NIH Clinical Trials: Various Factors Affect Patient Participation (open access)

NIH Clinical Trials: Various Factors Affect Patient Participation

A letter report issued by the General Accounting Office with an abstract that begins "Pursuant to a congressional request, GAO reviewed patient access to clinical trials sponsored by the National Institutes of Health (NIH), focusing on: (1) how health insurers' coverage policies and practices affect patient participation in clinical trials; (2) researchers' experience in enrolling patients for trials sponsored by the National Cancer Institute (NCI) and factors that may explain this experience; and (3) whether NIH has evidence of recent difficulties in enrolling patients in clinical trials."
Date: October 30, 1999
Creator: United States. General Accounting Office.
System: The UNT Digital Library
Petroleum supply monthly, October 1991. [Contains glossary] (open access)

Petroleum supply monthly, October 1991. [Contains glossary]

Data presented in this report describe the supply and disposition of petroleum products in the United States and major US geographic regions. The data series describe production, imports and exports, inter-Petroleum Administration for Defense (PAD) District movements, and inventories by the primary suppliers of petroleum products in the United States (50 States and the District of Columbia). The reporting universe includes those petroleum sectors in Primary Supply. Included are: petroleum refiners, motor gasoline blenders, operators of natural gas processing plants and fractionators, inter-PAD transporters, importer, and major inventory holders of petroleum products and crude oil. When aggregated, the data reported by these sectors approximately represent the consumption of petroleum products in the United States. Data are divided into two sections (1) the Summary Statistics and (2) the Detailed Statistics 14 figs., 56 tabs.
Date: October 30, 1991
Creator: unknown
System: The UNT Digital Library
A guide to using material model No. 11 in NIKE2D: An internal variable, viscoplasticity model (open access)

A guide to using material model No. 11 in NIKE2D: An internal variable, viscoplasticity model

The need to accurately model the superplastic forming process which is highly rate and temperature dependent motivated the evaluation of Bammann's internal variable, viscoplasticity material model. The model is based upon the concepts of unified creep plasticity, but employs a yield surface for efficient implementation into large-scale numerical computer codes. It has proven elsewhere to be quite successful in describing large strain, thermal-mechanical behavior of crystalline materials. Features of the model enable it to simulate the apparent strain-rate behavior exhibited by many metals above one half the melt temperature. It is the efficient incorporation of features that make the model attractive for use in finite element modeling of metal deformation processes. Although this model was implemented into the Lawrence Livermore National Laboratory's NIKE2D finite element program in 1986, there have been no known reports of successful use by NIKE2D users. The purpose of this report is to provide the user the proper format to input model parameters, a procedure for determining appropriate values for material constants from experimental data, and supplemental information on the model relevant to the implementation in the NIKE2D finite element program. Detailed accounts of the theoretical aspects of the model can be found in the cited …
Date: October 30, 1990
Creator: Flower, E. C. & Nikkel, D. J. Jr.
System: The UNT Digital Library
Alternative washing strategy during in-tank precipitation processing (open access)

Alternative washing strategy during in-tank precipitation processing

If late washing of precipitate is available, it is possible to modify the normal washing phase of the ITP process so that tank corrosion is prevented by inhibiting with sodium hydroxide rather than sodium nitrite. Hydroxide inhibition has numerous advantages to a hydroxide/nitrite flowsheet.1 However, the rate of hydroxide depletion due to radiolysis and C0[sub 2] absorption were uncertainties. Based on recent experiments and calculations: hydroxide consumption by radiolysis will be 0.01 molar per month during Tank 49 storage, hydroxide depletion due to C0[sub 2] absorption will vary from 0.0006 to 0.025 molar per month for waste volumes between 50,000 and 1 million gallons and air flowrates between 100 and 200 cfm. A nominal rate of 0.006 molar/month (or less) is expected in Tank 49 after the first two ITP cycles have been completed. A material balance for the ITP process based on hydroxide inhibition has been calculated and the potential savings have been estimated.
Date: October 30, 1992
Creator: Walker, D. D. & Hobbs, D. T.
System: The UNT Digital Library
A coal-fired combustion system for industrial process heating applications (open access)

