Correspondence issued by the Government Accountability Office with an abstract that begins "The Los Alamos National Laboratory (LANL), which is operated by the National Nuclear Security Administration (NNSA), is responsible for, among other things, designing nuclear weapons. Over the past decade, we have documented numerous security, safety, and project management weaknesses at NNSA's nuclear weapons complex, including LANL. In particular, LANL has experienced a series of high-profile security incidents that have drawn attention to the laboratory's inability to account for and control classified information and maintain a safe work environment. In July 2004, LANL's director declared a suspension--or stand-down--of laboratory operations to address immediate concerns, including the loss of classified computer disks. During the stand-down, laboratory teams identified more than 3,400 security and safety issues. As a result of systemic management concerns, and the fact that the laboratory contractor--the University of California--did not adequately address these problems, the Department of Energy (DOE) decided in 2003 to allow other organizations to compete for the management contract at LANL. The University of California, which had been the exclusive management and operating contractor since the 1940s, was replaced in June 2006 by Los Alamos National Security, LLC, (LANS). LANS is a consortium of …

The objectives for this workshop were to bring together those with different viewpoints on the implementation of energy efficient ventilation in homes to share their perspectives. The primary benefit of the workshop is to allow the participants to get a broader understanding of the issues involved and thereby make themselves more able to achieve their own goals in this area. In order to achieve this objective each participant was asked to address four objectives from their point of view: (1) Drivers for energy efficient residential ventilation: Why is this an important issue? Who cares about it? Where is the demand: occupants, utilities, regulation, programs, etc? What does sustainability mean in this context? (2) Markets & Technologies: What products, services and systems are out there? What kinds of things are in the pipeline? What is being installed now? Are there regional or other trends? What are the technology interactions with other equipment and the envelope? (3) Barriers to Implementation: What is stopping decision makers from implementing energy-efficient residential ventilation systems? What kind of barriers are there: technological, cost, informational, structural, etc. What is the critical path? (4) Solutions: What can be done to overcome the barriers and how can/should we do …

The conclusions of this paper are: (1) The 5f electrons in Cm are near an LS coupling scheme. (2) This coupling scheme allows for a large spin polarization of the 5f electrons, which in turn stabilizes the Cm III crystal structure. (3) Results for Cm show us the recipe for magnetic stabilization of the crystal structure of metals: (A) The metal must be near the itinerant-localized transition where multiple crystal structures have close energies; (B) The metal is just on the magnetic side of the transition; and (C) There must be a magnetic moment large enough to overcome the energy difference between crystal structures, thus dictating the atomic geometry. (4) These results solidify our understanding of magnetically-stabilized metals, showing us where to look for engineered materials with magnetic applications.

A key challenge in tracking moving objects is the correspondence problem, that is, the correct propagation of object labels from one time step to another. This is especially true when the objects are non-rigid structures, changing shape, and merging and splitting over time. In this work, we describe a general approach to tracking thousands of non-rigid structures in an image sequence. We show how we can minimize memory requirements and generate accurate results while working with only two frames of the sequence at a time. We demonstrate our results using data from computer simulations of a fluimix problem.

Fragmentation is a fundamental process that naturally spans micro to macroscopic scales. Recent advances in algorithms, computer simulations, and hardware enable us to connect the continuum to microstructural regimes in a real simulation through a heterogeneous multiscale mathematical model. We apply this model to the problem of predicting how targets in the NIF chamber dismantle, so that optics and diagnostics can be protected from damage. The mechanics of the initial material fracture depend on the microscopic grain structure. In order to effectively simulate the fragmentation, this process must be modeled at the subgrain level with computationally expensive crystal plasticity models. However, there are not enough computational resources to model the entire NIF target at this microscopic scale. In order to accomplish these calculations, a hierarchical material model (HMM) is being developed. The HMM will allow fine-scale modeling of the initial fragmentation using computationally expensive crystal plasticity, while the elements at the mesoscale can use polycrystal models, and the macroscopic elements use analytical flow stress models. The HMM framework is built upon an adaptive mesh refinement (AMR) capability. We present progress in implementing the HMM in the NIF-ALE-AMR code. Additionally, we present test simulations relevant to NIF targets.

We have performed a quick analysis of the Mt. Meron seismic array to monitor regional seismic events in the Middle East. The Meron array is the only current array in the Levant and Arabian Peninsula and, as such, might be useful in contributing to event location, identification, and other analysis. Here, we provide a brief description of the array and a review of the travel time and array analysis done to assess its performance.

This cleanup verification package documents completion of remedial action for the 118-F-1 Burial Ground on the Hanford Site. This burial ground is a combination of two locations formerly called Minor Construction Burial Ground No. 2 and Solid Waste Burial Ground No. 2. This waste site received radioactive equipment and other miscellaneous waste from 105-F Reactor operations, including dummy elements and irradiated process tubing; gun barrel tips, steel sleeves, and metal chips removed from the reactor; filter boxes containing reactor graphite chips; and miscellaneous construction solid waste.

