sub 2}, processes that offer scientific and economic challenges for industry. Iron-sulfur centers provide the focus for fundamental investigations of chemical bonding, spectroscopy and paramagnetism, and their functions have numerous implications for health and medicine and applications for technology, including renewable energy. The 2010 Iron-Sulfur Enzymes GRC will bring together researchers from different disciplines for in-depth discussions and presentations of the latest developments. There will …

We report extensive measurements of quantum oscillations in the normal state of the Fe-based superconductor LaFePO, (T{sub c} {approx} 6 K) using low temperature torque magnetometry and transport in high static magnetic fields (45 T). We find that the Fermi surface is in broad agreement with the band-structure calculations with the quasiparticle mass enhanced by a factor {approx}2. The quasi-two dimensional Fermi surface consist of nearly-nested electron and hole pockets, suggesting proximity to a spin/charge density wave instability.

Tissue that has undergone significant yet unknown amount of ischemic injury is frequently encountered in organ transplantation and trauma clinics. With no reliable real-time method of assessing the degree of injury incurred in tissue, surgeons generally rely on visual observation which is subjective. In this work, we investigate the use of optical spectroscopy methods as a potentially more reliable approach. Previous work by various groups was strongly suggestive that tissue autofluorescence from NADH obtained under UV excitation is sensitive to metabolic response changes. To test and expand upon this concept, we monitored autofluorescence and light scattering intensities of injured vs. uninjured rat kidneys via multimodal imaging under 355 nm, 325 nm, and 266 nm excitation as well as scattering under 500 nm illumination. 355 nm excitation was used to probe mainly NADH, a metabolite, while 266 nm excitation was used to probe mainly tryptophan to correct for non-metabolic signal artifacts. The ratio of autofluorescence intensities derived under these two excitation wavelengths was calculated and its temporal profile was fit to a relaxation model. Time constants were extracted, and longer time constants were associated with kidney dysfunction. Analysis of both the autofluorescence and light scattering images suggests that changes in microstructure …

The fiberboard assembly used in 9975 shipping packages as an impact-absorption and insulation component has the capacity to absorb moisture, with an accompanying change to its properties. While package fabrication requirements generally maintain the fiberboard moisture content within manufacturing range, there is the potential during use or storage for atypical handling or storage practices which result in the absorption of additional moisture. In addition to performing a transportation function, the 9975 shipping packages are used as a facility storage system for special nuclear materials at the Savannah River Site. A small number of packages after extended storage have been found to contain elevated moisture levels. Typically, this condition is accompanied by an axial compaction of the bottom fiberboard layers, and the growth of mold. In addition to potential atypical practices, fiberboard can exchange moisture with the surrounding air, depending on the ambient humidity. Laboratory data have been generated to correlate the equilibrium moisture content of cane fiberboard with the humidity of the surrounding air. These data are compared to measurements taken within shipping packages. With a reasonable measurement of the fiberboard moisture content, an estimate of the fiberboard properties can be made. Over time, elevated moisture levels will negatively impact …

We use magnetic force microscopy (MFM) to measure the local penetration depth {lambda} in Ba(Fe{sub 0.95}Co{sub 0.05}){sub 2}As{sub 2} single crystals and use scanning SQUID susceptometry to measure its temperature variation down to 0.4 K. We observe that superfluid density {rho}{sub s} over the full temperature range is well described by a clean two-band fully gapped model. We demonstrate that MFM can measure the important and hard-to-determine absolute value of {lambda}, as well as obtain its temperature dependence and spatial homogeneity. We find {rho}{sub s} to be uniform on the submicron scale despite the highly disordered vortex pinning.

The time-temperature-transformation (TTT) curve for the {delta} {yields} {alpha}{prime} isothermal martensitic transformation in a Pu-1.9 at. % Ga alloy is peculiar because it is reported to have a double-C curve. Recent work suggests that an ambient temperature conditioning treatment enables the lower-C curve. However, the mechanisms responsible for the double-C are still not fully understood. When the {delta} {yields} {alpha}{prime} transformation is induced by pressure, an intermediate {gamma}{prime} phase is observed in some alloys. It has been suggested that transformation at upper-C temperatures may proceed via this intermediate phase, while lower-C transformation progresses directly from {delta} to {alpha}{prime}. To investigate the possibility of thermally induced transformation via the intermediate {gamma}{prime} phase, in situ x-ray diffraction at the Advanced Photon Source was performed. Using transmission x-ray diffraction, the {delta} {yields} {alpha}{prime} transformation was observed in samples as thin at 30 {micro}m as a function of time and temperature. The intermediate {gamma}{prime} phase was not observed at -120 C (upper-C curve) or -155 C (lower-C curve). Results indicate that the bulk of the {alpha}{prime} phase forms relatively rapidly at -120 C and -155 C.

