Report issued by the Brookhaven National Laboratory discussing the work conducted by the lab during the fiscal year of 1954. As stated in the introduction, "the progress and trends of the research program are presented along with a description of the operational, service, and administrative activities of the Laboratory" (p. v).

Report issued by the Brookhaven National Laboratory discussing the formats and procedures used at the ENDF Neutron Cross Section Library. As stated in the introduction, "this report describes the philosophy, data formats, and procedures that have been developed for the Evaluated Nuclear Data File (ENDF)" (p. 1-1). This report includes tables, and illustrations.

Report describes a few experiments designed to test the analysis of some systems where chemical energy can be converted to electric energy. From Abstract: "If a chemocouple is defined as an isothermal closed circuit, composed of two or more homogeneous ionic aqueous phases separated by two or more barriers of different sets of ionic transport numbers, we find that a spontaneous electric current flows in the closed circuit."

The report objective is to establish the amino acid composition of sperm whale myoglobin. From Summary: "The homoprotein that comprises 96% by weight of the protein present in crystalline sperm whale myoglobin may be received into at least five components by chromatography on the carboxylic resin IRC-50."

Technical report describing how to estimate the energy deposition efficiency of the kinetic energy of recoiling fragments from nuclear fission in a chemically reacting system. Since it is not always possible to directly measure the deposition the report describes how to estimate through the aid of fission fragment range data.

Technical report describing "A means for automatically determining the coordinates of a point at the center of a bubble chamber track." from the abstract.

Technical report describing a bubble chamber film track measuring stage designed for maximum versatility that was build at Brookhaven National Laboratory. The report includes photographs and diagrams of the device.

Technical report presenting preliminary results obtained in the static corrosion test program to screen promising construction materials for a proposed liquid fuel power breeder reactor.

Technical report describing the downtime of the Brookhaven National Laboratory nuclear reactor and changes made to the reactor facility in March 1952.

This report discusses the alternating gradient synchrotron at Brookhaven National Laboratory and provides a preliminary discussion on experiences to date and experiments in progress.

Technical report outlining the nature and effects of energy loss and radiation in biological materials during radiobiological processes.

Technical report outlining the effects of chromosomal abnormalities in tetraploid Argentine flint maize pollination, and subsequent generations.

The method of collection and the subsequent analysis of the hematological data accumulated by the Joint Commission of the Investigation of the Early Effects of the Atomic Bomb in Japan, have been described. In the present investigations, an additional analysis of the hematological data was made to investigate a possible relationship between leukopenia and the mortality rate within the first nine weeks following the bombings. It has been frequently observed in laboratory animals exposed to ionizing radiation that the extent of the fall in the white blood count reflects the dose of radiation received. Smith et al have demonstrated that in mice survival can be related to the depression of the granulocyte count at various times following radiation. Cronkite and Brecher and Cronkite, Bond and Dunham inferred that the hematological response could be used as a biologic dosimeter for exposed human beings. This report is concerned with the study of the response of the white blood cells to ionizing radiation resulting from the atomic bomb detonation in Japan.

In discussing this subject, data on radiation induced mammary gland neoplasia in the rat indicating that direct interaction between the radiation and target tissue is necessary for maximum neoplasia induction will be presented mainly. Other types of radiation induced neoplasia, in which little or no information on the mechanisms involved is available, will be discussed briefly. In particular, investigations on radiation induced mouse lymphoma will be reviewed, in which neoplasia appears to be an abscopal effect. Implications of these data will be discussed, particularly with regard to possible mechanisms involved, and extrapolation to man.

The generic term "chemonuclear" has been assigned to any chemical process system using nuclear energy as the prime energy source. The type of effect which induces the chemical change, or produces the chemical is of importance in classifying the type of chemonuclear process, or reactor involved. Four types of effects are identified for this classification. These are radiation, thermal, electrical, and photolytic effects. The radiation effects include the interaction with matter of high energy particles, or photons carrying energy in the range of a million electron volts (MEV) or higher, and causing primarily ionization effects. Thermal effects include transfer of thermal energy to matter and usually is directed towards producing a thermodynamic equilibrium in the system. Electrical effects are concerned with interaction with matter of particles carrying energy in the range of electron volts up to thousands of electron volts (EV to KEV). The photolytic effects utilize photon energy in the range of infrared through the visible to the ultraviolet radiation (IR, Visible, and UV). As is evident, this classification is somewhat arbitrary since it is primarily based on a division of the energy spectrum which is in reality continuous. It does, however, separate the more conventional methods of inducing …

The pioneer study by Benjamin and Sluka in 1908 on inhibition of antibody formation by X-rays revealed the importance of the temporal relationship between exposure to radiation and injection of antigen. X-radiation delivered three days before injection of beef serum inhibited precipitin formation in rabbits. A similar exposure to X-rays delivered three days after injection of the antigen failed to repress production of specific antibody. These observations were partially confirmed in 1915 when Hektoen reported inhibition of hemolysin production in the rat when X-radiation was delivered either before or after injection of sheep red cells. Although an absolute difference in radiosensitivity was not evident, the depressant effect of radiation on antibody production appeared to be less effective when radiation was given after injection of the antigen.

