Breast Cancer Stem-Like Cells Are Inhibited by Diosgenin, a Steroidal Saponin, by the Attenuation of the Wnt β-Catenin Signaling via the Wnt Antagonist Secreted Frizzled Related Protein-4 (open access)

Breast Cancer Stem-Like Cells Are Inhibited by Diosgenin, a Steroidal Saponin, by the Attenuation of the Wnt β-Catenin Signaling via the Wnt Antagonist Secreted Frizzled Related Protein-4

This article describes findings that demonstrate the affect of diosgenin (DG) on inhibiting the resilient breast cancer stem cells (CSCs) which could provide a benchmark for the development of DG-based therapies in breast cancer treatment.
Date: March 20, 2017
Creator: Bhuvanalakshmi, G.; Basappa; Rangappa, Kanchugarakoppal S.; Dharmarajan, Arunasalam; Sethi, Gautam; Kumar, Alan Prem et al.
System: The UNT Digital Library
Social Reward Questionaire--Adolescent Version and its association with callous-unemotional traits (open access)

Social Reward Questionaire--Adolescent Version and its association with callous-unemotional traits

This article describes a study in which the adult Social Reward Questionnaire is adapted for use with adolescents.
Date: March 20, 2017
Creator: Foulkes, Lucy; Neumann, Craig S.; Roberts, Ruth; McCrory, Eamon J. & Viding, Essi
System: The UNT Digital Library