Several years ago, SRS completed a four year mission to decommission {approx}250 excess facilities. As part of that effort, SRS deactivated multiple facilities (e.g. Building 247-F, Naval Fuels Facility, and Building 211-F, Outside Facilities for F-Canyon) that contained extensive piping systems filled with hazardous material (e.g. nitric acid). Draining of hazardous materials from piping was successfully completed in all facilities without incident. In early 2009, the decommissioning program at SRS was restarted as a result of funding made available by the American Recovery & Reinvestment Act (ARRA). Under ARRA, draining of piping containing hazardous material was initiated in multiple facilities including Building 221-1F (or A-Line). This paper describes and reviews the draining of piping containing hazardous materials at A-Line, with emphasis on an incident involving the draining of nitric acid. The paper is intended to be a resource for engineers, planners, and project managers, who face similar draining challenges.

None

The Gordon Research Conference on Multiphoton Processes will be held for the 15th time in 2010. The meeting continues to evolve as it embraces both the rapid technological and intellectual growth in the field as well as the multi-disciplinary expertise of the participants. This time the sessions will focus on: (1) Ultrafast coherent control; (2) Free-electron laser experiments and theory; (3) Generation of harmonics and attosecond pulses; (4) Ultrafast imaging; (5) Applications of very high intensity laser fields; (6) Strong-field processes in molecules and solids; (7) Attosecond science; and (8) Controlling light. The scientific program will blur traditional disciplinary boundaries as the presenters and discussion leaders involve chemists, physicists, and optical engineers, representing both experiment and theory. The broad range of expertise and different perspectives of attendees should provide a stimulating and unique environment for solving problems and developing new ideas in this rapidly evolving field.

In 1999 an integrated biological control system was instituted at the U.S. Department of Energy's Hanford Site. Successes and changes to the program needed to be communicated to a large and diverse mix of organizations and individuals. Efforts at communication are directed toward the following: Hanford Contractors (Liquid or Tank Waste, Solid Waste, Environmental Restoration, Science and Technology, Site Infrastructure), General Hanford Employees, and Hanford Advisory Board (Native American Tribes, Environmental Groups, Local Citizens, Washington State and Oregon State regulatory agencies). Communication was done through direct interface meetings, individual communication, where appropriate, and broadly sharing program reports. The objectives of the communication efforts was to have the program well coordinated with Hanford contractors, and to have the program understood well enough that all stakeholders would have confidence in the work performed by the program to reduce or elimated spread of radioactive contamination by biotic vectors. Communication of successes and changes to an integrated biological control system instituted in 1999 at the Department of Energy's Hanford Site have required regular interfaces with not only a diverse group of Hanford contractors (i.e., those responsible for liquid or tank waste, solid wastes, environmental restoration, science and technology, and site infrastructure), and general Hanford …

We report results of low-temperature thermodynamic and transport measurements of Pb{sub 1-x}Tl{sub x}Te single crystals for Tl concentrations up to the solubility limit of approximately x = 1.5%. For all doped samples, we observe a low-temperature resistivity upturn that scales in magnitude with the Tl concentration. The temperature and field dependence of this upturn are consistent with a charge Kondo effect involving degenerate Tl valence states differing by two electrons, with a characteristic Kondo temperature T{sub K} {approx} 6 K. The observation of such an effect supports an electronic pairing mechanism for superconductivity in this material and may account for the anomalously high T{sub c} values.

The Nevada Test Site (NTS) began operating Material Control and Accountability (MC&A) under the Safeguards First Principle Initiative (SFPI), a risk-based and cost-effective program, in December 2006. The NTS SFPI Comprehensive Assessment of Safeguards Systems (COMPASS) Model is made up of specific elements (MC&A plan, graded safeguards, accounting systems, measurements, containment, surveillance, physical inventories, shipper/receiver differences, assessments/performance tests) and various sub-elements, which are each assigned effectiveness and contribution factors that when weighted and rated reflect the health of the MC&A program. The MC&A Cost Model, using an Excel workbook, calculates budget and/or actual costs using these same elements/sub-elements resulting in total costs and effectiveness costs per element/sub-element. These calculations allow management to identify how costs are distributed for each element/sub-element. The Cost Model, as part of the SFPI program review process, enables management to determine if spending is appropriate for each element/sub-element.