A coal-fired combustion system for industrial process heating applications

This advanced combustion system research program is for the development of innovative coal-fired process heaters which can be used for high temperature melting, smelting and waste vitrification processes. The process heater concepts to be developed are based on advanced glass melting and ore smelting furnaces developed and patented by Vortec Corporation. The process heater systems to be developed have multiple use applications; however, the Phase III research effort is being focused on the development of a process heater system to be used for producing value added vitrified glass products from boiler/incinerator ashesand industrial wastes. ne primary objective of the Phase III project is to develop and integrate all the system components, from fuel through total system controls, and then test the complete system in order toevaluate its potential marketability. During the current reporting period, three preliminary coal-fired tests were successfully completed. These tests used industrial boiler flyash, sewer sludge ash, and waste glass collet as feedstocks. The coal-fired ash vitrification tests are considered near term potential commercial applications of the CMS technology. The waste glass cullet provided necessary dam on the effect of coal firing with respect to vitrified product oxidation state. Engineering and design activities in support of the …
Date: October 30, 1992
Creator: unknown
System: The UNT Digital Library
Development of biological coal gasification (MicGAS process). Nineth quarterly report, [July--September 1992] (open access)

Development of biological coal gasification (MicGAS process). Nineth quarterly report, [July--September 1992]

Laboratory scale studies examining biogasification of Texas lignite at various coal solids loadings have been completed. Bench scale bioreactors are currently being used to scale up the biogasification process to higher coal solids loadings (5% and 10%) Specific observations reported this quarter are that methane production was not curtailed when B-vitamin solution was not added to the biogasification medium and that aeration of Mic-1 did not sufficiently oxidize the medium to eliminate strict anaerobic bacteria including methanogens.
Date: October 30, 1992
Creator: unknown
System: The UNT Digital Library
Pulsed Atmospheric Fluidized Bed Combustion. Technical Progress Report, July 1993--September 1993 (open access)

Pulsed Atmospheric Fluidized Bed Combustion. Technical Progress Report, July 1993--September 1993

This quarterly report is broken down between design and the status of the fabrication work being performed. The design section is divided between the following sections: Site layout, foundation design, structural design, piping design, pulse combustor components, and electrical & instrumentation design. As reported in the last quarterly report the location area of the PAFBC in the Clemson Energy Facility was inspected with a view to finalize the layout of the PAFBC plant. Some adjustments were made to the layout to accommodate Clemson University`s requirements and the available space. The most important changes are that the boiler and economizer were relocated in the structure above ground level in order to reduce the size of the footprint of the plant. Figure 1 is the plan view of the current layout. Figures 2 through 6 present different elevation views of the layout. The design of foundations for the entire plant is currently being executed by Industra Engineers Inc. of Greenville, SC. The different weights of various equipment located close to each other precludes the provision of independent foundations for each piece of equipment. One monolithic foundation platform for the whole area proves to be more economical for the current layout. In this …
Date: October 30, 1993
Creator: unknown
System: The UNT Digital Library
DC CICC retrofit magnet. Quarterly progress report, July 1992 (open access)

DC CICC retrofit magnet. Quarterly progress report, July 1992

The coil system presented here for the MHD retrofit magnet incorporates many features of the latest in superconducting magnet technology and finite element modeling to create an efficient and viable design concept. At the core of the design is the niobium titanium (NbTi) superconducting Cable-in-Conduit Conductor (CICC). Engineered to create moderately high magnetic fields (up to 8 T) with essentially no power loss, this specific CICC design provides good load carrying capacity, operating margin from a perturbation such as a local heat input, and coil protection in the event of a quench transient. The CICC is wound on a mandrel into long, tapered, saddle shaped single conductor thickness pancakes. By defining the appropriate number of conductor turns in each pancake, the saddle coils can be stacked to form a semi-elliptical winding pack cross section. Extruded aluminum filler blocks are fitted into the steps, at the edge of the pancake and present a smooth surface to the supporting structure. The semi-elliptical conductor array is supported by an identically shaped strap at all locations except where the end turns sweep over the MHD channel. The strap resists the electromagnetic forces tending to separate the coils on each side of the channel. Low …
Date: October 30, 1992
Creator: Myatt, R. L. & Marston, P. G.
System: The UNT Digital Library
A coal-fired combustion system for industrial process heating applications. Quarterly technical progress report, July 1993--September 1993 (open access)

