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Pediatric Drug Research: Studies Conducted under Best Pharmaceuticals for Children Act (open access)

Pediatric Drug Research: Studies Conducted under Best Pharmaceuticals for Children Act

A letter report issued by the Government Accountability Office with an abstract that begins "About two-thirds of drugs that are prescribed for children have not been studied and labeled for pediatric use, which places children at risk of being exposed to ineffective treatment or incorrect dosing. The Best Pharmaceuticals for Children Act (BPCA), enacted in 2002, encourages the manufacturers, or sponsors, of drugs that still have marketing exclusivity--that is, are on-patent--to conduct pediatric drug studies, as requested by the Food and Drug Administration (FDA). If they do so, FDA may extend for 6 months the period during which no equivalent generic drugs can be marketed. This is referred to as pediatric exclusivity. BPCA required that GAO assess the effect of BPCA on pediatric drug studies and labeling. As discussed with the committees of jurisdiction, GAO (1) assessed the extent to which pediatric drug studies were being conducted under BPCA for on-patent drugs, including when drug sponsors declined to conduct the studies; (2) evaluated the impact of BPCA on labeling drugs for pediatric use and the process by which the labeling was changed; and (3) illustrated the range of diseases treated by the drugs studied under BPCA. GAO examined data about …
Date: March 22, 2007
Creator: United States. Government Accountability Office.
System: The UNT Digital Library
Defense Logistics: Several Factors Limited the Production and Installation of Army Truck Armor during Current Wartime Operations (open access)

Defense Logistics: Several Factors Limited the Production and Installation of Army Truck Armor during Current Wartime Operations

A letter report issued by the Government Accountability Office with an abstract that begins "In April 2005, GAO reported on factors affecting the timely production of up-armored high-mobility multi-purpose wheeled vehicles (HMMWV) and add-on armor kits for HMMWVs, as well as other items critically needed by deployed forces during Operation Iraqi Freedom. Due to high interest by Congress and the public regarding vehicle armor, GAO initiated this subsequent engagement to examine issues affecting the production and installation of armor for medium and heavy trucks. The objectives were to (1) determine the extent to which truck armor was produced and installed to meet identified requirements, (2) identify what factors affected the time to provide truck armor, and (3) identify what actions the Department of Defense (DOD) and the Army have taken to improve the timely availability of truck armor. To address these objectives, GAO collected and analyzed supply data for medium and heavy tactical trucks used by Army forces."
Date: March 22, 2006
Creator: United States. Government Accountability Office.
System: The UNT Digital Library
Social Security Reform: Greater Transparency Needed about Potential General Revenue Financing (open access)

Social Security Reform: Greater Transparency Needed about Potential General Revenue Financing

A letter report issued by the Government Accountability Office with an abstract that begins "Absent reform, Social Security's financing gap will grow until currently scheduled benefits can no longer be paid in full. Recent reform proposals often include general revenue (GR)--a major change that can have significant implications for the budget as a whole. This report addresses these issues: (1) What information is available about GR in recent proposal scorings by Social Security's Office of the Chief Actuary (OCACT)? (2) What common mechanisms, especially GR mechanisms, are used to increase program revenue? (3) What are the implications of GR for the trust fund and the federal budget? We have prepared this report under the Comptroller General's statutory authority to conduct evaluations on his own initiative as part of a continued effort to assist Congress in addressing the challenges facing Social Security."
Date: March 22, 2007
Creator: United States. Government Accountability Office.
System: The UNT Digital Library
Coast Guard Programs: Relationship between Resources Used and Results Achieved Needs to Be Clearer (open access)

Coast Guard Programs: Relationship between Resources Used and Results Achieved Needs to Be Clearer

A letter report issued by the General Accounting Office with an abstract that begins "The Coast Guard has responsibility for protecting America's ports, waterways, and waterside facilities from terrorist attacks. At the same time, the Coast Guard remains responsible for many other missions important to the nation's interests, such as conducting search and rescue and protecting important fishing grounds. GAO's past work found that despite substantial budget increases, the Coast Guard's extensive homeland security responsibilities resulted in a reduction in the levels at which the agency's ship, boat, and aircraft resources were applied to non- homeland security programs. GAO was asked to update and expand this work by analyzing: the trends in resource usage, the trends in performance results, and the implications of these trends."
Date: March 22, 2004
Creator: United States. General Accounting Office.
System: The UNT Digital Library
Combating Nuclear Smuggling: DHS Has Made Progress Deploying Radiation Detection Equipment at U.S. Ports-of-Entry, but Concerns Remain (open access)

Combating Nuclear Smuggling: DHS Has Made Progress Deploying Radiation Detection Equipment at U.S. Ports-of-Entry, but Concerns Remain

