Phylogenetic analysis of the CDGSH iron-sulfur binding domain reveals its ancient origin (open access)

Phylogenetic analysis of the CDGSH iron-sulfur binding domain reveals its ancient origin

This article reports on the origin, evolution, and diversification of the iron-sulfur (2Fe-2S) binding motif CDGSH.
Date: November 28, 2017
Creator: Sengupta, Soham; Nechushtai, Rachel; Jennings, Patricia A.; Onuchic, José N.; Padilla, Pamela A.; Azad, Rajeev K. et al.
System: The UNT Digital Library
Testing gene-environment interactions for rare and/or common variants in sequencing association studies (open access)

Testing gene-environment interactions for rare and/or common variants in sequencing association studies

Article describes study in which novel approaches to test the effects of gene-environment (GE) interactions of rare and/or common risk, and/or protective variants in sequencing association studies were developed.
Date: March 10, 2020
Creator: Zhao, Zihan; Zhang, Jianjun; Sha, Qiuying & Hao, Han
System: The UNT Digital Library
The genome of jojoba (Simmondsia chinensis): A taxonomically isolated species that directs wax ester accumulation in its seeds (open access)

The genome of jojoba (Simmondsia chinensis): A taxonomically isolated species that directs wax ester accumulation in its seeds

Article describes the high-quality, 887-Mb genome of jojoba assembled into 26 chromosomes with 23,490 protein-coding genes.
Date: March 11, 2020
Creator: Sturtevant, Drew; Lu, Shaoping; Zhou, Zhi-Wei; Shen, Yin; Wang, Shuo; Song, Jia-Ming et al.
System: The UNT Digital Library
Gene-based association tests using GWAS summary statistics and incorporating eQTL (open access)

Gene-based association tests using GWAS summary statistics and incorporating eQTL

Article proposes a powerful and computationally efficient gene-based association test, called Overall. Using extended Simes procedure, Overall aggregates information from three types of traditional gene-based association tests and also incorporates expression quantitative trait locus (eQTL) information into a gene-based association test using GWAS summary statistics. The results show that this newly developed method can identify more significant genes than other methods.
Date: March 3, 2022
Creator: Cao, Xuwei; Wang, Xuexia; Zhang, Shuanglin & Sha, Qiuying
System: The UNT Digital Library