A coal-fired combustion system for industrial process heating applications. Quarterly technical progress report, July 1993--September 1993

This advanced combustion system research program is for the development of innovative coal-fired process heaters which can be used for high temperature melting, smelting and waste vitrification processes. The process heater systems to be developed have multiple use applications; however, the Phase 3 research effort is being focused on the development of a process heater system to be used for producing value added vitrified glass products from boiler/incinerator ashes and industrial wastes. The primary objective of the Phase 3 project is to develop and integrate all the system components, from fuel through total system controls, and then test the complete system in order to evaluate its potential marketability. During the past quarter, the major effort was completing some of the system modification installation designs, completing industry funded testing, developing a surrogate TSCA ash composition, and completing the TSCA ash Test Plan. The installation designs will be used for the equipment modifications planned for the end of CY 93. The industry funded testing consisted of vitrifying Spent Aluminum Potliner (SPL) which is a listed hazardous waste. This testing has verified that SPL can be vitrified into a safe, recyclable glass product. Some results from this testing are provided in Section 2.2.1. …
Date: October 30, 1993
Creator: unknown
System: The UNT Digital Library
Alternative washing strategy during in-tank precipitation processing (open access)

Alternative washing strategy during in-tank precipitation processing

If late washing of precipitate is available, it is possible to modify the normal washing phase of the ITP process so that tank corrosion is prevented by inhibiting with sodium hydroxide rather than sodium nitrite. Hydroxide inhibition has numerous advantages to a hydroxide/nitrite flowsheet.1 However, the rate of hydroxide depletion due to radiolysis and C0{sub 2} absorption were uncertainties. Based on recent experiments and calculations: hydroxide consumption by radiolysis will be 0.01 molar per month during Tank 49 storage, hydroxide depletion due to C0{sub 2} absorption will vary from 0.0006 to 0.025 molar per month for waste volumes between 50,000 and 1 million gallons and air flowrates between 100 and 200 cfm. A nominal rate of 0.006 molar/month (or less) is expected in Tank 49 after the first two ITP cycles have been completed. A material balance for the ITP process based on hydroxide inhibition has been calculated and the potential savings have been estimated.
Date: October 30, 1992
Creator: Walker, D. D. & Hobbs, D. T.
System: The UNT Digital Library
Groundwater transport modeling of constituents originating from the Burial Grounds Complex (open access)

Groundwater transport modeling of constituents originating from the Burial Grounds Complex

The Savannah River Site (SRS), operates a number of sites for the land disposal of various leachable radionuclide, organic, and inorganic wastes. Located within the General Separations Area (GSA) of SRS are the Low Level Radioactive Waste Disposal Facility (LLRWDF) and the Old Burial Ground (OBG). A portion of the LLRWDF has been designated as the Mixed Waste Management Facility (MWMF). The OBG began receiving waste in 1952 and was closed in 1974. Various wastes, including transuranic, intermediate and low level beta-gamma, and solvents, were received during this period of operation. In 1969, prior to the closing of the OBG, a portion of the MWMF/LLRWDF (the MWMF) began receiving waste. GeoTrans, Inc. was contracted by WSRC to conduct a numerical modeling study to assess groundwater flow and contaminant transport in the vicinity of the MWMF in support of an Alternate Concentration Limits demonstration for the Part B permit. The project was divided into two phases: development of a groundwater flow model of the hydrogeologic system underlying the MWMF which includes the entire GSA, and development of a solute transport model to assess migration of 19 designated constituents of concern (COCs) over a period 30 years into the future. The first …
Date: October 30, 1992
Creator: Andersen, P. F.; Shupe, M. G. & Spalding, C. P.
System: The UNT Digital Library
The HILDA program (open access)

