This report is divided into three major sections analyzing Cuba's political and economic environment, U.S. policy, and selected issues in U.S.-Cuban relations. Legislative initiatives in the 114th Congress are noted throughout the report, and four appendixes provide a listing of enacted measures, bills receiving some action in 2015, bills seeing action in 2016, and additional bills and resolution this Congress.

This report outlines current progress towards establishment of the National Bio- and Agro-Defense Facility (NBAF), presents current and projected funding levels and timelines, and describes policy issues of potential interest to Congress, such as agency coordination, possession of viruses, construction timelines, disposition of PIADC, and community safety concerns.