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Base sequence effects on DNA replication influenced by bulky adducts. Final report, March 1, 1995--February 28, 1997
Polycyclic aromatic hydrocarbons (PAH) are environmental pollutants that are present in air, food, and water. While PAH compounds are chemically inert and are sparingly soluble in aqueous solutions, in living cells they are metabolized to a variety of oxygenated derivatives, including the high mutagenic and tumorigenic diol epoxide derivatives. The diol epoxides of the sterically hindered fjord region compound benzo[c]phenanthrene (B[c]PhDE) are among the most powerful tumorigenic compounds in animal model test systems. In this project, site-specifically modified oligonucleotides containing single B[c]PhDE-N{sup 6}-dA lesions derived from the reactions of the 1S,2R,3R,4S and 1R,2S,3S,4R diol epoxides of B[c]PhDE with dA residues were synthesized. The replication of DNA catalyzed by a prokaryotic DNA polymerase (the exonuclease-free Klenow fragment E. Coli Po1 I) in the vicinity of the lesion at base-specific sites on B[c]PhDE-modified template strands was investigated in detail. The Michaelis-Menten parameters for the insertion of single deoxynucleotide triphosphates into growing DNA (primer) strands using the modified dA* and the bases just before and after the dA* residue as templates, depend markedly on the stereochemistry of the B[c]PhDE-modified dA residues. These observations provide novel insights into the mechanisms by which bulky PAH-DNA adducts affect normal DNA replication.
Date:
May 31, 1997
Creator:
Geacintov, N. E.
Object Type:
Report
System:
The UNT Digital Library
The Chickasha Star (Chickasha, Okla.), Vol. 96, No. 37, Ed. 1 Saturday, May 31, 1997
Newspaper from Chickasha, Oklahoma that includes local, state, and national news along with advertising.
Date:
May 31, 1997
Creator:
Settle, David
Object Type:
Newspaper
System:
The Gateway to Oklahoma History
[Clipping: U.S. appeals court rules against Georgia lesbian]
Newspaper clipping from The Dallas Morning News about a workplace discrimination case in Georgia.
Date:
May 31, 1997
Creator:
The Dallas Morning News
Object Type:
Clipping
System:
The UNT Digital Library
Co-firing High Sulfur Coal with Refuse Derived Fuels. Technical Progress Report {number_sign}11
The objective of this quarter of study was to prepare fuel pellets containing PVC, newspaper and plastics to be co-fired with coal in the AFBC combustor. The Western Kentucky University atmospheric fluidized bed combustion system requires the fuel to fall from a bunker into a lock-hopper, and from there into a mixing box where the fuel is auger-fed under pressure into the bottom of the fluidized bed. The fuel must flow freely out of the bunker and through the lock- hopper for proper feeding into the combustor. In order for the fuel to continuously fall through these units and into the mixing box during combustion, the density of the fuel and the size of the particles must meet certain requirements. The particles must be no larger than 3/8 inches in diameter and must have a density approaching that of coal. Loose materials such as sawdust, shredded paper products and most shredded plastics do not feed properly in the WKU AFBC system. Bridging and blockage of feed chutes result, even with constant vibration of parts of the feed mechanism. It is not possible to run the AFBC system powered solely by these loose materials.
Date:
May 31, 1997
Creator:
Pan, Wei-Ping; Riley, John T. & Lloyd, William G.
Object Type:
Report
System:
The UNT Digital Library
Fuel efficient hydrodynamic containment for gas core fission reactor rocket propulsion. Final report, September 30, 1992--May 31, 1995
Gas core reactors can form the basis for advanced nuclear thermal propulsion (NTP) systems capable of providing specific impulse levels of more than 2,000 sec., but containment of the hot uranium plasma is a major problem. The initial phase of an experimental study of hydrodynamic confinement of the fuel cloud in a gas core fission reactor by means of an innovative application of a base injection stabilized recirculation bubble is presented. The development of the experimental facility, a simulated thrust chamber approximately 0.4 m in diameter and 1 m long, is described. The flow rate of propellant simulant (air) can be varied up to about 2 kg/sec and that of fuel simulant (air, air-sulfur hexafluoride) up to about 0.2 kg/sec. This scale leads to chamber Reynolds numbers on the same order of magnitude as those anticipated in a full-scale nuclear rocket engine. The experimental program introduced here is focused on determining the size, geometry, and stability of the recirculation region as a function of the bleed ratio, i.e. the ratio of the injected mass flux to the free stream mass flux. A concurrent CFD study is being carried out to aid in demonstrating that the proposed technique is practical.
Date:
May 31, 1997
Creator:
Sforza, P.M. & Cresci, R.J.
