Considering the explanations of schizophrenia that presume schizophrenia spectrum disorders (e.g., schizotypal personality disorder, schizoaffective disorder, etc.) to be genetically related to schizophrenia, the purpose of this study was to investigate the attention and information processing abilities of individuals who have been identified as schizotypal or psychosis-prone (i.e., schizophrenia spectrum functioning in individuals who do not have schizophrenia). Research indicates that persons identified as psychosis-prone may show attention and information processing deficits similar to individuals with schizophrenia. The identification and description of individuals who later decompensate into schizophrenia would advance the understanding of schizophrenia and its causes. The Chapman's PER-MAG scale (Perceptual Aberration-Magical Ideation) was used to identify 35 hypothetically psychosis-prone college students (schizotypy group) and 42 normal college students (nonschizotypy group) out of the 806 volunteer subjects. Their attention and information processing abilities were measured by COGLAB (a multiparadigmatic cognitive test battery that represents a continuum of cognitive functions, from preattentional to attentional, to conceptual). Their social adjustment was measured by the Premorbid Adjustment Scale (PAS). The hypotheses of the study were that the hypothetically psychosis-prone subjects would perform poorer than controls on COGLAB measures and that COGLAB measures of a more molar nature would better predict social adjustment …

Stress plays a key role in our daily lives, influencing our emotional state, productivity, and health. One particular role in life, being a parent, has attracted significant attention in the research world in terms of the amount of stress parents experience in relation to different aspects of being parents. A life change that many parents, particularly mothers, are experiencing in increasing numbers is their return to college. This study compared reports of parenting stress and perceptions of the family environment between two groups of mothers. The first is a group of 32 mothers who were working 30 or more hours a week outside the home and were not enrolled in college while the second group consists of 31 mothers who were in college full-time and working less than 10 hours a week outside the home. All of the mothers were between the ages of 25 and 45 and had at least one child between the ages 5 and 12 years old. In both groups the mothers verified that their child(ren) was (were) without any diagnosis of an emotional, behavioral, or learning problem. A series of one-way multivariate analysis of variance (MANOVAs) were performed. Results indicated there were no significant group …

The purpose of the present study was to compare the number of perseverations on fused (no delay) versus unfused (0.5 msec delay) CV-DL tasks with measures on a battery of executive functions across three groups: Schizophrenics (SCZ), Manic-Depressives (MD), and normal controls (NC).

Review of previous research on cultural differences in pain experience and/or pain behavior revealed that cultural affiliation affects pain perception and response. Unfortunately, the many inconsistent findings in the literature on cultural differences in pain experience and behavior have made interpretations and comparisons of results problematic. These inconsistent findings could be attributed to variations in acculturation level among cultural groups. The purpose of this study was to investigate cultural differences in pain experience (assessed by McGill Pain Questionnaire, the Box Scale, the Headache Pain Drawing, and the Headache Questionnaire) and pain behavior (measured by determining medication use and interference of daily functioning due to headaches) among Mexican (n = 43), Mexican American (n = 36), and Anglo American (n = 50) female chronic headache pain sufferers. The contribution of acculturation to differences in pain experience and behavior among cultural groups was measured by the Acculturation Rating Scale for Mexican Americans. The three cultural groups of women significantly differed on pain experience and pain behavior. Specifically, Mexican women experienced their headache pain more intensely, severely, and emotionally than Mexican American and Anglo American women. Furthermore, Mexican women were more willing to verbally express their pain than the other two groups. As …

This cross-sectional study compared three groups of grandparents, two custodial and one noncustodial, to identify and delineate the unique challenges and expectations faced by custodial grandparents due to their nontraditional roles while attempting to disentangle grandparental role demands from child-specific problems as sources of distress. Those grandparents raising grandchildren demonstrating neurological, physical, emotional, or behavioral problems exhibited the most distress, the most disruption of roles, and the most deteriorated grandparent-grandchild relationships. Although the custodial grandparents raising apparently normal grandchildren demonstrated less distress, less disruption of roles, and less deterioration of the grandparent-grandchild relationship than those grandparents raising grandchildren displaying problems, they still demonstrated higher levels than did traditional grandparents. Those grandparents who reported fewer resources, demonstrated poor attitudes regarding seeking mental health services, and reported raising grandchildren displaying problems had the lowest levels of adjustment.

Thirty one students with learning disabilities (LD) and/or with Attention Deficit Hyperactivity Disorder (ADHD) completed a combined Academic Attributional Style and Coping with Academic Failures Questionnaire. The reformulated learned helplessness model (Abramson, Seligman, & Teasdale, 1978) predicted that students with negative attributional styles (i.e., internal-stable-global attributions) experienced motivational, cognitive, and emotional deficits. The present study examined college achievement (grade point average) of students with LD and/or ADHD. The Prediction that students with LD and/or ADHD with negative attributional styles would achieve less academic success than comparable students with positive attributional styles (i.e., extenal-unstable-specific attributions) was supported by the research results.

