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Expression and Function of Transient Receptor Potential Ankyrin 1 Ion Channels in the Caudal Nucleus of the Solitary Tract (open access)

Expression and Function of Transient Receptor Potential Ankyrin 1 Ion Channels in the Caudal Nucleus of the Solitary Tract

The article describes a study that tested and confirmed the hypothesis that TRPA1 expressed in the primary sensory afferents may modulate the function of second order NTS neurons. The expression of TRPA1 was detected in presynaptic locations, but not the somata of caudal NTS neurons that did not express TRPA1 mRNA or proteins. Moreover, caudal NTS neurons did not show somatodendritic responsiveness to TRPA1 agonists, while TRPA1 immunostaining was detected only in the afferent fibers.
Date: April 26, 2019
Creator: Feng, Lin; Uteshev, Victor V. & Premkumar, Louis S.
System: The UNT Digital Library
Protein Modification by ADP-ribose via Acid-labile Linkages (open access)

Protein Modification by ADP-ribose via Acid-labile Linkages

Article describing the preparation and chemical characterization of low molecular weight conjugates that were used as models for an acetal linkage between ADP-ribose and the hydroxyl group of a protein acceptor such as serine, threonine, tyrosine, hydroxyproline, or hydroxylysine residues. The amount of modification was approximately 16 pmol of ADP-ribose per mg of total protein, and proteins modified by acid-labile linkages were detected in all subcellular fractions examined, suggesting that the scope of this modification in vivo is broad.
Date: April 7, 1995
Creator: Cervantes-Laurean, Daniel; Loflin, Paul T.; Minter, David E.; Jacobson, Elaine L. & Jacobson, Myron K.
System: The UNT Digital Library
The Multifunctional Protein Kinase C-ε in Cancer Development and Progression (open access)

The Multifunctional Protein Kinase C-ε in Cancer Development and Progression

Paper focuses on the role of protein kinase C in different processes that lead to cancer development and progression.
Date: April 10, 2014
Creator: Jain, Kirti & Basu, Alakananda
System: The UNT Digital Library
Association of Home Food Availability with Prediabetes and Diabetes among Adults in the United States (open access)

Association of Home Food Availability with Prediabetes and Diabetes among Adults in the United States

This article examined associations of home food availabilities with prediabetes and diabetes among 8929 adults (20–70 years) participating in 2007–2010 National Health and Nutrition Examination Surveys. The results show prediabetes participants had lower availability of healthy foods and higher availability of unhealthy foods, suggesting the need to improve healthy food availability at home for this population.
Date: April 25, 2020
Creator: McAtee, Jenniffer; Tao, Meng-Hua; King, Christian & Chai, Weiwen
System: The UNT Digital Library