A robust redox extraction protocol for quantitative and reproducible metabolite isolation and recovery has been developed for simultaneous measurement of nicotinamide adenine dinucleotide (NAD) and its reduced form, NADH, from Saccharomyces cerevisiae. Following culture in liquid media, approximately 10{sup 8} yeast cells were harvested by centrifugation and then lysed under non-oxidizing conditions by bead blasting in ice-cold, nitrogen-saturated 50-mM ammonium acetate. To enable protein denaturation, ice cold nitrogen-saturated CH{sub 3}CN + 50-mM ammonium acetate (3:1; v:v) was added to the cell lysates. After sample centrifugation to pellet precipitated proteins, organic solvent removal was performed on supernatants by chloroform extraction. The remaining aqueous phase was dried and resuspended in 50-mM ammonium acetate. NAD and NADH were separated by HPLC and quantified using UV-VIS absorbance detection. Applicability of this procedure for quantifying NAD and NADH levels was evaluated by culturing yeast under normal (2% glucose) and calorie restricted (0.5% glucose) conditions. NAD and NADH contents are similar to previously reported levels in yeast obtained using enzymatic assays performed separately on acid (for NAD) and alkali (for NADH) extracts. Results demonstrate that it is possible to perform a single preparation to reliably and robustly quantitate both NAD and NADH contents in the same …

The Savannah River Site (SRS) is storing surplus plutonium (Pu) materials in the K-Area Materials Storage (KAMS) facility. The Pu materials are packaged per the DOE 3013 Standard. The nested, welded 300 series stainless steel 3013 containers are transported to KAMS in Type B shipping packages and subsequently stored in the same packages. These type B shipping packages consist of double containment vessels sealed with dual O-rings. The O-ring compound is Parker Seals V0835-75, based on Viton{reg_sign} GLT fluoroelastomer. This work evaluates the performance of the V0835-75 O-rings at accelerated-aging conditions. The results will be used to develop a lifetime prediction model for O-rings in KAMS.

Identifying the genomic regions bound by sequence-specific regulatory factors is central both to deciphering the complex DNA cis-regulatory code that controls transcription in metazoans and to determining the range of genes that shape animal morphogenesis. Here, we use whole-genome tiling arrays to map sequences bound in Drosophila melanogaster embryos by the six maternal and gap transcription factors that initiate anterior-posterior patterning. We find that these sequence-specific DNA binding proteins bind with quantitatively different specificities to highly overlapping sets of several thousand genomic regions in blastoderm embryos. Specific high- and moderate-affinity in vitro recognition sequences for each factor are enriched in bound regions. This enrichment, however, is not sufficient to explain the pattern of binding in vivo and varies in a context-dependent manner, demonstrating that higher-order rules must govern targeting of transcription factors. The more highly bound regions include all of the over forty well-characterized enhancers known to respond to these factors as well as several hundred putative new cis-regulatory modules clustered near developmental regulators and other genes with patterned expression at this stage of embryogenesis. The new targets include most of the microRNAs (miRNAs) transcribed in the blastoderm, as well as all major zygotically transcribed dorsal-ventral patterning genes, whose expression …

Free weekly newspaper that includes business and classified advertising.

Free weekly newspaper that includes business and classified advertising.

This report is intended to provide a summary of legislative attempts to address issues of energy development and preservation in the Refuge from the 95th Congress through the 110th Congress, with emphasis on the 107th through 110th Congresses.

This report examines key uncertainties in CO2 pipeline requirements for carbon capture and sequestration (CCS) by contrasting hypothetical pipeline scenarios in one region of the United States. The report summarizes the key factors influencing CO2 pipeline configuration for major power plants in the region, and illustrates how the viability of different sequestration sites may lead to enormous differences in pipeline costs.

Weekly Jewish newspaper from Fort Worth, Texas that includes local, state and national news along with extensive advertising.

Semi-weekly newspaper from Bastrop, Texas that includes local, state and national news along with advertising.

Weekly newspaper from Canadian, Texas that includes local, state and national news along with some advertising.

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This report explains the authorized generic pharmaceuticals effects on innovation.

This report mainly discusses about the Overview of Civil, Criminal, and Immigration Consequences on Immigration-Related Document Fraud. It also discusses about the primary civil, criminal , and immigration related penalties associated with immigration related document fraud.

A notice from the Texas Daily Newspaper Associations, which states that the deadline to enter the TDNA Awards is in five days, a January 15 deadline. The document requests that TDNA members pass the notice along to publishers, editors, copy editors, sportswriters, marketing and promotion staff who have worked hard to promote their newspapers to the community that the deadline is soon. The document also details the type of awards that are available. Winners will receive awards at the 2006 TDNA Annual Meeting on Monday, March 20, 2006 at the Renaissance Worthington Hotel in Fort Worth.

Free weekly newspaper that includes business and classified advertising.

Free weekly newspaper that includes business and classified advertising.

Free weekly newspaper that includes business and classified advertising.