A letter report issued by the Government Accountability Office with an abstract that begins "Preventing radioactive material from being smuggled into the United States is a key national security objective. To help address this threat, in October 2002, DHS began deploying radiation detection equipment at U.S. ports-of-entry. This report reviews recent progress DHS has made (1) deploying radiation detection equipment, (2) using radiation detection equipment, (3) improving the capabilities and testing of this equipment, and (4) increasing cooperation between DHS and other federal agencies in conducting radiation detection programs."
Date: March 22, 2006
Creator: United States. Government Accountability Office.
System: The UNT Digital Library
Small and Disadvantaged Businesses: Most Agency Advocates View Their Roles Similarly (open access)

Small and Disadvantaged Businesses: Most Agency Advocates View Their Roles Similarly

A letter report issued by the General Accounting Office with an abstract that begins "The Small Business Act is one of several laws designed to enhance the participation of small and disadvantaged businesses in federal procurement--a market that reached more than $200 billion in fiscal year 2002. Section 15(k) of the act requires that all federal agencies with procurement powers establish an Office of Small and Disadvantaged Business Utilization (OSDBU) and specifies eight functions that OSDBU directors are responsible for carrying out in their roles as advocates for small businesses. GAO surveyed OSDBU directors at 24 agencies to obtain information on the extent to which the respondents (1) viewed the functions listed in section 15(k) as functions of their offices, (2) viewed other potential activities as OSDBU duties, and (3) saw potential challenges to carrying out their functions."
Date: March 22, 2004
Creator: United States. General Accounting Office.
System: The UNT Digital Library
Natural Resources: Woody Biomass Users' Experiences Offer Insights for Government Efforts Aimed at Promoting Its Use (open access)

Natural Resources: Woody Biomass Users' Experiences Offer Insights for Government Efforts Aimed at Promoting Its Use

A letter report issued by the Government Accountability Office with an abstract that begins "The federal government is placing greater emphasis on thinning vegetation on public lands to reduce the risk of wildland fire. To help defray the cost of thinning efforts, it also is seeking to stimulate a market for the resulting material, including the smaller trees, limbs, and brush--referred to as woody biomass--that traditionally have had little or no commercial value. As GAO has reported in the past, the increased use of woody biomass faces obstacles, including the high cost of harvesting and transporting it and an unpredictable supply in some locations. Nevertheless, some entities, such as schools and businesses, are utilizing the material, potentially offering insights for broadening its use. GAO agreed to (1) identify key factors facilitating the use of woody biomass among selected users, (2) identify challenges these users have faced in using woody biomass, and (3) discuss any insights that these findings may offer for promoting greater use of woody biomass. In responding to a draft of this report, the Departments of Agriculture, Energy, and the Interior all generally agreed with GAO's findings."
Date: March 22, 2006
Creator: United States. Government Accountability Office.
System: The UNT Digital Library
Operation Iraqi Freedom: DOD Should Apply Lessons Learned Concerning the Need for Security over Conventional Munitions Storage Sites to Future Operations Planning (open access)

Operation Iraqi Freedom: DOD Should Apply Lessons Learned Concerning the Need for Security over Conventional Munitions Storage Sites to Future Operations Planning

A letter report issued by the Government Accountability Office with an abstract that begins "Following the invasion of Iraq in March 2003--known as Operation Iraqi Freedom (OIF)--concerns were raised about how the Department of Defense (DOD) secured Iraqi conventional munitions storage sites during and after major combat operations. Because of the broad interest in this issue, GAO conducted this work under the Comptroller General's authority to conduct evaluations. This report examines (1) the security provided by U.S. forces over Iraqi conventional munitions storage sites and (2) DOD actions to mitigate risks associated with an adversary's conventional munitions storage sites for future operations on the basis of OIF lessons learned. To address these objectives, GAO reviewed OIF war plans, joint doctrine and policy, and intelligence reports, and interviewed senior-level DOD officials."
Date: March 22, 2007
Creator: United States. Government Accountability Office.
System: The UNT Digital Library
Money Laundering: Oversight of Suspicious Activity Reporting at Bank-Affiliated Broker-Dealers Ceased (open access)

Money Laundering: Oversight of Suspicious Activity Reporting at Bank-Affiliated Broker-Dealers Ceased