The HILDA program

Although this report is called a program document, it is not simply a user`s guide to running HILDA nor is it a programmer`s guide to maintaining and updating HILDA. It is a guide to HILDA as a program and as a model for designing and costing a heavy ion fusion (HIF) driver. HILDA represents the work and ideas of many people; as does the model upon which it is based. The project was initiated by Denis Keefe, the leader of the LBL HIFAR project. He suggested the name HILDA, which is an acronym for Heavy Ion Linac Driver Analysis. The conventions and style of development of the HILDA program are based on the original goals. It was desired to have a computer program that could estimate the cost and find an optimal design for Heavy Ion Fusion induction linac drivers. This program should model near-term machines as well as fullscale drivers. The code objectives were: (1) A relatively detailed, but easily understood model. (2) Modular, structured code to facilitate making changes in the model, the analysis reports, and the user interface. (3) Documentation that defines, and explains the system model, cost algorithm, program structure, and generated reports. With this tool …
Date: October 30, 1991
Creator: Close, E.; Fong, C. & Lee, E.
System: The UNT Digital Library
Use of Cloud Observations and Mesoscale Meteorology Models to Evaluate and Improve Cloud Parameterizations. Technical Progress Report, 1 December 1991--30 November 1992 (open access)

Use of Cloud Observations and Mesoscale Meteorology Models to Evaluate and Improve Cloud Parameterizations. Technical Progress Report, 1 December 1991--30 November 1992

This research program utilizes satellite and surface-derived cloud observations together with standard meteorological measurements to evaluate and improve our ability to accurately diagnose cloud coverage. Results are to be used to compliment existing or future parameterizations of cloud effects in general circulation models, since nearly all cloud parameterizations must specify a fractional area of cloud coverage when calculating radiative or dynamic cloud effects, and current parameterizations rely on rather crude cloud cover estimates. We have compiled and reviewed a list of formulations used by various climate research groups to specify cloud cover. We find considerable variability between formulations used by various climate and meteorology models, and under some conditions, one formulation will produce a zero cloud amount, while an alternate formulation calculates 95% cloud cover under the same environmental conditions. All formulations hypothesize that cloud cover is predominantly determined by the average relative humidity, although some formulations allow local temperature lapse rates and vertical velocities to influence cloud amount.
Date: October 30, 1992
Creator: Walcek, C. J.
System: The UNT Digital Library
Impeachment Grounds: Part I: Pre-Constitutional Convention Materials (open access)

Impeachment Grounds: Part I: Pre-Constitutional Convention Materials

This report is a collection of selected background materials pertinent to the issue of what constitutes impeachable misconduct for purposes of Article II, section 4 of the United States Constitution quoted below. It includes excerpts from Blackstone, Wooddeson, and the impeachment clauses in pre-Constitutional Convention state constitutions.
Date: October 30, 1998
Creator: Doyle, Charles
System: The UNT Digital Library
Portable high-speed biomass processor for Chunkwood (open access)

Portable high-speed biomass processor for Chunkwood

All the design tasks for the Chunker/baler machine have been completed. The multiple blade shearing system and the chunkwood baler were very challenging. I believe if there was a market for chunkwood, the redesigned Chunker would be a viable marketable product. It appears however that at best the market is very limited and would not justify an investment either by me or a possible licensee at this time. I do believe however, that eventually the costs for fossil fuels are going to rise to the point that chunkwood will be a profitable product. When this time arrives, we will have a god machine waiting in the wings to fill this future need.
Date: October 30, 1992
Creator: Aikins, W. A.
System: The UNT Digital Library
Scaleup tests and supporting research for the development of duct injection technology. Final report, Task 4.5 (open access)

Scaleup tests and supporting research for the development of duct injection technology. Final report, Task 4.5

DOE`s Duct Injection Test Facility at Ohio Power Company`s Muskingum River Plant was modified to enable performance of a comprehensive test program concerning duct injection of sorbents for SO{sub 2} control. Injection of slaked lime slurries and injection of dry calcium hydroxide powder with humidification were carried out under a variety of process conditions. Slaked lime slurry injection as found to be superior in both operational reliability and S0{sub 2} removal capability compared with dry hydrated lime injection with humidification. Calcium utilization of 50% was achieved with 50% S0{sub 2} removal at the ESP outlet with recycle of unreacted sorbent collected in the precipitatorhoppers. Electrostatic precipitator collection performance was found to be highly variable with sorbent injection, especially with close approach to saturation temperatures and high inlet mass loadings. Small-scale tests with a fabric filter in parallel with the precipitator indicated 5 to 10% more S0{sub 2} removal could be obtained across the fabric filter than the ESP for all test conditions. Over 95% S0{sub 2} removal was achieved with the fabric filter using a two stage cooling process in which the filter was cooled below the operating temperature ofthe duct spray dryer.
Date: October 30, 1992
Creator: Felix, L. G.; Gooch, J. P.; Merritt, R. L.; Klett, M. G.; Demian, A. G. & Hunt, J. E.
System: The UNT Digital Library
A coal-fired combustion system for industrial process heating applications. Quarterly technical progress report, July 1992--September 1992 (open access)

