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Methadone-Associated Overdose Deaths: Factors Contributing to Increased Deaths and Efforts to Prevent Them (open access)

Methadone-Associated Overdose Deaths: Factors Contributing to Increased Deaths and Efforts to Prevent Them

A letter report issued by the Government Accountability Office with an abstract that begins "Prescription drug abuse is a growing public health problem. In particular, methadone-associated overdose deaths--those in which methadone may have caused or contributed to the death--have risen sharply. Before the late 1990s, methadone was used mainly to treat opioid addiction but has since been increasingly prescribed to manage pain. Taken too often, in too high a dose, or with other drugs or alcohol, methadone can cause serious side effects and death. Methadone-associated overdose deaths can occur under several different scenarios, including improper dosing levels by practitioners, misuse by patients who may combine methadone with other drugs, or abuse--using the drug for nontherapeutic purposes. This report examines the regulation of methadone, factors that have contributed to the increase in methadone-associated overdose deaths, and steps taken to prevent methadone-associated overdose deaths. GAO reviewed documents, laws and regulations, data, and research from relevant state and federal agencies, including the Drug Enforcement Administration (DEA) and the Substance Abuse and Mental Health Services Administration (SAMHSA). GAO also interviewed federal officials, officials in five selected states, officials from professional associations and advocacy groups, and experts in pain management, addiction treatment, and forensic sciences."
Date: March 26, 2009
Creator: United States. Government Accountability Office.
Object Type: Report
System: The UNT Digital Library
Defense Management: Key Challenges Should be Addressed When Considering Changes to Missile Defense Agency's Roles and Missions (open access)

Defense Management: Key Challenges Should be Addressed When Considering Changes to Missile Defense Agency's Roles and Missions

Testimony issued by the Government Accountability Office with an abstract that begins "To more quickly field ballistic missile defenses, the Missile Defense Agency (MDA) has been exempted from traditional Department of Defense (DOD) requirements development, acquisition, and oversight processes since its creation in 2002. Instead, MDA has unique roles and missions to develop and field weapon systems that address a variety of ballistic missile threats. To date, MDA has spent about $56 billion and plans to spend about $50 billion more through 2013 to develop an integrated Ballistic Missile Defense System. The system consists of a layered network of capabilities that includes defensive components such as sensors, radars, interceptors, and command and control. In reviews of DOD's approach to acquire, operate, and maintain ballistic missile defense systems, GAO has previously reported on several challenges that have stemmed from the broad flexibilities provided to MDA. This testimony summarizes the challenges facing DOD in acquiring and operating its ballistic missile defense systems and describes DOD's efforts to improve transparency and accountability. This statement is based primarily on previously issued GAO reports and testimonies. GAO also reviewed documents and interviewed key officials to update past work and identify DOD and MDA efforts to …
Date: March 26, 2009
Creator: United States. Government Accountability Office.
Object Type: Text
System: The UNT Digital Library
Human Subjects Research: Undercover Tests Show the Institutional Review Board System Is Vulnerable to Unethical Manipulation (open access)

Human Subjects Research: Undercover Tests Show the Institutional Review Board System Is Vulnerable to Unethical Manipulation

Testimony issued by the Government Accountability Office with an abstract that begins "Millions of Americans enroll in clinical studies of experimental drugs and medical devices each year. Many of these studies are meant to demonstrate that products are safe and effective. The Department of Health and Human Services' (HHS) Office for Human Research Protections (OHRP) and the Food and Drug Administration (FDA) are responsible for overseeing aspects of a system of independent institutional review boards (IRB). IRBs review and monitor human subjects research, with the intended purpose of protecting the rights and welfare of the research subjects. GAO investigated three key aspects of the IRB system: (1) the process for establishing an IRB, (2) the process through which researchers wishing to apply for federal funding assure HHS their human subjects research activities follow ethical principles and federal regulations, and (3) the process that medical research companies follow to get approval for conducting research on human subjects. GAO investigated these three aspects of the IRB system by creating two fictitious companies (one IRB and one medical device company), phony company officials, counterfeit documents, and a fictitious medical device."
Date: March 26, 2009
Creator: United States. Government Accountability Office.
Object Type: Text
System: The UNT Digital Library
Port Aransas South Jetty (Port Aransas, Tex.), Vol. 39, No. 13, Ed. 1 Thursday, March 26, 2009 (open access)

Port Aransas South Jetty (Port Aransas, Tex.), Vol. 39, No. 13, Ed. 1 Thursday, March 26, 2009

Weekly newspaper from Port Aransas, Texas on Mustang Island that includes local, state and national news along with extensive advertising.
Date: March 26, 2009
Creator: Judson, Mary Henkel
Object Type: Newspaper
System: The Portal to Texas History
Greensheet (Houston, Tex.), Vol. 40, No. 93, Ed. 1 Thursday, March 26, 2009 (open access)

