A letter report issued by the General Accounting Office with an abstract that begins "Drug effectiveness and adverse events can vary between children and adults and among racial and ethnic groups. The Food and Drug Administration (FDA) is authorized under the pediatric exclusivity provision to grant drug sponsors 6 months of additional exclusive marketing rights for conducting clinical drug studies in children. The Best Pharmaceuticals for Children Act of 2002 (BPCA) expanded this provision to require FDA to take into account the adequacy of minority representation in pediatric exclusivity studies. BPCA also directed GAO to evaluate the representation of minorities in such studies. GAO examined the extent to which minority children are represented, whether drugs that treat diseases disproportionately affecting minority groups are studied under the provision, and FDA's monitoring of the representation of minority children in the studies. GAO reviewed related FDA documents, FDA requests for pediatric studies and final study results, and interviewed FDA officials and other experts."

A letter report issued by the General Accounting Office with an abstract that begins "The United Nations responded to the failure of some past peacekeeping operations by developing a strategy to help peacekeeping operations move a country from conflict to sustainable peace. It has attempted to apply this strategy to the large and costly peacekeeping operations in Sierra Leone, East Timor, and the Democratic Republic of the Congo since 2001. As a contributor of over 25 percent of the cost of U.N. operations, the United States has a stake in the successful application of this strategy. The strategy also has implications for the conduct of international peace operations in other post-conflict countries. GAO was asked to (1) identify the elements of the U.N. transition strategy; (2) assess the extent to which the United Nations has applied the strategy to operations; and (3) assess the challenges to implementing the strategy in these three countries."

A letter report issued by the General Accounting Office with an abstract that begins "In April 2003, Congress enacted the Postal Civil Service Retirement System (CSRS) Funding Reform Act of 2003 (P.L. 108-18), which\ lowered the Postal Service's (Service) annual payment for its CSRS obligation by over $2.5 billion beginning in fiscal year 2003. P.L. 108-18 includes requiring (1) the Service to begin making payments into an escrow account in fiscal year 2006, (2) the Service to issue a report on its proposed use of "savings" resulting from the lower CSRS payments, and (3) GAO to evaluate the Service's report and present its findings to Congress. GAO evaluated whether the Service's proposals were consistent with P.L. 108-18; the impact of the escrow account; and whether the proposals were fair to current and future ratepayers, affordable, and helped achieve transformation goals."

A letter report issued by the General Accounting Office with an abstract that begins "Pesticides play a significant role in increasing production of tobacco, food, and other crops by reducing the number of crop-destroying pests. However, if used improperly, pesticides can have significant adverse health effects. GAO was asked to (1) identify the pesticides commonly used on tobacco crops and the potential health risks associated with them, (2) determine how the Environmental Protection Agency (EPA) assesses and mitigates health risks associated with pesticides used on tobacco, and (3) assess the extent to which federal agencies regulate and test for pesticide residues on tobacco."

A letter report issued by the General Accounting Office with an abstract that begins "Small businesses, which are important to the U.S. economy for their roles in job creation and technological development, must be able to protect and profit from their innovations. One way to protect their innovations on a global basis is to obtain U.S. and foreign patents. These businesses, however, face numerous impediments when trying to patent their goods or processes abroad. These impediments, which GAO identified in a July 2002 report, include high costs, limited resources, and limited knowledge among small businesses about foreign patent laws and systems. Because of concern that small businesses, particularly high technology firms, were not obtaining patent protection abroad and thus were losing potential sales in foreign markets, GAO was asked to (1) identify the factors that patent law experts believe small businesses should consider as they decide whether to seek patent protection abroad and provide information on how small businesses viewed these factors and (2) identify the steps that small businesses should take to improve their foreign patent efforts, according to our survey of patent law experts."

A letter report issued by the General Accounting Office with an abstract that begins "The Postal Civil Service Retirement System Funding Reform Act of 2003 (the Act) required the United States Postal Service, Department of the Treasury, and Office of Personnel Management (OPM) to prepare proposals detailing whether and to what extent the Treasury and Postal Service should fund the benefits attributable to the military service of the Postal Service's current and former Civil Service Retirement System (CSRS) employees. The Act required GAO to evaluate the proposals. Our objective in doing so was to assess the agencies' positions and provide additional information where it may be useful."

A letter report issued by the General Accounting Office with an abstract that begins "Minority employees at the EPA reported for a number of years that the agency had discriminated against them based on their race and retaliated against them for filing complaints. These issues were aired at hearings held by the House Committee on Science at which EPA said it would take actions to ensure a fair and discrimination free workplace. GAO was asked to review (1) the accuracy of EPA's equal employment opportunity (EEO) data, (2) various issues about the processes used to resolve discrimination complaints, and (3) the disciplinary actions taken for managers who discriminate."