A letter report issued by the General Accounting Office with an abstract that begins "GAO reviewed the Gramm-Leach-Bliley Act (GLBA) to determine how it might affect oversight to ensure the securities industry's compliance with anti-money laundering requirements. Specifically, GAO examined (1) how federal bank regulators were overseeing suspicious activity report (SAR) compliance for broker-dealers under their jurisdiction before and after GLBA and (2) what actions the Securities and Exchange Commission (SEC) was taking to oversee SAR compliance of broker-dealers previously monitored by bank regulators. Since the passage of GLBA, the broker-dealer subsidiaries of depository institutions and their holding companies are no longer being examined to assess their compliance with SAR requirements, and although they are being examined for compliance with reporting currency transactions and other Department of the Treasury requirements. SEC has not assumed examination responsibility for broker-dealer subsidiaries because agency officials say that they lack specific authority to examine for compliance with the SAR banking rules."
Date: March 22, 2001
Creator: United States. General Accounting Office.
System: The UNT Digital Library
GHG Mitigation Potential, Costs and Benefits in Global Forests: ADynamic Partial Equilibrium Approach (open access)

GHG Mitigation Potential, Costs and Benefits in Global Forests: ADynamic Partial Equilibrium Approach

This paper reports on the global potential for carbonsequestration in forest plantations, and the reduction of carbonemissions from deforestation, in response to six carbon price scenariosfrom 2000 to 2100. These carbon price scenarios cover a range typicallyseen in global integrated assessment models. The world forest sector wasdisaggregated into tenregions, four largely temperate, developedregions: the European Union, Oceania, Russia, and the United States; andsix developing, mostly tropical, regions: Africa, Central America, China,India, Rest of Asia, and South America. Three mitigation options -- long-and short-rotation forestry, and the reduction of deforestation -- wereanalyzed using a global dynamic partial equilibrium model (GCOMAP). Keyfindings of this work are that cumulative carbon gain ranges from 50.9 to113.2 Gt C by 2100, higher carbon prices early lead to earlier carbongain and vice versa, and avoided deforestation accounts for 51 to 78percent of modeled carbon gains by 2100. The estimated present value ofcumulative welfare change in the sector ranges from a decline of $158billion to a gain of $81 billion by 2100. The decline is associated witha decrease in deforestation.
Date: March 22, 2005
Creator: Sathaye, Jayant; Makundi, Willy; Dale, Larry; Chan, Peter & Andrasko, Kenneth
System: The UNT Digital Library
FINAL ANALYTICAL RESULTS FROM THE EXAMINATION OF CORROSION ON SECTIONS OF CORROSION PROBE REMOVED FROM TANK 241-AN-107 ON 08/10/2006 (open access)

FINAL ANALYTICAL RESULTS FROM THE EXAMINATION OF CORROSION ON SECTIONS OF CORROSION PROBE REMOVED FROM TANK 241-AN-107 ON 08/10/2006

Tank Farms Operations removed an electrochemical noise probe from Tank 241-AN-107. In the field, the probe was cut into four sections, wrapped, and placed in a 55-gallon drum, This drum was delivered to the 222-S Laboratory. The 222 S Laboratory unpackaged the sections of the AN-107 electrochemical noise probe and examined the material for evidence of corrosion. Each of the four sections contained three C-ring and three bullet specimens. The specimens were examined for pitting corrosion, crevice corrosion, and stress corrosion cracking. No evidence of stress corrosion cracking was found in the stressed C-ring specimens. Minor pitting was evident on some surfaces. Crevice corrosion was the dominant type of corrosion observed.
Date: March 22, 2007
Creator: JB, DUNCAN & GA, COOKE
System: The UNT Digital Library
Proposal for Extending the UPC Memory Copy Library Functions andSupporting Extensions to GASNet, Version 2.0 (open access)

Proposal for Extending the UPC Memory Copy Library Functions andSupporting Extensions to GASNet, Version 2.0

This document outlines a proposal for extending UPC'spoint-to-point memcpy library with support for explicitly non-blockingtransfers, and non-contiguous (indexed and strided) transfers. Variousportions of this proposal could stand alone as independent extensions tothe UPC library. The designs presented here are heavily influenced byanalogous functionality which exists in other parallel communicationsystems, such as MPI, ARMCI, Titanium, and network hardware API's such asQuadrics elan, Infiniband vapi, IBM LAPI and Cray X-1. Each sectioncontains proposed extensions to the libraries in the UPC LanguageSpecification (section 7) and corresponding extensions to the GASNetcommunication system API.
Date: March 22, 2007
Creator: Bonachea, Dan
System: The UNT Digital Library
Softwood Lumber Imports from Canada: Issues and Events (open access)

Softwood Lumber Imports from Canada: Issues and Events

This report provides a concise historical account of the dispute over softwood lumber imports from Canada, summarizes the subsidy and injury evidence, and discusses current issues and events.
Date: March 22, 2006
Creator: Gorte, Ross W. & Grimmett, Jeanne J.
System: The UNT Digital Library
Article 98 Agreements and Sanctions on U.S. Foreign Aid to Latin America (open access)

Article 98 Agreements and Sanctions on U.S. Foreign Aid to Latin America

This report is on Article 98 Agreements and Sanctions on U.S. Foreign Aid to Latin America.
Date: March 22, 2007
Creator: Ribando, Clare M.
System: The UNT Digital Library
Medicaid Citizenship Documentation (open access)

Medicaid Citizenship Documentation

None
Date: March 22, 2007
Creator: unknown
System: The UNT Digital Library
Tobacco Price Support: An Overview of the Program (open access)

Tobacco Price Support: An Overview of the Program

None
Date: March 22, 2000
Creator: unknown
System: The UNT Digital Library
Qatar: Background and U.S. Relations (open access)

Qatar: Background and U.S. Relations

None
Date: March 22, 2005
Creator: unknown
System: The UNT Digital Library
Should Credit Unions Be Taxed? (open access)

Should Credit Unions Be Taxed?

