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PP2Cδ inhibits p300-mediated p53 acetylation via ATM/BRCA1 pathway to impede DNA damage response in breast cancer (open access)

PP2Cδ inhibits p300-mediated p53 acetylation via ATM/BRCA1 pathway to impede DNA damage response in breast cancer

Article describes study which indicates that nuclear type 2C protein phosphatase (PP2Cδ) impairs p53 acetylation and DNA damage response by compromising BRCA1 function in breast cancer development.
Date: October 16, 2019
Creator: Li, Qun; Hao, Qiongyu; Cao, Wei; Li, Jieqing; Wu, Ke; Elshimali, Yahya et al.
System: The UNT Digital Library