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Synthesis of 1-Amino-2-Hydroxycyclopentanecarboxylic Acid
This investigation involved the synthesis of 1-amino-2-hydroxycyclopentanecarboxylic acid, a potential structural analog of the natural amino acids, serine and threonine. The title compound also includes the structural features present in an established antitumor agent, cycloleucine.
Date:
December 1970
Creator:
Huddle, John David
System:
The UNT Digital Library
Ketene Reactions: I. The Addition of Acid Chlorides to Dimethylketene ; II. The Cycloaddition of Ketenes to Carbonyl Compounds
Part I describes the addition of several acid chlorides to dimethylketene. The resulting 3-ketoacid chlorides were isolated and characterized. Part II describes the cycloaddition of several aldoketenes to chloral. The ketenes were generated in situ by dehydrohalogenation and dehalogenation of appropriately substituted acyl halides.
Date:
December 1970
Creator:
Smith, Larry
System:
The UNT Digital Library
Aromatic Amino Acid Studies
Pyridine ring analogs of the aromatic amino acids phenylalanine and tyrosine were synthesized and studied in microbiological and mammalian systems.
Date:
December 1970
Creator:
Sullivan, Patrick Timothy
System:
The UNT Digital Library