Object Type:
Report
System:
The UNT Digital Library
The Gilmer Mirror (Gilmer, Tex.), Vol. [120], No. [44], Ed. 1 Saturday, May 31, 1997
Semiweekly newspaper from Gilmer, Texas that includes local, state, and national news along with advertising.
Date:
May 31, 1997
Creator:
Overton, Mac
Object Type:
Newspaper
System:
The Portal to Texas History
Improved Efficiency of Miscible CO[sub]2 Floods and Enhanced Prospects for CO[sub]2 Flooding Heterogenous Reservoirs: Quarterly Technical Progress Report, January 1, 1997-March 31, 1997
Task 1: The technical paper, `Assessment of Foam Properties and Effectiveness in Mobility Reduction for C0{sub 2} Foam Floods,` was prepared and presented at the 1997 SPE International Symposium on Oilfield Chemistry. The paper covers five surfactants tested earlier for their foam properties. Work is progressing on evaluating surfactants and their foam properties under high pressure conditions by using a foam durability apparatus. Two surfactants, Witcolate 1259 and Witcolate 1276, were tested in this quarter and the new data were added into our existing database for correlation between foam properties in the bulk phase and in porous media. The new data support the earlier conclusion that foam stability and interfacial tension correlate with selective mobility reduction. Task 2: The changing permeability of the core during a series of foam tests is a significant factor in determining foam coreflood test parameters. A series of tests often requires hundreds of pore volumes of fluids to pass through the core. During this quarter, a new core was developed that should eliminate this problem and provide a constant base line. We ran a series of tests, which showed that this core has a constant permeability, as anticipated. We continued to examine procedures for history-matching …
Date:
May 31, 1997
Creator:
Grigg, R. B.; Schechter, D.S.; Chang, Shih-Hsien; Guo, Boyun; Tsau, Jyun-Syung & Casteel, J.F.
Object Type:
Report
System:
The UNT Digital Library
[News Clip: DART]
Video footage from the KXAS-TV/NBC station in Fort Worth, Texas, covering a news story about the opening of a 3-mile stretch of train service in Oak Cliff area of Dallas and 3 other stations. Interviews with people about the changes it will give to the community. The story aired at 6pm.
Date:
May 31, 1997
Creator:
KXAS-TV (Television station : Fort Worth, Tex.)
Object Type:
Video
System:
The UNT Digital Library
[News Clip: DART]
Video footage from the KXAS-TV/NBC station in Fort Worth, Texas, covering a news story about the opening of a 3-mile stretch of train service in Oak Cliff area of Dallas and 3 other stations. Interviews with people about the changes it will give to the community. Includes firework celebration. The story aired at 10pm.
Date:
May 31, 1997
Creator:
KXAS-TV (Television station : Fort Worth, Tex.)
Object Type:
Video
System:
The UNT Digital Library
[News Clip: Mayor Conference]
B-roll video footage from the KXAS-TV/NBC station in Fort Worth, Texas, of Dallas mayor Ron Kirk sitting down with individuals having inaudible discussions. This story aired at 6:00 P.M.
Date:
May 31, 1997, 6:00 p.m.
Creator:
KXAS-TV (Television station : Fort Worth, Tex.)
Object Type:
Video
System:
The UNT Digital Library
[News Clip: Verdict Watch]
Video footage from the KXAS-TV/NBC station in Fort Worth, Texas, to accompany a news story.
Date:
May 31, 1997, 6:00 p.m.
Creator:
KXAS-TV (Television station : Fort Worth, Tex.)
Object Type:
Video
System:
The UNT Digital Library
[Pangburn Family Videos, No. 20 - First Flight Picnic]
This home movie excerpt documents the 1997 First Flight picnic and includes footage of a helicopter landing.
Date:
May 31, 1997
Creator:
Pangburn
Object Type:
Video
System:
The Portal to Texas History
Pawhuska Journal-Capital (Pawhuska, Okla.), Vol. 87, No. 44, Ed. 1 Saturday, May 31, 1997
Semiweekly newspaper from Pawhuska, Oklahoma that includes local, state, and national news along with advertising.
Date:
May 31, 1997
Creator:
Gann, Sherry
Object Type:
Newspaper
System:
The Gateway to Oklahoma History
Altus Times (Altus, Okla.), Vol. 97, No. 65, Ed. 1 Friday, May 30, 1997
Daily newspaper from Altus, Oklahoma that includes local, state, and national news along with advertising.