Greensheet (Houston, Tex.), Vol. 40, No. 93, Ed. 1 Thursday, March 26, 2009

Free weekly newspaper that includes business and classified advertising.
Date: March 26, 2009
Creator: unknown
Object Type: Newspaper
System: The Portal to Texas History
Greensheet (Houston, Tex.), Vol. 40, No. 92, Ed. 1 Thursday, March 26, 2009 (open access)

Greensheet (Houston, Tex.), Vol. 40, No. 92, Ed. 1 Thursday, March 26, 2009

Free weekly newspaper that includes business and classified advertising.
Date: March 26, 2009
Creator: unknown
Object Type: Newspaper
System: The Portal to Texas History
[Clipping: Female pilot supports Stewart's mission] (open access)

[Clipping: Female pilot supports Stewart's mission]

Newspaper clipping of an article about former WASP member Helen Wyatt Snapp's experiences serving as a pilot in WWII. The clipping includes other articles about local and world news, as well as advertisements.
Date: March 26, 2009
Creator: Van Pool, J. Elise
Object Type: Clipping
System: The Portal to Texas History
North Texas Daily (Denton, Tex.), Vol. 93, No. 34, Ed. 1 Thursday, March 26, 2009 (open access)

North Texas Daily (Denton, Tex.), Vol. 93, No. 34, Ed. 1 Thursday, March 26, 2009

Daily student newspaper from the University of North Texas in Denton, Texas that includes local, state and campus news along with advertising.
Date: March 26, 2009
Creator: unknown
Object Type: Newspaper
System: The Portal to Texas History
Texas Jewish Post (Fort Worth, Tex.), Vol. 63, No. 13, Ed. 1 Thursday, March 26, 2009 (open access)

Texas Jewish Post (Fort Worth, Tex.), Vol. 63, No. 13, Ed. 1 Thursday, March 26, 2009

Weekly Jewish newspaper from Fort Worth, Texas that includes local, state and national news along with extensive advertising.
Date: March 26, 2009
Creator: Wisch, Rene
Object Type: Newspaper
System: The Portal to Texas History
The Canadian Record (Canadian, Tex.), Vol. 119, No. 13, Ed. 1 Thursday, March 26, 2009 (open access)

The Canadian Record (Canadian, Tex.), Vol. 119, No. 13, Ed. 1 Thursday, March 26, 2009

Weekly newspaper from Canadian, Texas that includes local, state and national news along with some advertising.
Date: March 26, 2009
Creator: Brown, Laurie Ezzell
Object Type: Newspaper
System: The Portal to Texas History
The Bastrop Advertiser (Bastrop, Tex.), Vol. 156, No. 7, Ed. 1 Thursday, March 26, 2009 (open access)

The Bastrop Advertiser (Bastrop, Tex.), Vol. 156, No. 7, Ed. 1 Thursday, March 26, 2009

Semi-weekly newspaper from Bastrop, Texas that includes local, state and national news along with advertising.
Date: March 26, 2009
Creator: Wright, Cyndi
Object Type: Newspaper
System: The Portal to Texas History
[ActBlue Texas Stonewall Democratic Caucus reporting center] (open access)

[ActBlue Texas Stonewall Democratic Caucus reporting center]

A report for the Texas Stonewall Democratic Caucus from their account with ActBlue. The report lists contribution summary of committee's contributions and fundraisers.
Date: March 26, 2009
Creator: unknown
Object Type: Report
System: The UNT Digital Library
Greensheet (Fort Worth, Tex.), Vol. 32, No. 355, Ed. 1 Thursday, March 26, 2009 (open access)

Greensheet (Fort Worth, Tex.), Vol. 32, No. 355, Ed. 1 Thursday, March 26, 2009

Free weekly newspaper that includes business and classified advertising.
Date: March 26, 2009
Creator: unknown
Object Type: Newspaper
System: The Portal to Texas History
Today Newspapers (Duncanville, Tex.), Vol. 1, No. 2, Ed. 1 Thursday, March 26, 2009 (open access)

Today Newspapers (Duncanville, Tex.), Vol. 1, No. 2, Ed. 1 Thursday, March 26, 2009

Weekly newspaper from Duncanville, Texas that includes local, state, and national news along with advertising.
Date: March 26, 2009
Creator: unknown
Object Type: Newspaper
System: The Portal to Texas History
The Greensheet (Arlington-Grand Prairie, Tex.), Vol. 32, No. 353, Ed. 1 Thursday, March 26, 2009 (open access)

The Greensheet (Arlington-Grand Prairie, Tex.), Vol. 32, No. 353, Ed. 1 Thursday, March 26, 2009

