How to prevent the non-medical use of dependency-producing drugs has been a public policy concern for at least a century. A large part of the responsibility for controlling such substances has been assumed by the Federal Government. Historically based on decision to restrict availability through a system of close regulation, including selective prohibition, the current Federal anti-drugs strategy lives on activities and programs in five major areas: 1) regulation and other “enforcement” efforts; 2) support for international control and for control efforts of individual drug-producing and drug-transiting countries; 3) education and other prevention activities; 4 ) treatment and rehabilitation for drug-dependent persons; and ( 5 ) research on drugs , drug dependency, and prevention and treatment methods.