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Hypoxia-induced reprogramming of the cardiac phenotype in American alligators (Alligator mississippiensis) revealed by quantitative proteomics (open access)

Hypoxia-induced reprogramming of the cardiac phenotype in American alligators (Alligator mississippiensis) revealed by quantitative proteomics

Article describes study which tested if targeted and persistent changes in steady-state protein expression underlie this hypoxic heart phenotype, using isobaric tags for relative and absolute quantitation (iTRAQ) proteomics.
Date: June 13, 2019
Creator: Alderman, Sarah L.; Crossley, Dane A., II; Elsey, Ruth M. & Gillis, Todd E.
System: The UNT Digital Library
The flexibility of proanthocyanidin biosynthesis in plants (open access)

The flexibility of proanthocyanidin biosynthesis in plants

Article presents research that explores proanthocyanidin (PA) biosynthesis routes in plants. The data suggests that different species have evolved different routes for PA biosynthesis.
Date: June 13, 2022
Creator: Lu, Nan; Jun, Ji Hyung; Liu, Chenggang & Dixon, R. A.
System: The UNT Digital Library
CancerNet: a unified deep learning network for pan‑cancer diagnostics (open access)

CancerNet: a unified deep learning network for pan‑cancer diagnostics

Article states that despite remarkable advances in cancer research, cancer remains one of the leading causes of death worldwide. The author's proposed framework for cancer diagnostics detects cancers and their tissues of origin using a unified model of cancers encompassing 33 cancers represented in The Cancer Genome Atlas. Their model exploits the learned features of different cancers reflected in the respective dysregulated epigenomes, holding a great promise in early cancer detection.
Date: June 13, 2022
Creator: Gore, Steven & Azad, Rajeev K.
System: The UNT Digital Library