Free weekly newspaper that includes business and classified advertising.
Date: March 26, 2009
Creator: unknown
Object Type: Newspaper
System: The Portal to Texas History
Greensheet (Fort Worth, Tex.), Vol. 32, No. 354, Ed. 1 Thursday, March 26, 2009 (open access)

Greensheet (Fort Worth, Tex.), Vol. 32, No. 354, Ed. 1 Thursday, March 26, 2009

Free weekly newspaper that includes business and classified advertising.
Date: March 26, 2009
Creator: unknown
Object Type: Newspaper
System: The Portal to Texas History
Timpson & Tenaha News (Timpson, Tex.), Vol. 27, No. 12, Ed. 1 Thursday, March 26, 2009 (open access)

Timpson & Tenaha News (Timpson, Tex.), Vol. 27, No. 12, Ed. 1 Thursday, March 26, 2009

Weekly newspaper from Timpson, Texas that includes local, state, and national news along with advertising.
Date: March 26, 2009
Creator: Alexander, Nancy
Object Type: Newspaper
System: The Portal to Texas History
Cooper Review (Cooper, Tex.), Vol. 129, No. 13, Ed. 1 Thursday, March 26, 2009 (open access)

Cooper Review (Cooper, Tex.), Vol. 129, No. 13, Ed. 1 Thursday, March 26, 2009

Weekly newspaper from Cooper, Texas that includes local, state, and national news along with advertising.
Date: March 26, 2009
Creator: Palmer, Roger
Object Type: Newspaper
System: The Portal to Texas History
Archer County News (Archer City, Tex.), No. 13, Ed. 1 Thursday, March 26, 2009 (open access)

Archer County News (Archer City, Tex.), No. 13, Ed. 1 Thursday, March 26, 2009

Weekly newspaper from Archer City, Texas that includes local, state, and national news along with advertising.
Date: March 26, 2009
Creator: Lewis, Shelley
Object Type: Newspaper
System: The Portal to Texas History
Polk County Enterprise (Livingston, Tex.), Vol. 127, No. 26, Ed. 1 Thursday, March 26, 2009 (open access)

Polk County Enterprise (Livingston, Tex.), Vol. 127, No. 26, Ed. 1 Thursday, March 26, 2009

Semi-weekly newspaper from Livingston, Texas that includes local, state and national news along with advertising.
Date: March 26, 2009
Creator: Reddell, Valerie
Object Type: Newspaper
System: The Portal to Texas History
Defense Acquisitions: Key Considerations for Planning Future Army Combat Systems (open access)

Defense Acquisitions: Key Considerations for Planning Future Army Combat Systems

Testimony issued by the Government Accountability Office with an abstract that begins "The Future Combat System (FCS) program--which comprises 14 integrated weapon systems and an advanced information network--is the centerpiece of the Army's effort to transition to a lighter, more agile, and more capable combat force. The substantial technical challenges, the cost of the program, and the Army's acquisition strategy are among the reasons why the program is recognized as needing special oversight and review. This testimony is based on GAO's March 12, 2009 report and addresses knowledge gaps that will persist in the FCS program as Congress is asked to make significant funding commitments for development and production over the next several years."
Date: March 26, 2009
Creator: United States. Government Accountability Office.
Object Type: Text
System: The UNT Digital Library
The Sachse News (Sachse, Tex.), Vol. 5, No. 9, Ed. 1 Thursday, March 26, 2009 (open access)

The Sachse News (Sachse, Tex.), Vol. 5, No. 9, Ed. 1 Thursday, March 26, 2009

Weekly newspaper from Sachse, Texas that includes local, state and national news along with advertising.
Date: March 26, 2009
Creator: Fisher, Donnita Nesbit
Object Type: Newspaper
System: The Portal to Texas History
[Letter From David P. Marion to Catherine Parker, March 26, 2009] (open access)

[Letter From David P. Marion to Catherine Parker, March 26, 2009]

Letter from David P. Marion to Catherine Parker Chatham praising her and the Women Airforce Service Pilots for their great service during World War II.
Date: March 26, 2009
Creator: Marion, David P.
Object Type: Letter
System: The Portal to Texas History
Rio Grande Herald (Rio Grande City, Tex.), Vol. 96, No. 12, Ed. 1 Thursday, March 26, 2009 (open access)

Rio Grande Herald (Rio Grande City, Tex.), Vol. 96, No. 12, Ed. 1 Thursday, March 26, 2009

Weekly newspaper from Rio Grande City, Texas that includes local, state and national news along with extensive advertising.
Date: March 26, 2009
Creator: Roberts, Kenneth
Object Type: Newspaper
System: The Portal to Texas History