A letter report issued by the General Accounting Office with an abstract that begins "Money laundering is a serious crime, with hundreds of billions of dollars laundered annually. Congress passed the Money Laundering and Financial Crimes Strategy Act of 1998 to better coordinate the efforts of law enforcement agencies and financial regulators in combating money laundering. This act required the issuance of an annual National Money Laundering Strategy for 5 years, ending with the issuance of the 2003 strategy. To help with deliberations on reauthorization, GAO determined (1) agency perspectives on the benefit of the strategy and factors that affected its development and implementation, (2) whether the strategy has served as a useful mechanism for guiding the coordination of federal law enforcement agencies' efforts, (3) the role of the strategy in influencing the activities of federal financial regulators, and (4) whether the strategy has reflected key critical components."

This paper examines the relationship between system frequency, reliability and markets. It was prompted by the frequency deviations recently experienced at 2200 hours daily but is more generally concerned with the question of what frequency control is necessary. The paper does not provide new information or document new research. Nor is it intended to educate readers concerning power system engineering. Instead, the purpose is to reexamine well known truths concerning the power system and to freshly explore the basic relationship between frequency, reliability and markets: stepping back, if you will, to see if we are collectively missing something. The concern of this paper is with frequency and reliability. Off-nominal frequency can impact reliability and markets efficiency (as we are using the term here) in four ways. It could damage equipment (generation, transmission, or load). It could degrade the quality of the product being delivered to end users (too low and lights would flicker unacceptably, for example). It could result in the collapse of the power system itself (by triggering protective system actions, for example). Or it could result in overloading transmission lines as various generators try to restore system frequency impacting markets efficiency. Often these causes operate in concert. Generator …

The Global Fund to Fight AIDS, Tuberculosis, and Malaria, headquartered in Geneva, Switzerland, is a public-private partnership intended to attract and rapidly disburse new resources in developing countries for the struggle against infectious disease. Approximately $4.6 billion has been pledged to the Fund, while about $1.5 billion has been received or was in process as of June 13, 2004. A May 2003 report by the U.S. General Accounting Office (GAO) praised the Global Fund for "noteworthy progress in establishing essential governance and other supporting structures" but noted that the Fund's ability to finance additional grants was threatened by a lack of resources.

This report provides an overview of the various programs established by Titles III and V of the Higher Education Act (HEA). The report primarily focuses upon the structure of the programs, and includes data on participation and annual funding. It concludes with an analysis of possible issues related to Title III and Title V that may be considered during the HEA reauthorization.

This report provides an overview and some analysis of the patient safety legislation that is being considered by the 108th Congress. It begins with background information on the nature and causes of medical errors, followed by a brief comparison of the differences between mandatory and voluntary reporting systems. The report then discusses some of the legal and policy issues facing state mandatory reporting systems and major national voluntary reporting systems, and identifies design features of effective reporting programs. It concludes with a discussion and side-by-side comparison of H.R. 663 and S. 720.

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This report is intended for grant seekers in districts and states. This report has been expanded to include writing proposals for both government and private foundations grants. The report first discusses preliminary information gathering and preparation, developing ideas for the proposal, gathering community support, identifying funding resources, and seeking preliminary review of the proposal and support of relevant administrative officials.

This report outlines the floor procedure in the House of Representatives. The House considers bills and resolutions on the floor under several different sets of procedures governing the time for debate and the opportunities for amendment. Some procedures allow 40 or 60 minutes for debate; others permit debate to continue until a majority of Members vote to end it. Some procedures prohibit most or all floor amendments; others allow Members to offer any amendments that meet the requirements of the House's rules and precedents. Notwithstanding these differences, the rules, precedents, and practices of the House generally are designed to permit the majority to work its will in a timely manner.

Delayed coking evolved steadily over the early to mid 1900s to enable refiners to convert high boiling, residual petroleum fractions to light products such as gasoline. Pound for pound, coking is the most energy intensive of any operation in a modern refinery. Large amounts of energy are required to heat the thick, poor-quality petroleum residuum to the 900 to 950 degrees F required to crack the heavy hydrocarbon molecules into lighter, more valuable products. One common misconception of delayed coking is that the product coke is a disadvantage. Although coke is a low valued (near zero economic value) byproduct, compared to transportation fuels, there is a significant worldwide trade and demand for coke as it is an economical fuel. Coke production has increased steadily over the last ten years, with further increases forecast for the foreseeable future. Current domestic production is near 111,000 tons per day. A major driving force behind this increase is the steady decline in crude quality available to refiners. Crude slates are expected to grow heavier with higher sulfur contents while environmental restrictions are expected to significantly reduce the demand for high-sulfur residual fuel oil. Light sweet crudes will continue to be available and in even …

