It is shown that rifampicin, and especially its relative dimethyl-N-benzyl-N-desmethyl rifampicin, can inhibit focus formation by Moloney sarcoma virus on BALB/3T3 tissue cultures. At a dose level of 10 {micro}g/ml DMB appears to totally inhibit focus formation while reducing virus replication by at least a factor of fifty and cell proliferation by only a factor of three. These observations, taken together with those of others, suggest a role for the hybrid RNA-DNA dependent DNA polymerase and the gene for its synthesis both in normal cell processes and in the transformation process.

On December 18, 1970, at 7:30 a.m., PST, a venting occurred at the Nevada Test Site in conjunction with the Baneberry test. The Lawrence Radiation Laboratory (LRL) Bio-Medical Research Division and the University of Utah responded to this event by activating their jointly operated air-sampling network and by gathering forage, milk, and animal samples. These data are used to calculate the dose to humans from inhalation, submersion, and food-chain contamination; food-chain contamination calculations are limited to the cow-milk pathway, but included bovine inhalation. The question of food-chain contamination is explored under both the actual situation that dairy cows were fed stored feed and under the hypothetical situation that dairy cows were fed fresh feed. Our results show that {sup 131}I was the significant radionuclide emitted by the event and that the strongest dose was received by the thyroid glands of both foraging animals and humans. The integrated concentrations of {sup 131}I were higher in the northern part of Utah; the maximum value of 1100 pCi h m{sup {minus}3} was recorded at Draper (near Salt Lake City). For conservative results, we calculated the dose to a child rather than an adult. For the actual conditions following the venting, we estimate on …

This document is intended to serve both as an historical record and final status report concerning the K Reactor hydriding problem which has been under study since its discovery in 1965. If neither of the K reactors are restarted, this will serve as an historical record which might be of some use to those using Zircaloy components in either the power reactor or chemical industries. (Its classification would limit such use.) If either of the K`s are reactivated, hydriding will again become an active subject since its deleterious effects on the tubes will have a significant bearing on future reactor operations. No attempt will be made to review or report on all work done on this problem but a complete list of references is appended. It is assumed that copies, or microfilms, of these references will be available for some time to come.

This document summarizes by stack number the amount of radioactivity discharged from the facilities of Chemical Processing Division, Atlantic Richfield Hanford Company. Emission data for 231-Z Building and 2724-W, Laundry Building, which are operated by other AEC Contractors are not available for this report. Total beta, alpha and I{sup l3l} radioactive emissions from the stacks for 1970 were as follows: alpha (Pu, assumed) 1.59 {times} 10{sup {minus}1} C, alpha (U, assumed) 1.44 {times} 10{sup {minus}3} C, beta 1.93C, and I{sup 131} 4.92 {times} 10{sup {minus}1} C. Air samples taken continuously from gaseous release facilities were analyzed for total beta and alpha activity (and iodine activity, where applicable). Where sample data were not available, the total radioactive emission was adjusted by using the average emission rate prior to the subject period; or where activity was near constant, by using the daily average as a base. A gamma scan of the 291-S stack is included in the report.

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Declassifted 31 Aug 1973. Information on the SNAP research and development programs is presented concerning S8DR core examination, ZrH reactor engineering and design, reactor thermoelectric system engineering, thermoelectric converter development, component development, and fuel development. (DCC)

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Biweekly, comprehensive compilation of decisions, reports, public notices, and other documents of the U.S. Federal Communications Commission.

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This report is a selected bibliography that outlines major national labor disputes from the years 1950 through 1970.

This report collects major proposals for health insurance as a response to an increased public interest.

This report outlines six pieces of legislation that relates to the power of the President to commit American resources and troops in Southeast Asia were enacted by the 91st Congress.

This bibliography provides resources for examples of youth culture and campus protests through the years 1969 through 1971.

This report is regarding the Drug Abuse and how is acceptable in society.

This report associates receipts and expenditures of the United States budget as spent by each President.

This report discusses statutes that authorizes federal assistance for federal delinquency programs, along with drug use education.

This report is intended to present some statistics and commentary which give dimension and perspective to the problems of visitor pressures on the National Park system.

This report addresses Violence as a Political Technique Selected References from 1968 through 1971.