Targeting the PI3K/Akt signaling pathway in gastric carcinoma: A reality for personalized medicine? (open access)

Targeting the PI3K/Akt signaling pathway in gastric carcinoma: A reality for personalized medicine?

Article reviews the common dysregulation of phosphatidylinositol-3 kinases (PI3K)/Akt/mTOR pathway in gastric cancer (GC) and the various types of single or dual pathway inhibitors under development that might have a superior role in GC treatment.
Date: October 26, 2015
Creator: Singh, Shikha Satendra; Yap, Wei Ney; Arfuso, Frank; Kar, Shreya; Wang, Chao; Cai, Wanpei et al.
System: The UNT Digital Library