We consider scenarios with large flavour violating entries in the squark mass matrices focusing on the mixing between second and third generation squarks. These entries govern both, flavour violating low energy observables on the one hand and squark and gluino decays on the other hand. We first discuss the constraints on the parameter space due to the recent data on B mesons from the B factories and Tevatron. We then consider flavour violating squark and gluino decays and show that they can still be typically of order 10% despite the stringent constraints from low energy data. Finally we briefly comment on the impact for searches and parameter determinations at future collider experiments such as the upcoming LHC or a future International Linear Collider.

A {pi}-templated dynamic [2+2+1] clipping protocol is established for the synthesis of [2]catenanes from two parts dialdehyde, two parts diamine and one part tetracationic cyclophane. It is further diversified for the selective formation of an unsymmetrical [2]catenane showing great translational selectivity by employing two different dialdehydes in a one-pot reaction. The dual selectivity and the dynamic nature are verified by {sup 1}H NMR spectroscopy, X-ray single crystal structural studies and exchange experiments.

Replication Protein A (RPA) is the primary eukaryotic ssDNA binding protein utilized in diverse DNA transactions in the cell. RPA is a heterotrimeric protein with seven globular domains connected by flexible linkers, which enable substantial inter-domain motion that is essential to its function. Small angle X-ray scattering (SAXS) experiments on two multi-domain constructs from the N-terminus of the large subunit (RPA70) were used to examine the structural dynamics of these domains and their response to the binding of ssDNA. The SAXS data combined with molecular dynamics simulations reveal substantial interdomain flexibility for both RPA70AB (the tandem high affinity ssDNA binding domains A and B connected by a 10-residue linker) and RPA70NAB (RPA70AB extended by a 70-residue linker to the RPA70N protein interaction domain). Binding of ssDNA to RPA70NAB reduces the interdomain flexibility between the A and B domains, but has no effect on RPA70N. These studies provide the first direct measurements of changes in orientation of these three RPA domains upon binding ssDNA. The results support a model in which RPA70N remains structurally independent of RPA70AB in the DNA bound state and therefore freely available to serve as a protein recruitment module.

The Linac Coherent Light Source (LCLS) X-ray free electron laser project is currently under construction at the Stanford Linear Accelerator Center (SLAC). A new injector and upgrades to the existing accelerator were installed in two phases in 2006 and 2007. We report on the commissioning of the injector, the two new bunch compressors at 250MeV and 4.3 GeV, and transverse and longitudinal beam diagnostics up to the end of the existing linac at 13.6 GeV. The commissioning of the new transfer line from the end of the linac to the undulator is scheduled to start in November 2008 and for the undulator in March 2009 with first light to be expected in July 2009.

We discuss the cosmic ray spectra in annihilating/decaying Nambu-Goldstone dark matter models. The recent observed positron/electron excesses at PAMELA and Fermi experiments are well fitted by the dark matter with a mass of 3TeV for the annihilating model, while with a mass of 6TeV for the decaying model. We also show that the Nambu-Goldstone dark matter models predict a distinctive gamma-ray spectrum in a certain parameter space.

The muon and anti-muon neutrino energy spectrum is determined from 2000-2003 AMANDA telescope data using regularised unfolding. This is the first measurement of atmospheric neutrinos in the energy range 2-200 TeV. The result is compared to different atmospheric neutrino models and it is compatible with the atmospheric neutrinos from pion and kaon decays. No significant contribution from charm hadron decays or extraterrestrial neutrinos is detected. The capabilities to improve the measurement of the neutrino spectrum with the successor experiment IceCube are discussed.

The Department of Energy's Environmental Management (DOE-EM) Program is responsible for the receipt and storage of aluminum research reactor spent nuclear fuel or used fuel until ultimate disposition. Aluminum research reactor used fuel is currently being stored or is anticipated to be returned to the U.S. and stored at DOE-EM storage facilities at the Savannah River Site and the Idaho Nuclear Technology and Engineering Center. This paper assesses the technologies and the options for safe transportation/receipt and interim storage of aluminum research reactor spent fuel and reviews the comprehensive strategy for its management. The U.S. Department of Energy uses the Appendix A, Spent Nuclear Fuel Acceptance Criteria, to identify the physical, chemical, and isotopic characteristics of spent nuclear fuel to be returned to the United States under the Foreign Research Reactor Spent Nuclear Fuel Acceptance Program. The fuel is further evaluated for acceptance through assessments of the fuel at the foreign sites that include corrosion damage and handleability. Transport involves use of commercial shipping casks with defined leakage rates that can provide containment of the fuel, some of which are breached. Options for safe storage include wet storage and dry storage. Both options must fully address potential degradation of the …