A coal-fired combustion system for industrial process heating applications. Quarterly technical progress report, July 1992--September 1992

This advanced combustion system research program is for the development of innovative coal-fired process heaters which can be used for high temperature melting, smelting and waste vitrification processes. The process heater concepts to be developed are based on advanced glass melting and ore smelting furnaces developed and patented by Vortec Corporation. The process heater systems to be developed have multiple use applications; however, the Phase III research effort is being focused on the development of a process heater system to be used for producing value added vitrified glass products from boiler/incinerator ashesand industrial wastes. ne primary objective of the Phase III project is to develop and integrate all the system components, from fuel through total system controls, and then test the complete system in order toevaluate its potential marketability. During the current reporting period, three preliminary coal-fired tests were successfully completed. These tests used industrial boiler flyash, sewer sludge ash, and waste glass collet as feedstocks. The coal-fired ash vitrification tests are considered near term potential commercial applications of the CMS technology. The waste glass cullet provided necessary dam on the effect of coal firing with respect to vitrified product oxidation state. Engineering and design activities in support of the …
Date: October 30, 1992
Creator: unknown
System: The UNT Digital Library
Full Scale Regenerable HEPA Filter System Design (open access)

Full Scale Regenerable HEPA Filter System Design

None
Date: October 30, 1999
Creator: Ramons, Gil
System: The UNT Digital Library
SECOND GENERATION ADVANCED REBURNING FOR HIGH EFFICIENCY NOx CONTROL (open access)

SECOND GENERATION ADVANCED REBURNING FOR HIGH EFFICIENCY NOx CONTROL

This project is designed to develop a family of novel NO{sub x} control technologies, called Second Generation Advanced Reburning which has the potential to achieve 90+% NO{sub x} control in coal fired boilers at a significantly lower cost than SCR. The fourth reporting period in Phase II (July 1--September 30, 1998) included experimental activities at pilot scale and combined chemistry-mixing modeling on gas reburning. The pilot scale tests reported in previous Quarterly Reports QR-2 and QR-3 were continued. The objective was to simulate furnace conditions at the Greenidge boiler No. 6 owned and operated by NYSEG and to improve the process performance. The tests were conducted in EER's Boiler Simulator Facility (BSF). During the reporting period, measurements of CO and ammonia emissions were conducted for reburn + SNCR conditions, as well as tests on the effect of sodium on NO{sub x} control efficiency. Exhaust levels of CO remained below 100 ppm in all tests. Prospective process conditions for the full-scale facility have been identified that can provide over 80% NO{sub x} reduction while maintaining ammonia slip below 4 ppm. Addition of sodium resulted in NO{sub x} control improvement of about 7-10 percentage points. The objective of modeling work was to …
Date: October 30, 1998
Creator: unknown
System: The UNT Digital Library
Test Plan for K Basin floor sludge consolidated sampling equipment (open access)

Test Plan for K Basin floor sludge consolidated sampling equipment

The purpose of this document is to provide the test procedure for the function and acceptance testing of the K Basin Floor Sludge Consolidated Sampling Equipment. This equipment will be used to transfer K Basin floor sludge to a sludge sampling container for subsequent shipment to an analysis or testing facility. This equipment will provide sampling consistent with data quality objectives and sampling plans currently being developed.
Date: October 30, 1998
Creator: OLIVER, J.W.
System: The UNT Digital Library
Economic Recovery of Oil Trapped at Fan Margins Using High Angle Wells Multiple Hydraulic Fractures (open access)

Economic Recovery of Oil Trapped at Fan Margins Using High Angle Wells Multiple Hydraulic Fractures

