Article on an integrative analysis of transgenic alfalfa (Medicago sativa L.) suggesting new metabolic control mechanisms for monolignol biosynthesis.

Article on bacterial communities of the coronal sulcus and distal urethra of adolescent males.

Article on elemental concentrations in the seed of mutants and natural variants of Arabidopsis thaliana grown under varying soil conditions.

Article on nutrient-deprivation autophagy factor-1 (NAF-1) and biochemical properties of a novel cellular target for anti-diabetic drugs.

Article on nutrient-deprivation autophagy factor-1 (NAF-1) and biochemical properties of a novel cellular target for anti-diabetic drugs.

Article presenting evidence from GFP fusion experiments that the MtENOD8 protein contains at least three symbiosome targeting domains, including its N-terminal signal peptide (SP).

Article discussing the microbial communities in male first catch urine and how these are highly similar to those paired in urethral swab specimens.

Article on keel petal incision and a simple and efficient method for genetic crossing in Medicago truncatula.

This article describes the design of a GIS and remote sensing based analysis tool called the Water Quality Corridor Management model to identify and prioritize highly functioning riparian ecosystems for the preservation of steam corridor conditions.

Article studying the effect of MS222 on hemostasis in Zebrafish. The authors performed various assays and find that Hct values, the amount of blood collected, bleeding, and coagulation differ significantly between anesthetized and nonanesthetized fish. These results suggest that blood collected after MS222 anesthesia of zebrafish has altered hemostasis.

This article predicts that marine-derived bacteria should inhibit Vibrio pathogens and may be a source of unique antibiotic compounds.

This article examines the use of metal-containing polymers as a novel class of antivirals. Polymers containing platinum and to a lesser extent tin, have repeatedly demonstrated antitumor activity in vitro and in vivo against a variety of cell and tumor types. The mechanisms responsible for the antitumor activity include inducing a delay in cell proliferation and sister chromatid exchanges blocking tumor growth.

Article on evidence that mono-ADP-ribosylation of CtBP1/BARS regulates lipid storage.

Article on new markers of tumor metastasis. The authors found that expression of DP103 was significantly upregulated in the metastatic basal subtype of breast cancers in 3 independent cohorts. This elevated DP103 expression correlated with metastatic breast cancer gene signatures and was strongly associated with patient survival. This study provides the first evidence that the RNA helicase DEAD-box protein DP103 is an NF-kB target that could form part of a positive feedback loop contributing to DP103- mediated regulation of TAK1 kinase activity on the major NF-kB kinase IKK2, thus implicating DP103 in the maintenance of this oncogenic signaling arm in human cancer.

This article presents a study in which an in silico genome-scale metabolic model of steroidogenesis is used to investigate the effects of hypoxic stress on steroid hormone productions in fish. This article introduces a powerful model for pathway analysis that can lend insights on the effects of various stressor scenarios on metabolic functions.

This article posits that the frequently abrupt environmental changes accompanying much longer-term general climate change require consideration of the true nature of environmental change coupled with an expansion of focus to consider developmental phenotypic plasticity.

Article on an intimate collaboration between peroxisomes and lipid bodies.

Article examining the mechanism of Glutathione synthetase, an enzyme that belongs to the glutathione synthetase ATP-binding domain-like superfamily. A variety of structural alignment methods were applied and four highly conserved residues of human glutathione synthetase (Glu-144, Asn-146, Lys-305, and Lys-364) were identified in the binding site. The function of these was studied by experimental and computational site-directed mutagenesis.

This article assesses the relative performance of threshold selection methods in terms of resolution and reliability for disease mapping.

Article investigates the assumption that the oxygen demand remains constant throughout a bout of exercise.

Article on the function of the oxidative burst in hypersensitive disease resistance.

This article characterizes two noncatalytic chalcone isomerase (CHI)-like proteins using engineered yeast harboring all genes required for demethylxanthohumol (DMX) production.

Article discussing Tracembler, a software for in-silico chromosome walking in unassembled genomes.

This article analyzes the historical spatiotemporal behavior of the huemul (Hippocamelus bisulcus), an endangered deer endemic to Patagonia. Losing migratory traditions is a major threat, and may explain their presently prevalent skeletal diseases, reduced longevity, and lacking recolonizations for most remaining huemul subpopulations.