Date:
May 30, 1997
Creator:
Cole, Carol
Object Type:
Newspaper
System:
The Gateway to Oklahoma History
Application of powder metallurgy techniques for the development of non-toxic ammunition. Final CRADA report
The purpose of the Cooperative Research and Development Agreement (CRADA) between Martin Marietta Energy Systems, Inc., and Delta Frangible Ammunition (DFA), was to identify and evaluate composite materials for the development of small arms ammunition. Currently available small arms ammunition utilizes lead as the major component of the projectile. The introduction of lead into the environment by these projectiles when they are expended is a rapidly increasing environmental problem. At certain levels, lead is a toxic metal to the environment and a continual health and safety concern for firearm users as well as those who must conduct lead recovery operations from the environment. DFA is a leading supplier of high-density mixtures, which will be used to replace lead-based ammunition in specific applications. Current non-lead ammunition has several limitations that prevent it from replacing lead-based ammunition in many applications (such as applications that require ballistics, weapon recoil, and weapon function identical to that of lead-based ammunition). The purpose of the CRADA was to perform the research and development to identify cost-effective materials to be used in small arms ammunition that eventually will be used in commercially viable, environmentally conscious, non-lead, frangible and/or non-frangible, ammunition.
Date:
May 30, 1997
Creator:
Lowden, R. & Kelly, R.
Object Type:
Report
System:
The UNT Digital Library
The Baytown Sun (Baytown, Tex.), Vol. 75, No. 180, Ed. 1 Friday, May 30, 1997
Daily newspaper from Baytown, Texas that includes local, state, and national news along with advertising.
Date:
May 30, 1997
Creator:
Dobbs, Gary
Object Type:
Newspaper
System:
The Portal to Texas History
BIOREMEDIATION TECHNIQUES ON CRUDE OIL CONTAMINATED SOILS IN OHIO. Final report includes the quarterly report that ended 12/31/1996
The purpose of this study is to define the optimum limits of chemical and physical conditions that reduce soil salinity and maximize indigenous aerobic microbiological populations in the bioremediation of oil field waste solids. Specifically, the study centers around treatment of surface contained oily waste having low density and limited solubility in water. Successful remediation is defined by total petroleum hydrocarbon (TPH) reduction to 1% and no hydrocarbon or salinity impact on ground water resources. The Department of Energy, the US Environmental Protection Agency and the Interstate Oil and Gas Compact Commission have encouraged oil and gas producing states to identify and develop improved methods such as this to reduce, recycle or treat solid waste generated with the exploration and development of domestic petroleum resources (IOGCC, 1995). With encouragement and funding assistance through the Department of Energy, Ohio is developing these bioremediation practices to protect soil and water resources. Ohio produced 8,300,000 barrels of crude oil in 1996 from wells operated by 4310 registered owners (ODNR, 1996). Good well site housekeeping can minimize spills, however accidental spills inevitably occur with oil production of this magnitude. Development of sound environmental and economical clean-up procedures is essential.
Date:
May 30, 1997
Creator:
Hodges, David A. & Simmers, Richard J.
Object Type:
Report
System:
The UNT Digital Library
The Boerne Star (Boerne, Tex.), Vol. 93, No. 43, Ed. 1 Friday, May 30, 1997
Semiweekly newspaper from Boerne, Texas that includes local, state, and national news along with advertising.
Date:
May 30, 1997
Creator:
Aldridge, Leon & D'Amico, Rob
Object Type:
Newspaper
System:
The Portal to Texas History
Charon's Garden
Photograph of a scene in Charon's Garden, in the Wichita Wildlife Refuge.
Date:
May 30, 1997
Creator:
Argo, Jim
Object Type:
Photograph
System:
The Gateway to Oklahoma History
Charon's Garden
Photograph of a scene in Charon's Garden, in the Wichita Wildlife Refuge.
Date:
May 30, 1997
Creator:
Argo, Jim
Object Type:
Photograph
System:
The Gateway to Oklahoma History
Charon's Garden
Photograph of a scene in Charon's Garden, in the Wichita Wildlife Refuge.
Date:
May 30, 1997
Creator:
Argo, Jim
Object Type:
Photograph
System:
The Gateway to Oklahoma History
Charon's Garden
Photograph of a scene in Charon's Garden, in the Wichita Wildlife Refuge.
Date:
May 30, 1997
Creator:
Argo, Jim
Object Type:
Photograph
System:
The Gateway to Oklahoma History
Charon's Garden
Photograph of a scene in Charon's Garden, in the Wichita Wildlife Refuge.
Date:
May 30, 1997
Creator:
Argo, Jim
Object Type:
Photograph
System:
The Gateway to Oklahoma History
Charon's Garden
Photograph of a scene in Charon's Garden, in the Wichita Wildlife Refuge.
Date:
May 30, 1997
Creator:
Argo, Jim
Object Type:
Photograph
System:
The Gateway to Oklahoma History