O-Acetylserine Sulfhydrylase (OASS) is a pyridoxal phosphate enzyme that catalyzes the reaction of O-acetyl-Lserine with sulfide to give L-cysteine. OASS is present as two isoforms, designated -A and -B. The kinetic mechanism of OASS-A is well known and there is also much known concerning the acid-base chemistry of the enzyme. However, little is known concerning the location of the rate determining steps, the sequencing of chemical steps that occur at the active site, or the nature of the rate determining transition states. The studies performed to help elucidate these aspects of the OASS-A mechanism included determination of the thermodynamics of both half reactions, along with studies utilizing substrate analogs of OAS halting the reaction at specific points along the reaction pathway allowing the identification of reaction intermediates. The free energy change of the first half reaction was shown to be -5.7 Kcal/mole while the second half reaction was shown to be, for all intents and purposes, irreversible. Intermediates along the reaction pathway that have been previously identified include the internal Schiff base and the a-aminoacrylate. The external Schiff base was identified using the analogs cysteine, alanine, and glycine while the geminal diamine was identified using the analog serine. Formation of …

Prolonged exposure to microgravity is known to invoke physiological changes which predispose individuals to orthostatic intolerance upon readaptation to the earth's gravitational field. Attenuated baroreflex responsiveness has been implicated in contributing to this inability to withstand orthostatic stress. To test this hypothesis, eight individuals were exposed to 15 days of simulated microgravity exposure using the 6° head-down bed rest model. Prior to, and after the simulated microgravity exposure, the following were assessed: a) aortic baroreflex function; b) carotid baroreflex function; c) cardiopulmonary baroreflex function; and d) the degree of interaction between the cardiopulmonary and carotid baroreflexes.

The purpose of the present cross-sectional study was to examine the effects of ambiguity of loss and type of caregiver-to-patient relationship on anticipatory grief, negative physical and psychological outcomes associated with grief, and boundary ambiguity in family caregivers of chronically ill patients. Questionnaires were completed by 23 parents of ill children and 30 spouses of ill mates. Using an original and a revised concept for level of ambiguity, partial support was found for the prediction that parents and spouses in high ambiguity of loss circumstances would report more anticipatory grief than those in low ambiguity ones. Contrary to prediction, a slight but nonsignificant trend occurred for parents and spouses in low ambiguity situations to report more negative physical and psychological effects associated with grief as well. Level of ambiguity was not found to impact boundary ambiguity as had been hypothesized. Spouses reported more boundary ambiguity than parents, regardless of level of ambiguity of the loss. Contrary to prediction that parents would report less anticipatory grief and more negative physical and psychological outcomes than spouses, generally, no significant differences were found between the two groups. However, using the original concept of ambiguity, parents did tend to recall more past grief than …

Animations is a composition in six movements (Fish, Seals, Birds, Cats, Zebras, Snakes) for percussion and computer music on tape. One percussionist performs on various percussion instruments: two suspended cymbals, crotales, triangle, vibraphone, glockenspiel, marimba, three bongos, snare drum, field drum, large tom-tom, bass drum, kettle drum, temple blocks and vibraslap. The computer music on tape employs sampled sounds in a MIDI sequencing environment. The melodic and harmonic materials for the piece are derived from a matrix of twelve heptatonic scales. The individual movements are notated using both traditional and proportional notation systems. The score is 37 pages long with a twenty-two page analysis preceding the score. Animations is approximately nine minutes in duration.

In this dissertation the results of Jerrum and Sinclair on the conductance of Markov chains are used to prove that almost all generalized Steinhaus graphs are rapidly mixing and an algorithm for the uniform generation of 2 - (4k + 1,4,1) cyclic Mendelsohn designs is developed.

In the middle of his career, Arthur Garfield Dove created a smell yet novel body of landscape assemblages. They illustrate Dove's central interest in evoking nature--its motifs and rhythms--through imaginative associations of organic and man-made materials. These works represent Dove's synthesis of contemporary European stylistic and intellectual ideas as well as American philosophies and concerns. They also reflect the influence of Alfred Stieglitz and his circle and the artist Helen Torr, Dove's second wife. This study examines how Dove used a complex interplay of European theory and technique, American ideas and his own nature-based abstract style to create the landscape assemblages, works that are uniquely independent in the history of American art.