This report summarizes the work performed from 1 April 2003 to 30 September 2003 and recommends the tasks to be performed during Phase II (Pilot Evaluation). During this period discussions were held with various water agencies regarding use of the treated produced water either directly or indirectly through a water trading arrangement. In particular, several discussions were held with Monterey County Water Resources Agency, that has been charged with the long-term management and preservation of water resources in Monterey County. The Agency is very supportive of the program. However, they would like to see water quality/cost estimate data for the treated produced water from the pilot study prior to evaluating water use/water trade options. The agency sent a letter encouraging the project team to perform the pilot study to evaluate feasibility of the project. In addition, the regulations related to use of the treated water for various applications were updated during this period. Finally, the work plan, health and safety plan and sample analyses plan for performing pilot study to treat the oilfield produced water were developed during this period.

This report summarizes the results of the project entitled, ''Piecewise-Parabolic Methods for Parallel Computation with Applications to Unstable Fluid Flow in 2 and 3 Dimensions'' This project covers a span of many years, beginning in early 1987. It has provided over that considerable period the core funding to my research activities in scientific computation at the University of Minnesota. It has supported numerical algorithm development, application of those algorithms to fundamental fluid dynamics problems in order to demonstrate their effectiveness, and the development of scientific visualization software and systems to extract scientific understanding from those applications.

Can waste be transported safely to Yucca Mountain? Both the Department of Energy and the Nuclear Regulatory Commission have found that spent nuclear fuel can be shipped safely and securely. In fact, over the last 30 years there have been more than 2,700 shipments of spent nuclear fuel traveling more than 1.7 million miles, and there has never been a release of radioactive material harmful to the public or the environment--not one. Spent nuclear fuel is a solid material--it cannot leak, burn, or explode. The shipping containers, called casks, are the most robust in the transportation industry and must be certified by the Nuclear Regulatory Commission. They are designed to protect public health and safety under normal and severe accident conditions. Typically, every ton of shipped spent fuel is contained within approximately 4 tons of protective shielding and structural materials. How many shipments would be made to Yucca Mountain? DOE would use mainly trains and some legal-weight trucks to move spent nuclear fuel and high-level radioactive waste to Yucca Mountain. Once the repository opens, DOE estimates and average of 130 rail shipments and 45 truck shipments per year for 24 years.

The purpose of the Department of Energy's grant was to transfer to New Mexico and Utah a national award-winning market-based strategy to aggregate demand for wind energy. Their experiences over the past few years in New Mexico and utah have been quite different. In both states they have developed stronger relationships with utilities and policymakers which will increase the effectiveness of the future advocacy efforts.

This report reviews all potentially available Yucca Mountain Project (YMP) data in the Technical Data Management System and compiles all relevant qualified data, including data qualified by this report, on elastic properties, Poisson's ratio and Young's modulus, into a single summary Data Tracking Number (DTN) MO0304DQRIRPPR.002. Since DTN MO0304DQRIRPPR.002 was compiled from both qualified and unqualified sources, this report qualifies the DTN in accordance with AP-SIII.2Q. This report also summarizes the individual test results in MO0304DQRIRPPR.002 and provides summary values using descriptive statistics for Poisson's ratio and Young's modulus in a Reference Information Base Data Item. This report found that test conditions such as temperature, saturation, and sample size could influence test results. The largest influence, however, is the lithologic variation within the tuffs themselves. Even though the summary DTN divided the results by lithostratigrahic units within each formation, there was still substantial variation in elastic properties within individual units. This variation was attributed primarily to the presence or absence of lithophysae, fractures, alteration, pumice fragments, and other lithic clasts within the test specimens as well as changes in porosity within the units. As a secondary cause, substantial variations can also be attributed to test conditions such as the type …

The mission of this alliance is to promote, encourage, and facilitate computational science activities at the member HBCUs and to use collaborative technologies among the alliance partners to create an environment in which students and researchers from a wide variety of applications areas can exchange ideas and share resources.

This report describes batch laboratory experiments performed to determine the relative amounts of uranium incorporated in aluminosilicate structures during synthesis. The findings summarized here are based on laboratory experiments, which involved the synthesis of sodium aluminosilicates (NAS) structures, amorphous, zeolites A and sodalite phases in the presence of depleted uranium and the analytical search for incorporated uranium in NAS internal structures after synthesis. These studies will support the basis for continued operation of evaporators at the Savannah River Site (SRS).