The present study was conducted to clarify and expand knowledge of cognitive functioning in chronic schizophrenia patients (N=21) as compared to a bipolar group (N=20) and a normal group (N=20).

Ketamine and phencyclidine (PCP) are noncompetitive antagonists of the N-methyl-D-aspartate (NMDA) type of ligand-gated glutamate receptors. Both agents have high abuse liability, and may produce dependence. Tolerance to the reinforcing effects of drugs of abuse is widely regarded as a key component of the dependence process. Therefore, the present study was conducted to examine whether tolerance develops to the reinforcing effects of ketamine, and whether PCP and dizocilpine, a noncompetitive NMDA antagonist with negligible abuse liability, produce cross-tolerance to the reinforcing effects of ketamine. Further, identification of the neural mechanisms that underlie tolerance to the reinforcing effects of drugs may yield information regarding drug dependence.

Children who have received radiation therapy for the treatment of brain tumors have been shown to experience neurocognitive deficits which appear to increase over time. The purpose of this study was to examine the memory functioning of 22 children irradiated for brain tumor and 22 healthy children of the same age who had not received irradiation. Subjects were administered a brief form of the WISC-III, to obtain an IQ, and the Wide Range Assessment of Memory and Learning (WRAML), to evaluate visual and verbal memory. Results indicated that, although there were no significant differences between the IQ scores of healthy children and children who had been irradiated, children who have received radiation therapy for brain tumor evidence memory deficits which effect visual and verbal memory abilities. Among the children who had been irradiated, as time since treatment increased, visual memory and overall memory functioning appeared to decline. Findings also suggested that children who received total tumor resection may evidence greater memory deficits than those who received only a partial resection. Visual memory was more closely related to IQ in the children irradiated for brain tumor than in the healthy children. The overall importance of research with this population lies in …

This study examined the neurocognitive skills, incidence of mild head injury, incidence of learning disabilities, and study habits among college students with grade point average of 2.00 or below (N = 25) as contrasted with college students with grade point average above 2.00 (N = 70). The intent of this research was to extend the work of Segalowitz and Brown (1991) and Segalowitz and Lawson (1993) who found significant associations between reported history of mild head injury and developmental disabilities among high school and college samples. MANOVAs conducted on measures of academic achievement, global cognitive skills, verbal and nonverbal memory, motor and tactile functioning, and study habits did not discriminate between probationary and non-probationary students. Probationary and non-probationary students also did not differ with regard to incidence of reported head injury, frequency of diagnosed learning disabilities, and study habits. Measures of neurocognitive functioning and study habits did not contribute to the prediction of grade point average over and above that predicted by Scholastic Aptitude Test composite score. Several exploratory analyses were performed examining the relationship between study habits and neurocognitive skills. Gender differences, implications for future research and development of study skills courses, and limitations of this study were discussed.

Neuronal histamine(HA) may play a role in memory processing. This hypothesis is based upon evidence that the action of histamine at central H1 and H2 histamine receptor sites has been shown to modulate memory of rats and mice in adversely-motivated tasks. The purpose of this study was to test this hypothesis more thoroughly in mice using two distinct approaches to neuronal HA manipulation. One approach involved the use of new pharmacological agents which act at the histamine H3 receptor. It has been demonstrated that the selective H3 antagonist thioperamide increases HA release in the brain of mice whereas the H3 agonist imetit decreases HA release via modulation of presynaptic H3 autoreceptors. It was expected that an increase in neuronal HA via the autoreceptor mechanism would result in facilitation of memory processing whereas a decrease in HA release would disrupt memory processing. The second approach involved the manipulation of cerebral HA levels via the specific enzyme inhibiting compounds alpha-flouromethylhistidine (alpha-FMH), a potent neuronal HA depleter and metoprine, a histamine-methyl transferase inhibitor which results in accumulation of neuronal HA. Again, effects of increased HA due to metoprine and decreased HA levels due to alpha-FMH were expected to facilitate and disrupt memory processing …

Stress responses and coping strategies were assessed for 155 fire fighters who worked during and immediately following Hurricane Andrew in Dade County, Florida in 1992. The participants were surveyed approximately two months after the hurricane, and again one year following the hurricane. The purpose of this study was to evaluate the relationship between the amount of emotional social support received and the amount of symptomatology the participants experienced. This study also introduced empathy as a form of perceived emotional social support and examined the relationship between the empathy felt by the participants and the symptomatology they experienced. For this study, empathy was defined as a participant's ratings of feeling that others truly understand what he or she has been through and is feeling. While other forms of received motional social support were related to an increase in symptomatology, more empathy was related to less symptomatology, in some cases significantly.