The purpose of this study was to ascertain the image of the University of North Texas as perceived by the University Administration and Board of Regents, Texas Higher Education Coordinating Baord and selected Legislators, and the Boards of Directors of the Metroplex area Chambers of Commerce. The significance of the study was to contribute knowledge that could be used to construct a more direct and cost effective marketing plan.

Learning styles and readiness for self-directed learning were identified for 125 adult employees enrolled in self-paced training courses. The success of the self-paced instruction was measured by confidence to perform learned skills on the job. Confidence scores were compared across learning style types and self-directed learning readiness. It was concluded that self-paced training programs can be effective for a variety of learning style preferences. Additionally, adult employees who are highly self-directed will experience greater success in self-paced instruction than those less self-directed. The implication for businesses and academic institutions seeking to employ technology based, self-instructional programs is that a return on investment can be maximized by an examination of the target audience. Training programs which are self-paced may not generate the desired success which will translate into effective job performance for those adults who are not ready for self-directed learning.

This investigation sought to identify sound levels potentially harmful to directors' hearing, and examine the effects of band size, instrumentation, bandroom and playing ability on sound levels. The subjects were 2 elementary, 2 middle, and 4 high school bands, in 7 rooms, 10 to 66 members, and 26 students, beginning and advanced. A sound level meter was used. Sounds were measured in flat and A-weighted decibels. Sounds measured were steady state (>.5 sec.) and impulse (<.5 sec.). Results were compared with safety limits of OSHA, EPA and Baughn's study of safety limits (1966). Results show exceedences of limits used for comparison. Small rehearsal areas and younger players seemed to cause high levels in the tests. Further testing may prove potential hazards.

This thesis is a play for children. The story and the characters were derived from traditional Norwegian fairy tales. The central character is Billikin Whiskers, a billy-goat, who is captured by three trolls--Sparky, Garr and Pragg. The play is set on a mountain in Norway. The central idea of the play is the issue of intelligence--represented by Billikin Whiskers--versus physical strength--symbolized by the trolls.

The conclusion of the First World War brought the resumption of a struggle of a different sort: a battle between government and labor. Throughout 1919, government and labor squared off in a struggle over hours, wages, and nationalization. The Russian Revolution introduced the danger of the bolshevik contagion into the struggle. The first to enter into this conflict with the government were the shop stewards of Belfast and Glasgow. The struggle continued with the continued threats of the Triple Alliance and the police to destroy the power of the government through industrial action. This thesis examines the British labor movement during this revolutionary year in Europe, as well as the government's response to this new danger.

The problem with which this study is concerned is comparative administrative leadership behavior between municipal and university administrators. The specially designed survey instrument elicited respondents' perceptions of their administrative leadership behavior based on the 12 dimensions of the Leader Behavior Description Questionnaire- XII.

Chronic ventricular sympathectomy elicits changes in the coronary circulation, myocardial oxygen consumption and size of infarction resulting fromcoronary occlusion. These changes indicate a change occurring in the basic metabolism of the heart in response to the removal of its sympathetic nervous input. This hypothesis was tested using two groups of dogs, a shamoperated control and a ventricular sympathectomized group. The sympathectomy procedure was an intrapericardial surgical technique which selectively removes ventricular sympathetic input. Four weeks after surgery, left ventricular tissue samples were obtained and rapidly frozen to -80°C. Selected metabolic variables were then compared between the two groups.

The simplicity and ease of use of the Rasch procedure is a decided advantage. The test user needs only two numbers: the frequency of persons who answered each item correctly and the Rasch-calibrated item difficulty, usually a part of an existing item bank. Norms can be computed quickly for any specific group of interest. In addition, once the selected items from the calibrated bank are normed, any test, built from the item bank, is automatically norm-referenced. Thus, it was concluded that the Rasch quick norm procedure is a meaningful alternative to traditional classical true score norming for test users who desire normative data.

This study investigates compliance-gaining rhetoric among Anglo and Mexican-American fourth graders in three schools in north Texas. The children were asked to respond to a scenario and to give a rationale for their persuasive strategies. An analysis of interviews with 52 children indicates that although the children used some similar strategies when attempting to gain compliance from an adult, there are also some significant differences between the two cultural groups.