None
Date: March 22, 2007
Creator: unknown
System: The UNT Digital Library
The “Farm Bill” in Brief (open access)

The “Farm Bill” in Brief

Federal farm support, food assistance, agricultural trade, marketing, and rural development policies are governed by a variety of separate laws. Many of these laws periodically have been evaluated, revised, and renewed through an omnibus, multi-year farm bill. This report discusses the "farm bill" and it's components.
Date: March 22, 2006
Creator: Becker, Geoffrey S.
System: The UNT Digital Library
Water Resources Development Act (WRDA): Army Corps of Engineers Authorization Issues in the 109th Congress (open access)

Water Resources Development Act (WRDA): Army Corps of Engineers Authorization Issues in the 109th Congress

None
Date: March 22, 2005
Creator: unknown
System: The UNT Digital Library
Safety Documentation for the M.I.C.E.2 Slot VLPC Cryocooler Cryostat (open access)

Safety Documentation for the M.I.C.E.2 Slot VLPC Cryocooler Cryostat

None
Date: March 22, 2005
Creator: Rucinski, Russell A.
System: The UNT Digital Library
Laboratory Directed Research and Development Program FY2004 (open access)

Laboratory Directed Research and Development Program FY2004

The Ernest Orlando Lawrence Berkeley National Laboratory (Berkeley Lab or LBNL) is a multi-program national research facility operated by the University of California for the Department of Energy (DOE). As an integral element of DOE's National Laboratory System, Berkeley Lab supports DOE's missions in fundamental science, energy resources, and environmental quality. Berkeley Lab programs advance four distinct goals for DOE and the nation: (1) To perform leading multidisciplinary research in the computing sciences, physical sciences, energy sciences, biosciences, and general sciences in a manner that ensures employee and public safety and protection of the environment. (2) To develop and operate unique national experimental facilities for qualified investigators. (3) To educate and train future generations of scientists and engineers to promote national science and education goals. (4) To transfer knowledge and technological innovations and to foster productive relationships among Berkeley Lab's research programs, universities, and industry in order to promote national economic competitiveness. Berkeley Lab's research and the Laboratory Directed Research and Development (LDRD) program support DOE's Strategic Goals that are codified in DOE's September 2003 Strategic Plan, with a primary focus on Advancing Scientific Understanding. For that goal, the Fiscal Year (FY) 2004 LDRD projects support every one of the …
Date: March 22, 2005
Creator: Hansen, Todd C.
System: The UNT Digital Library
Origin of The 871-keV Gamma Ray and the "Oxide" Attribute (open access)

Origin of The 871-keV Gamma Ray and the "Oxide" Attribute

This brief paper concludes our study of the origin of the 871-keV observed for many plutonium oxide samples.
Date: March 22, 2000
Creator: Peurrung, Anthony J.; Arthur, Richard J.; Geelhood, Bruce D.; Scheele, Randall D.; Elovich, Robert J. & Pratt, Sharon L.
System: The UNT Digital Library
Hoopa Valley Small Scale Hydroelectric Feasibility Project (open access)

Hoopa Valley Small Scale Hydroelectric Feasibility Project

This study considered assessing the feasibility of developing small scale hydro-electric power from seven major tributaries within the Hoopa Valley Indian Reservation of Northern California (http://www.hoopa-nsn.gov/). This study pursued the assessment of seven major tributaries of the Reservation that flow into the Trinity River. The feasibility of hydropower on the Hoopa Valley Indian Reservation has real potential for development and many alternative options for project locations, designs, operations and financing. In order to realize this opportunity further will require at least 2-3 years of intense data collection focusing on stream flow measurements at multiple locations in order to quantify real power potential. This also includes on the ground stream gradient surveys, road access planning and grid connectivity to PG&E for sale of electricity. Imperative to this effort is the need for negotiations between the Hoopa Tribal Council and PG&E to take place in order to finalize the power rate the Tribe will receive through any wholesale agreement that utilizes the alternative energy generated on the Reservation.
Date: March 22, 2009
Creator: Miller, Curtis
System: The UNT Digital Library