This report reviews international research activities in the field of neurotoxicology that will provide a broad overview of research dealing with neurotoxic chemicals that may represent a health hazard to human population.

This report discusses the biotechnology development, government, research institutes and industry and finance in the following countries: Singapore, Thailand, South Korea, and Taiwan.

This report discusses the biotechnology in the following countries: Australia, Brazil, Canada, Denmark, Ireland, Japan, Korea, Netherlands, Switzerland, and United Kingdom.

This report examines how the economic environment of the United States can be made more conducive to improving manufacturing performance. It considers how Federal institutions, in cooperation with industry, can develop competitiveness strategies for high-tech, fast growing industries; and how trade, financial, and technology policies could be combined into a strategic competitiveness policy.

This report is a comprehensive look at the problem as we now know it, the public concerns about the problem, and DOE’s plans for addressing it. It focuses especially on the need for additional attention to those areas which DOE has neither the capability nor the credibility to handle.

This report examines the potential and limitations of cooperative aerial surveillance as a means of supporting the goals of a variety of international agreements. It surveys the types of aircraft and sensors that might be used. It reviews the status of and issues raised by the Open Skies Treaty negotiations as an extended example of an aerial surveillance regime. The report concludes with a quantitative analysis of one possible use of cooperative over flights: the search for potential arms control violations.

This report identifies several immediate steps the Federal Government could take. First, new environmental standards, population shifts, and industrial changes have transformed the nature of many public works problems, and Federal programs must be refocused to fit the new circumstances. Second, if we expect to maintain our economic health, the Nation must increase its investment in public works, despite budget dilemmas.

This paper presents the status of national efforts to cleanup dioxin-contaminated sites and the technologies that have been used, proposed, and researched. It covers thermal and nonthermal treatment techniques as well as approaches such as stabilization and storage. It discusses the development of these technologies as well as advantages and disadvantages of their use.

This report focuses on the Federal Government, the Nation’s largest single energy consumer, in terms of the opportunities and constraints for the use of energy efficient technologies. Energy efficient technologies could greatly reduce energy demand growth and spending in the United States and lessen environmental impacts while increasing productivity. Yet, in today’s public and private markets, adoption rates for many of these technologies are low. This report reviews past and current efforts to improve Federal energy efficiency and discusses policy options that could accelerate the adoption of these measures by the Federal Government.

This report, the first of two, was prepared in response to the requesting committees’ interest in receiving an interim product. It examines how energy is supplied and used in developing countries, and how energy use is linked with economic and social development and environmental quality.

The report provides a broad overview of energy choices facing the Nation. It is not an exhaustive analysis of any one technology; rather, it draws together the main themes of OTA reports from the past 16 years, and other documents, into an outline of the main directions the country could follow.

This report, the result of an assessment of the potential for automation and robotics technology to assist in the exploration of the Moon and Mars, raises a number of issues related to the goals of the U.S. civilian space program. Among other things, the report discusses how greater attention to automation and robotics technologies could contribute to U.S. space exploration efforts.

This report analyzes what OTA identifies as four pressing challenges for the research system i-n the 1990s: setting priorities in tiding, understanding trends in research expenditures, preparing human resources for the future research work force, and supplying appropriate data for ongoing research decision making. Managing the Federal research system requires more than funding; it means devising ways to retain the diversity and creativity that have distinguished U.S. contributions to scientific knowledge.

This report, the final product of OTA’s assessment on international collaboration in defense technology, explores the form and dynamics of the international defense industry, the intricacies of technology transfer and equipment sales, and the implications for U.S. policy.

This background paper, which describes the state-of the- art of identifying substances that can harm the immune system, represents one response to the committee’s request. Chapter 2 provides basic information about the principal components of the immune system and the general consequences that stem from perturbations to it. Chapter 3 describes methods for evaluating chemical immunotoxicity and reports on some known or suspected immunotoxicants. Chapter 4 summarizes Federal research and regulatory activities related to immunotoxicity.

This OTA report responds to a request by the Senate Committee on Energy and Natural Resources to examine the fuel economy potential of the U.S. fleet and to assist Congress in establishing new fuel economy standards.

This report describes, documents, and analyzes available data about two key waste management problems at the Department of Energy Weapons Complex—those of high-level radioactive waste and transuranic waste. The paper is organized in two chapters—” Chapter 1: Managing High Level Waste’ and ‘Chapter 2: Managing Transuranic Waste. ” Each chapter contains a summary overview followed by a discussion and analysis of important areas in the waste management problem that the DOE faces at present and in its future operations.

This OTA Background Paper presents the results of a survey of 1,500 U.S. companies, the 50 largest utilities, and the largest unions. The survey was designed to obtain information about the types of medical monitoring and screening done in the United States and the extent of their use. OTA finds that virtually all large U.S. employers use some of these tests.

This report analyzes various technologies that may be important for future advances in miniaturization. Current research in the United States and other nations is pushing the limits of miniaturization to the point that structures only hundreds of atoms thick will be commonly manufactured. Researchers studying atomic and molecular interactions are continuing to push the frontiers, creating knowledge needed to continue progress in miniaturization. Scientists and engineers are creating microscopic mechanical structures and biological sensors that will have novel and diverse applications.

This report discusses the major issues surrounding the reauthorization of highway and transit legislation is laid out and four illustrative types of surface transportation programs are presented in chapters 1 and 2. Chapter 3 is devoted to the discussion of motor carrier programs, with special attention to issues related to longer combination trucks.

This background paper discusses the legacy of 40 years of U.S. university/AID collaboration, and examines new opportunities for U.S. university participation in development assistance.

Common issues for these systems include their possible contributions to improving mobility in congested corridors, U.S. technology leadership, the Federal role in transportation research and development, and institutional and community barriers to major, new infrastructure programs. Moreover, some Federal financing is likely to be required if commercial maglev or tiltrotor technologies are to be developed by U.S. industry over the next decade. Congress will need to clarify its objectives for supporting or encouraging these technologies before it can make wise decisions on when or whether to undertake substantial, long-term Federal programs in support of either or both of them. This report identifies several funding and management options for consideration if such goals are established.

In 1984, the year after cyclosporine made its debut onto the health care market, OTA reported to Congress on the likely benefits of the drug for Medicare kidney transplant recipients. The present report, requested by the Senate Committee on Finance in the wake of the repeal of the Medicare Catastrophic Coverage Act, examines Medicare’s current immunosuppressive drug coverage dilemma and the policy tradeoffs it entails for the 1990s.

The report concludes that, based on today’s research findings, bST poses no additional risk to consumers and does not produce adverse health effects to cows. However, if approved by FDA, bST will accelerate trends that already put additional economic stress on dairy farm operators in many areas of the country. Other new technologies that may become available during the decade may also have similar impacts as bST and raise similar issues. The industry in the decade of the 1990s will be at a crossroad with important decisions concerning new technologies and public policies.