The purpose of this study was to analyze and compare the values, beliefs, and ideas in school reading textbooks (Readers) in Taiwan and in Texas. It intended to examine the social control function of school Readers, with which a culture deliberately molds its young generation. This study employed primarily qualitative methods. The collection of data used the technique of content analysis, student surveys, and teacher expert panel discussions. The analysis of data followed a constant comparative approach. The themes shared by the two sets of Readers included family, friends, humans and living creatures, political ideals, reading/writing, appreciation of nature, science, indomitable spirit, turning danger into safety, setting goals, education, desirable and undesirable qualities or behaviors. Despite the similarities of these themes, the substance or focus of them may vary. The themes unique to the Texas Readers were content knowledge, cultural diversity, dilemma and choice, observations about people, words, tomorrow's technology, winning, and general truth. The themes unique to the Taiwan Readers included life philosophy, learning, necessary difficulties, sensitivity, and military strategies. The theme occurring most frequently in both sets of Readers was the desirable qualities or behaviors. The values advocated in the Taiwan Readers were idealistic and had a society-centered …

There is a limited amount of research dealing with the wealth effects of sale-and-leaseback transactions, but previous research has focused predominantly on the tax effects of these transactions. The results of these studies have often been in conflict with one another. This dissertation shows that tax effects do play a role in determining the wealth effect of sale-and-leasebacks on stockholders, but there exists a framework of finance research that suggests several other factors could play a determining role as well.

This study reviews the changes in Taiwan's newspaper industry during its current period of transition. Contemporary newspaper development in Taiwan after the lifting of martial law in July 1987 is evaluated in relation to transformations in the newspaper marketplace, journalistic practices, labor relations, and freedom of expression. This study concludes that changes in Taiwan's newspaper business are closely related to changes in the country's political atmosphere. The lifting of the Ban of Newspaper brought freedoms for which journalists had fought for decades; however, journalistic quality has not improved at the same speed. Changes will continue in the journalism industry; whether it grows in a healthy way is a topic for future study.

The primary purpose of this study was to find the content and form of movies which conform to the taste of the majority of Thai audiences and, at the same time, are universal enough to attract international audiences. Because film is an extension of other art forms, this required extensive research into the roots of Thai performing arts.

This study focuses on clarifying the relationships among decentralization, privatization, and economic development in developing countries.

A content analysis was conducted to determine the amount and type of causal explanation included in coverage of the 1992 Los Angeles riots in The New York Times, the Los Angeles Times and The Christian Science Monitor. The data were analyzed to determine whether causal explanations were primarily societal or individual/situational. The primary purpose was to examine whether the press has altered its reporting techniques since the Kerner Commission report criticized the narrow, descriptive-based reporting of the 1960s riots. Study results indicate riot coverage was predominantly descriptive and similar in content to that detailed by the Kerner Commission. The most frequently cited cause was the triggering event, the Rodney King acquittal verdict.

Designs is an algorithmic composition for small orchestra. The main compositional process used involves the realization and implementation of various musical algorithms discussed in the book Composition with Pitch-Classes by theorist/composer Robert Morris.

The study was undertaken: (a) to categorize the contents of educational computing articles using a taxonomy developed by Knezek, Rachlin, and Scannell (1988), (b) to examine the trends in educational computing subject matter addressed in community/junior college journals between 1977 and 1991, and (c) to identify and analyze specific characteristics of contributing authors and their employing institutions which might explain writing and publication biases.

The goal of this thesis is to contribute to the ambitious program of the foundation of developing statistical physics using chaos. We build a deterministic model of Brownian motion and provide a microscpoic derivation of the Fokker-Planck equation. Since the Brownian motion of a particle is the result of the competing processes of diffusion and dissipation, we create a model where both diffusion and dissipation originate from the same deterministic mechanism - the deterministic interaction of that particle with its environment. We show that standard diffusion which is the basis of the Fokker-Planck equation rests on the Central Limit Theorem, and, consequently, on the possibility of deriving it from a deterministic process with a quickly decaying correlation function. The sensitive dependence on initial conditions, one of the defining properties of chaos insures this rapid decay. We carefully address the problem of deriving dissipation from the interaction of a particle with a fully deterministic nonlinear bath, that we term the booster. We show that the solution of this problem essentially rests on the linear response of a booster to an external perturbation. This raises a long-standing problem concerned with Kubo's Linear Response Theory and the strong criticism against it by van …