This project attempts to demonstrate the effectiveness of exploiting thin-layered, low-energy deposits at the distal margin of a prograding turbidite complex through the use of hydraulically fractured horizontal or high-angle wells. The combination of a horizontal or high-angle well and hydraulic fracturing will allow greater pay exposure than can be achieved with conventional vertical wells while maintaining vertical communication between thin interbedded layers and the wellbore. A high-angle well will be drilled in the fan-margin portion of a slope-basin clastic reservoir and will be completed with multiple hydraulic-fracture treatments. Geologic modeling, reservoir characterization, and fine-grid reservoir simulation will be used to select the well location and orientation. Design parameters for the hydraulic-fracture treatments will be determined, in part, by fracturing an existing test well. Fracture azimuth will be predicted by passive seismic monitoring of a fracture-stimulation treatment in the test well using logging tools in an offset well.
Date: October 30, 1997
Creator: Laue, Mike L.
System: The UNT Digital Library
Practical superconductor development for electrical power applications quarterly report for the period ending September 30, 1997 (open access)

Practical superconductor development for electrical power applications quarterly report for the period ending September 30, 1997

This is a multiyear experimental research program focused on improving relevant material properties of high-T{sub c} superconductors and on development of fabrication methods that can be transferred to industry for production of commercial conductors. The development of teaming relationships through agreements with industrial partners is a key element of this program. Recent work on strain tolerance of Bi-2223 tapes, AC downlink construction, fundamental studies of flux pinning, and application of coils from powder-in-tube tapes to particle detectors is discussed.
Date: October 30, 1997
Creator: unknown
System: The UNT Digital Library
Aspen Process Flowsheet Simulation Model of a Battelle Biomass-Based Gasification, Fischer-Tropsch Liquefaction and Combined-Cycle Power Plant (open access)

Aspen Process Flowsheet Simulation Model of a Battelle Biomass-Based Gasification, Fischer-Tropsch Liquefaction and Combined-Cycle Power Plant

This study was done to support the research and development program of the National Renewable Energy Laboratory (NREL) in the thermochemical conversion of biomass to liquid transportation fuels using current state-of-the-art technology. The Mitretek study investigated the use of two biomass gasifiers; the RENUGAS gasifier being developed by the Institute of Gas Technology, and the indirectly heated gasifier being developed by Battelle Columbus. The Battelle Memorial Institute of Columbus, Ohio indirectly heated biomass gasifier was selected for this model development because the syngas produced by it is better suited for Fischer-Tropsch synthesis with an iron-based catalyst for which a large amount of experimental data are available. Bechtel with Amoco as a subcontractor developed a conceptual baseline design and several alternative designs for indirect coal liquefaction facilities. In addition, ASPEN Plus process flowsheet simulation models were developed for each of designs. These models were used to perform several parametric studies to investigate various alternatives for improving the economics of indirect coal liquefaction.
Date: October 30, 1998
Creator: unknown
System: The UNT Digital Library
Geological and petrophysical characterization of the Ferron Sandstone for 3-D simulation of a fluvial-deltaic reservoir. Quarterly progress report, July 1--September 30, 1995 (open access)

Geological and petrophysical characterization of the Ferron Sandstone for 3-D simulation of a fluvial-deltaic reservoir. Quarterly progress report, July 1--September 30, 1995

The objective of this project is to develop a comprehensive, interdisciplinary, and quantitative characterization of a fluvial-deltaic reservoir which will allow realistic inter-well and reservoir-scale modeling to be constructed for improved oil-field development in similar reservoirs world-wide. The geological and petrophysical properties of the Cretaceous Ferron Sandstone in east-central Utah will be quantitatively determined. Both new and existing data will be integrated into a three-dimensional representation of spatial variations in porosity, storativity, and tensorial rock permeability at a scale appropriate for inter-well to regional-scale reservoir simulation. Results could improve reservoir management through proper infill and extension drilling strategies, reduction of economic risks, increased recovery from existing oil fields, and more reliable reserve calculations. Transfer of the project results to the petroleum industry is an integral component of the project. Technical progress this quarter is divided into regional stratigraphy, case studies, stochastic modeling and fluid-flow simulation, and technology transfer activities. The regional stratigraphy of the Ferron Sandstone outcrop belt is being described and interpreted. Detailed geological and petrophysical characterization of the primary reservoir lithofacies typically found in a fluvial-dominated deltaic reservoir, is continuing at selected case-study areas. Interpretations of lithofacies, bounding surfaces, and other geologic information are being combined with permeability …
Date: October 30, 1995
Creator: Allison, M. L.
System: The UNT Digital Library