The spectra of KHF2, KH2F3, NaH2F3, liquid and solid HF were measured between 1200 and 30 cm-1 by the inelastic scattering of "cold neutrons" (0.005e.v.). The spectrum of KHF2 is in agreement with previous infrared measurements and shows a peak at 147 mV corresponding to a deformation frequency v2 of the F-H-F group and a broad peak at 13 mV due to a libration of this group. The observed spectra for KH2F3, NaH2F3 solid and liquid HF were compared with that for KHF2 considering the known results that the F-F distance increases, the position of the H atom between the two fluorines becomes more asymmetrical, and the strength of the hydrogen bond decreases in going from the HF2- ion to H2F3- ion to HF. In this comparison the known structure of the H2F3- ion is considered as being intermediate between that of HF2- and the zig-zag hydrogen bonded chains in solid HF. As a result, the lines observed at 112 mV and 67 mV in the H2F3- spectra and in HF respectively are associated with the deformation frequency v2 of the H-F-H group in these compounds. In addition the spectra of H2F3- ions show a peak at a 15 mV …

The rapid advances in many technologically important areas have not only served to accentuate the increased demands for high temperature metals and ceramics but have necessitated a more through knowledge of their physical properties when exposed to high temperature service. Toward this latter end, the use of X-ray diffraction has proved an invaluable tool in providing data of regions of thermal stability, expansion coefficients, solid solubility limits, and phase transformations by direct examination at temperature. Since this Laboratory has for some time now been engaged in the study of refractory nuclear materials, it was thought desirable to employ and possibly extend this technique to temperatures ranging up to 3000°C. This communication will describe the equipment developed for this purpose, with experimental results to be described in subsequent publications.

Initiation of reactions by intermittent irradiation is frequently encountered in physical, chemical, and biological systems. Mathematical expressions for transient and steady state concentrations of reactive species in these systems are useful for predicting performance and for research purposes. A general method of formulation of the intermittent irradiation problem is presented herein, and illustrative solutions are obtained for radioactive decay chains and for the rotating sector method.

The desired neutron spectrum for the High Flux Beam Reactor under construction at BNL requires use of U-Al fuel elements with more then 30 wt% U235 in the meat. The operating cycle of this reactor requires a minimum burn-up of 20%, and preferably 40% of the uranium in the element.

Cell proliferation on the actively growing periosteal surface of the femur of rabbits aged two weeks, has been investigated using autoradiographic techniques. Injections of tritiated glycine and tritiated thymidine were given simultaneously and the animals sacrificed at intervals from one hour to 5 days after injection. The glycine labelled the position of the bone surface at the time of injection and the thymidine labelled the cells which were synthesizing DNA . The rate of increase in the cell population was determined by counting the number of cells beyond the glycine label at different times after injection. The cell kinetics of the fibroblast--pre-osteoblast--osteoblast--osteocyte system has been studied. The fibroblasts are relatively unimportant from the point of view of increase in the cell population. The main site of cell proliferation is the layer of preosteoblasts on the periosteal surface. The rate of movement of cells from the pre-osteoblast to the osteoblast and osteocyte compartments has been measured. The incorporation of osteoblasts into the bone is not a random process, but it appears that the osteoblast must spend a certain time on the periosteal surface before becoming either an osteocyte or a relatively inactive osteoblast lining a haversian canal. During its most active …

A study of the cell kinetics on the actively growing periosteal surface of the femur of rabbits ages two weeks has been continues. A single injection of tritiated thymidine was given and the rabbits killed from one hour to four days after injection. The grain count spectra of the different cell types, pre-osteoblast, osteoblast and osteocyte, have been compared at different times after injection. The results showed evidence for the uptake of thymidine in nuclei which is not associated with cell division. A small percentage of osteoblasts was initially labelled at one hour and there was evidence that the majority of these had not divided by 3 or 4 days after injection. Some thymidine labelled cells had also become osteocytes without division. Furthermore, it appeared that a considerable fraction of the initially labelled pre-osteoblasts did not divide. The S-period for the pre-osteoblasts and osteoblasts was measured using a double-labelled thymidine technique.

Studies carried on since 1956 indicate that the prosaic breeding procedure of sibbing among the most perennial segregates in the hybrid of 4n maize x 4n perennial teosinte quickly restores perennialism to 50% maize tetraploids through increasing the expression of the rhizomatous habit under selection pressure. Similarly, only two generations of selection at the 75% maize level have resulted in a progressive recovery of the perennial expressive. A high degree of maize-likeness therefore appears to be compatible with the perennial expression at the 4n level.

Studies of linkage in polyploids have been exceedingly rare. Only three previous studies of linkage in autotetraploid maize have been reported. Murray (1944), in a limited analysis of crossing over among 4 linked markers in chromosome 2, found varying degree of difference in linkage values between 2n and 4n maize in the three interposed segments. Dempsey (1956) found linkage values wx - c region of chromosome 9 to correspond closely between autotetraploid and diploid maize. More recently Welch (1962), in a more extensive analysis of linkage among the same group of chromosome 2 markers studied earlier by Murray, concluded that although individual progenies varied, linkage values in diploid and tetraploid maize, with some exceptions, are similar. Limited data from one segment of the allotetraploid of perennial teosinte x maize (Emerson and Beadle 1932) probably represent the only reported linkage tabulation in this type of polyploid. A further study of linkage of Zea polyploids seemed worthwhile because of the increasing practical importance of polyploids, of the possibility of adding to fundamental knowledge of tetraploid cytology and genetics, and of the bearing such work may have upon the question of the taxonomic affinities of maize.